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The map label for this gene is thrS [H]

Identifier: 52784711

GI number: 52784711

Start: 938943

End: 940268

Strand: Direct

Name: thrS [H]

Synonym: BLi00937

Alternate gene names: 52784711

Gene position: 938943-940268 (Clockwise)

Preceding gene: 52784710

Following gene: 52784712

Centisome position: 22.24

GC content: 55.05

Gene sequence:

>1326_bases
TTGTCAATTCGCATTAAACTGCCTGACGGGTCCGTCAGAGAATTTGAGGAGGAAGCAAGTATTGAAGATGTTGCTGCTTC
CATTAGCTGCGGTCTGGAACATGCGGTTGCAGGTAAATTAAACGGAAAGCTTGTAGATTTATCAACTCCGCTTCAGGACG
GTGCACTCGTTGAAATTGTCACCCGGGACTCAGCAGAAGGACAGAAGATCGTGCGTGAAAAATCGCGGGGGAAAGGGCGT
ATTGTGGCACTTGACGCAGCACGGGGACTGGCGGTCATCGGGATGTATTTGCAGCACTTCGCCTTGAACGAAACGAACGG
TTCGATCGTTTCCGGGAATACGACGCTTCTATTTGTGCTTTGCGGCGGAATCTCCTATTCGATCATGGCCGGGCGCATGA
TGGACAGAGGAATGGAGCCGGCCGCATTTCGGACGCGGATGCTTGCCCGCGCGGTATTTATCGATATGATAGGATATCTG
CTCATCATGCTGAATACTCCGTTCGGGGTGATTTTGCCGGCTTATGCTGCACTTTTTGTGCTGGCATTGGTGCTGATTCG
CCGTTCGACGCGTGTGCTCGTTACAACAGCAGCTGTTTTGCTTGCGGTGAGCCCGCCGCTGATGATTCTCGGAGGGAGCG
TCCTGTCGGGAGCAAACTTGCTTGGCGATATTGCAGGCGGCCCGATGTCGGCGCTCGCACTTGCACCCGCTTTCGTCGCC
GGTATGGCAATCGGGCGCTTTGATCTGACCAGGATGCGTACGGCACTTTCGCTAGTAAGCAGCGGCGCAGTCATGCTTAT
CGTCTCTAAGTTATTGGGCGTTTTCGTTCTTCCTTGGCTGAGCCGTTCCTTCGAAGAATGGCTCGTAAGTGTTCAAGGCA
CCGCCGGCGCCGAGCCGGATCAGTATGCAATCTGGCCGCACAACGTGGCACCGCCGCTTTGGCACAATCTTCTTTCGATA
GCTCCGCACAGTGCGTCAACTTTCCAGACGATGCTGGGGCTTGGGGCTGCCTTTCTGGTTCTAGGAATGGTATGTCTCGT
GCCGCAGAAGATTTCTGCAGTGCTAAAGCCGTTCGCGGGAGTCGGACGTGTAGCGTTGACGATGTATGCAGCTCAGTTTG
TTGTCATATGGGCTCTTGAAATCTCGGGGGCCAAGTATGATATCGGGGCAATTCCATTCGGTGATCTGTTCGTCGCGGCC
GTGGCGACGGTGACAGGGTGGCTGATTGCACGGCTTCCTACCGGTCCGCTCGAGACAGCGATGCGACGCTTTGACCGGGC
ATTCAGCAATTTGGGACCCGTCACGGGACCGGCGAGACTGAGATAG

Upstream 100 bases:

>100_bases
GTTGATCAAACTTTAGCGACATCTGCCCGCTATATTGAATACAGCATGGCTTCACCTAAATATAGGAAAAGGATTAATTT
TTTTTTGAGGAGGAATACAG

Downstream 100 bases:

>100_bases
GCGGTCTTCAACATGTTGCCTGAAGGAACCGAGAGGCAGCTCCTTCAGGATTTTAGCCTGTCGAGAGGAATATGCAGTGG
ATGAGTTCATGCTGAACCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSIRIKLPDGSVREFEEEASIEDVAASISCGLEHAVAGKLNGKLVDLSTPLQDGALVEIVTRDSAEGQKIVREKSRGKGR
IVALDAARGLAVIGMYLQHFALNETNGSIVSGNTTLLFVLCGGISYSIMAGRMMDRGMEPAAFRTRMLARAVFIDMIGYL
LIMLNTPFGVILPAYAALFVLALVLIRRSTRVLVTTAAVLLAVSPPLMILGGSVLSGANLLGDIAGGPMSALALAPAFVA
GMAIGRFDLTRMRTALSLVSSGAVMLIVSKLLGVFVLPWLSRSFEEWLVSVQGTAGAEPDQYAIWPHNVAPPLWHNLLSI
APHSASTFQTMLGLGAAFLVLGMVCLVPQKISAVLKPFAGVGRVALTMYAAQFVVIWALEISGAKYDIGAIPFGDLFVAA
VATVTGWLIARLPTGPLETAMRRFDRAFSNLGPVTGPARLR

Sequences:

>Translated_441_residues
MSIRIKLPDGSVREFEEEASIEDVAASISCGLEHAVAGKLNGKLVDLSTPLQDGALVEIVTRDSAEGQKIVREKSRGKGR
IVALDAARGLAVIGMYLQHFALNETNGSIVSGNTTLLFVLCGGISYSIMAGRMMDRGMEPAAFRTRMLARAVFIDMIGYL
LIMLNTPFGVILPAYAALFVLALVLIRRSTRVLVTTAAVLLAVSPPLMILGGSVLSGANLLGDIAGGPMSALALAPAFVA
GMAIGRFDLTRMRTALSLVSSGAVMLIVSKLLGVFVLPWLSRSFEEWLVSVQGTAGAEPDQYAIWPHNVAPPLWHNLLSI
APHSASTFQTMLGLGAAFLVLGMVCLVPQKISAVLKPFAGVGRVALTMYAAQFVVIWALEISGAKYDIGAIPFGDLFVAA
VATVTGWLIARLPTGPLETAMRRFDRAFSNLGPVTGPARLR
>Mature_440_residues
SIRIKLPDGSVREFEEEASIEDVAASISCGLEHAVAGKLNGKLVDLSTPLQDGALVEIVTRDSAEGQKIVREKSRGKGRI
VALDAARGLAVIGMYLQHFALNETNGSIVSGNTTLLFVLCGGISYSIMAGRMMDRGMEPAAFRTRMLARAVFIDMIGYLL
IMLNTPFGVILPAYAALFVLALVLIRRSTRVLVTTAAVLLAVSPPLMILGGSVLSGANLLGDIAGGPMSALALAPAFVAG
MAIGRFDLTRMRTALSLVSSGAVMLIVSKLLGVFVLPWLSRSFEEWLVSVQGTAGAEPDQYAIWPHNVAPPLWHNLLSIA
PHSASTFQTMLGLGAAFLVLGMVCLVPQKISAVLKPFAGVGRVALTMYAAQFVVIWALEISGAKYDIGAIPFGDLFVAAV
ATVTGWLIARLPTGPLETAMRRFDRAFSNLGPVTGPARLR

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 46732; Mature: 46601

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRIKLPDGSVREFEEEASIEDVAASISCGLEHAVAGKLNGKLVDLSTPLQDGALVEIV
CEEEEECCCCCHHHHHHHCCHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCCCCEEEEE
TRDSAEGQKIVREKSRGKGRIVALDAARGLAVIGMYLQHFALNETNGSIVSGNTTLLFVL
ECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEE
CGGISYSIMAGRMMDRGMEPAAFRTRMLARAVFIDMIGYLLIMLNTPFGVILPAYAALFV
ECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LALVLIRRSTRVLVTTAAVLLAVSPPLMILGGSVLSGANLLGDIAGGPMSALALAPAFVA
HHHHHHHCCCHHHHHHHHHHHHCCCCHHEECCCHHCCHHHHHHCCCCCHHHHHHHHHHHH
GMAIGRFDLTRMRTALSLVSSGAVMLIVSKLLGVFVLPWLSRSFEEWLVSVQGTAGAEPD
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
QYAIWPHNVAPPLWHNLLSIAPHSASTFQTMLGLGAAFLVLGMVCLVPQKISAVLKPFAG
CEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGRVALTMYAAQFVVIWALEISGAKYDIGAIPFGDLFVAAVATVTGWLIARLPTGPLETA
HHHHHHHHHHHHHHHEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MRRFDRAFSNLGPVTGPARLR
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SIRIKLPDGSVREFEEEASIEDVAASISCGLEHAVAGKLNGKLVDLSTPLQDGALVEIV
EEEEECCCCCHHHHHHHCCHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCCCCEEEEE
TRDSAEGQKIVREKSRGKGRIVALDAARGLAVIGMYLQHFALNETNGSIVSGNTTLLFVL
ECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEE
CGGISYSIMAGRMMDRGMEPAAFRTRMLARAVFIDMIGYLLIMLNTPFGVILPAYAALFV
ECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LALVLIRRSTRVLVTTAAVLLAVSPPLMILGGSVLSGANLLGDIAGGPMSALALAPAFVA
HHHHHHHCCCHHHHHHHHHHHHCCCCHHEECCCHHCCHHHHHHCCCCCHHHHHHHHHHHH
GMAIGRFDLTRMRTALSLVSSGAVMLIVSKLLGVFVLPWLSRSFEEWLVSVQGTAGAEPD
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
QYAIWPHNVAPPLWHNLLSIAPHSASTFQTMLGLGAAFLVLGMVCLVPQKISAVLKPFAG
CEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGRVALTMYAAQFVVIWALEISGAKYDIGAIPFGDLFVAAVATVTGWLIARLPTGPLETA
HHHHHHHHHHHHHHHEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MRRFDRAFSNLGPVTGPARLR
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2115870; 8969504; 9387221; 9384377; 3027671; 1379177 [H]