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The map label for this gene is yhcZ [H]

Identifier: 52784773

GI number: 52784773

Start: 1004689

End: 1005342

Strand: Direct

Name: yhcZ [H]

Synonym: BLi01001

Alternate gene names: 52784773

Gene position: 1004689-1005342 (Clockwise)

Preceding gene: 52784772

Following gene: 52784774

Centisome position: 23.79

GC content: 43.88

Gene sequence:

>654_bases
ATGGAGAAGGTGAAAATCATCATTGCCGATGATCATCATATTGTCAGAAAAGGGCTCTTGTTTTTCTTCAAAACAAAAAG
CGATTTTGATGTTATCGGAGAGGCTTCGACAGGTATCGAGGCGCTCGATGTCTTGCGAAAACGTGAGGCAGACATCGTAT
TAATGGATTTATCAATGCCTGATATGGACGGCATTGAGGCGACAAAGCGAATAAAAAAGGAATATCCGTCTGTCAAAGTC
ATAGCGCTGACAAGCTATGCGGACGAGAGCTATGTGATTCCCGCCATCCAGGCGGGAGCCTGTGCCTATCAGCTGAAAGA
CGCCGAGCCTGATGAACTTGTCGAGACGATCCGCGCAGTTTATGGCGGGAGATACTCATTGGATCCGAACATCATGTCCC
ACGTCTTTCACCATGTGTCACAGGCGGATGAGAAAGAAAAAATACATCAATTGACAAATAGAGAAAAAGATGTTTTATTG
GAAATTACGAAAGGGAAAAGCAATAAAGAAATTGCAGCATCTTTATTTATCAGCGAAAAAACGGTAAAAACCCATGTATC
CAATCTGCTTTCAAAGCTTGGCTTATCCGATCGCACGCAAGCCGCGCTTTTTGCAGTAAAACACGGACTACAACAAAATG
ACGGGAGAGGATGA

Upstream 100 bases:

>100_bases
GGACGGAAAAAGCGGGCGGCACGCTTTTGATCACCTCCGCAATCGGTAAGGGGACAAAAATCCGGGCGGTTTTGCCTATG
AAGGAGAAGGGGGAGGCAGG

Downstream 100 bases:

>100_bases
CCAAATGAAAATAACCGTAATTAGCGGAACTGCGAGAAAACAGGGCAGAACGCGGATCGCCGCTTCCTATATCGCCCGCG
CTTATCAGGCTGAGCTTATC

Product: YhcZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MEKVKIIIADDHHIVRKGLLFFFKTKSDFDVIGEASTGIEALDVLRKREADIVLMDLSMPDMDGIEATKRIKKEYPSVKV
IALTSYADESYVIPAIQAGACAYQLKDAEPDELVETIRAVYGGRYSLDPNIMSHVFHHVSQADEKEKIHQLTNREKDVLL
EITKGKSNKEIAASLFISEKTVKTHVSNLLSKLGLSDRTQAALFAVKHGLQQNDGRG

Sequences:

>Translated_217_residues
MEKVKIIIADDHHIVRKGLLFFFKTKSDFDVIGEASTGIEALDVLRKREADIVLMDLSMPDMDGIEATKRIKKEYPSVKV
IALTSYADESYVIPAIQAGACAYQLKDAEPDELVETIRAVYGGRYSLDPNIMSHVFHHVSQADEKEKIHQLTNREKDVLL
EITKGKSNKEIAASLFISEKTVKTHVSNLLSKLGLSDRTQAALFAVKHGLQQNDGRG
>Mature_217_residues
MEKVKIIIADDHHIVRKGLLFFFKTKSDFDVIGEASTGIEALDVLRKREADIVLMDLSMPDMDGIEATKRIKKEYPSVKV
IALTSYADESYVIPAIQAGACAYQLKDAEPDELVETIRAVYGGRYSLDPNIMSHVFHHVSQADEKEKIHQLTNREKDVLL
EITKGKSNKEIAASLFISEKTVKTHVSNLLSKLGLSDRTQAALFAVKHGLQQNDGRG

Specific function: Member of the two-component regulatory system yhcY/yhcZ [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=33.6538461538462, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788521, Length=208, Percent_Identity=35.0961538461538, Blast_Score=126, Evalue=9e-31,
Organism=Escherichia coli, GI1786747, Length=195, Percent_Identity=31.7948717948718, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=33.1658291457286, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787473, Length=207, Percent_Identity=32.3671497584541, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788712, Length=187, Percent_Identity=27.807486631016, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788546, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787277, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082052, Length=114, Percent_Identity=28.0701754385965, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=35.7798165137615, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=147, Percent_Identity=27.2108843537415, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24195; Mature: 24195

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVKIIIADDHHIVRKGLLFFFKTKSDFDVIGEASTGIEALDVLRKREADIVLMDLSMP
CCEEEEEEECCHHHHHHHHEEEEECCCCCCEECCCCCCHHHHHHHHHCCCCEEEEECCCC
DMDGIEATKRIKKEYPSVKVIALTSYADESYVIPAIQAGACAYQLKDAEPDELVETIRAV
CCCCHHHHHHHHHHCCCEEEEEEEEECCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHH
YGGRYSLDPNIMSHVFHHVSQADEKEKIHQLTNREKDVLLEITKGKSNKEIAASLFISEK
HCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHH
TVKTHVSNLLSKLGLSDRTQAALFAVKHGLQQNDGRG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEKVKIIIADDHHIVRKGLLFFFKTKSDFDVIGEASTGIEALDVLRKREADIVLMDLSMP
CCEEEEEEECCHHHHHHHHEEEEECCCCCCEECCCCCCHHHHHHHHHCCCCEEEEECCCC
DMDGIEATKRIKKEYPSVKVIALTSYADESYVIPAIQAGACAYQLKDAEPDELVETIRAV
CCCCHHHHHHHHHHCCCEEEEEEEEECCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHH
YGGRYSLDPNIMSHVFHHVSQADEKEKIHQLTNREKDVLLEITKGKSNKEIAASLFISEK
HCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHH
TVKTHVSNLLSKLGLSDRTQAALFAVKHGLQQNDGRG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]