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The map label for this gene is malP [H]

Identifier: 52784655

GI number: 52784655

Start: 876838

End: 878427

Strand: Direct

Name: malP [H]

Synonym: BLi00857

Alternate gene names: 52784655

Gene position: 876838-878427 (Clockwise)

Preceding gene: 52784654

Following gene: 52784659

Centisome position: 20.77

GC content: 47.67

Gene sequence:

>1590_bases
ATGCAAAAAGTACAGCGGTTCGGAAGCGCCATGTTTGTGCCGGTTTTGCTATTTGCTTTTGCCGGGATCGTCGTGGGCCT
CAGCACATTATTTAAGAATGAGCAGCTGATGGGATCGCTTGCCAGTCAGGATACCTTTTGGTATCAATTCTGGTATATCC
TTGAGGAAGGCGGCTGGACCGTTTTCAGGCAAATGCCGCTGTTGTTTGCGGTCGGAATTCCGATCGCACTGGCAAAAAAA
GCGCAAGCGCGGGCATGTTTGGAAGCGCTTACTACTTATTTGACCTTCAATTATTTTGTCAGCGCTATTTTGACTGTATG
GGGCGACTTTTTCGGAGTTGATATGACTCAGGAAGCAGGAGGAACAAGCGGGCTTGCAGAAATTGCCGGCATCAAAACCC
TTGATACGAACATTATCGGGGCGATTCTGATTTCATCGATTGTCGTTTATATCCACAACCGCTATTTTGATAAGAAGCTG
CCCGATTTTTTAGGGATTTTTCAAGGCTCTTCATTCGTCGTCATTATTTCATTTGCGATTATGCTTCCGGTAGCACTGGC
AACCGCGTGGATTTGGCCGATGGTGCAGGACGGCATTGCGTCGCTGCAAAGCTTCCTTGTCGCCTCAGGTGCTTTCGGTG
TATGGGTTTACACATTTTTAGAAAGAATTTTGATCCCTACGGGCCTGCATCACTTCATATACACGCCATTTGTTTTCGGC
CCGGCCGTAGTTGAAGGCGGGATTGTCACCTATTGGGCGCAGCATCTCAGCGAGTTTTCAGCAAGCTCTGAACCGTTGAA
AGAGCTCTTTCCTCAAGGCGGATTCGCGCTCCACGGAAACTCCAAAATCTTCGGAATTCTGGGGATCGCACTAGCCATCT
ATGTAACAGCCAAAAAAGAAAAGAAAAAAATCGTTGCCGGTCTGCTGATTCCGATCACGCTGACAGCGGTAATTGCGGGG
ATCACGGAGCCGATTGAATTTACGTTTTTGTTCATTTCGCCGCTGCTGTTTTTCGTACACAGCCTCTTGGCCGCGACGAT
GGCAACCTTGATGTATGCTGCAGGGGTGGTCGGAAATATGGGCGGCGGTTTAATCGAGATTTTAACGCTCAACTGGATCC
CTCTGTTTCATCAGCACGGCAGCACTTATGTTTTTCAAATTTTGATCGGCTTGTCTTTCACCGCCATTTACTTCTTCGTA
TTCAGGTTCTTGATTTTAAAATTGGATATTGCCACGCCGGGGCGTGAAAAAGACCAGCAGCAGGAGACAAAATTTTATTC
GAAAAAAGATTACAAGGCGAAAAAAGAATCCGAAAAAGAGGTTTCTGCGGCGCAGGAAATTGCTGAGACCGATCAGGCGG
TTCTTTGCATCAAAGCGCTCGGCGGAAAAGAAAACATTGCGGAGGTGACAAACTGCGCGACAAGACTGAGAGTCAGCGTG
TATGACGAGTCAAAAGTGGAGCCGGACAGTACGTTTAAGTCCTTTGGCGTTCACGGTGTCGTCAGAAACGGAAAAGCCTT
GCAAATTATTATCGGTCTTTCGGTTCCGCAAGTCCGTGAAAGGGTCGAGAAGCTGCTGAACCAATCATAA

Upstream 100 bases:

>100_bases
TTTTGCACCCTTTTTTCTCGTTGGGGAAGCGCTGTTTCGCAGCTATGTCGACTATGCTGAAGAAAAGAAAAATCAGGAGT
AACAGGGGGGATTCGCATTG

Downstream 100 bases:

>100_bases
TTGCGCCGGTGCAAATGGCATCTCCTGAAATGACACATGCAAGCTGCAGAGACTTGCATGTGCGATTGGGGGATGCTCTT
TTAATGCAAAGACAAGCTAA

Product: MalP

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MQKVQRFGSAMFVPVLLFAFAGIVVGLSTLFKNEQLMGSLASQDTFWYQFWYILEEGGWTVFRQMPLLFAVGIPIALAKK
AQARACLEALTTYLTFNYFVSAILTVWGDFFGVDMTQEAGGTSGLAEIAGIKTLDTNIIGAILISSIVVYIHNRYFDKKL
PDFLGIFQGSSFVVIISFAIMLPVALATAWIWPMVQDGIASLQSFLVASGAFGVWVYTFLERILIPTGLHHFIYTPFVFG
PAVVEGGIVTYWAQHLSEFSASSEPLKELFPQGGFALHGNSKIFGILGIALAIYVTAKKEKKKIVAGLLIPITLTAVIAG
ITEPIEFTFLFISPLLFFVHSLLAATMATLMYAAGVVGNMGGGLIEILTLNWIPLFHQHGSTYVFQILIGLSFTAIYFFV
FRFLILKLDIATPGREKDQQQETKFYSKKDYKAKKESEKEVSAAQEIAETDQAVLCIKALGGKENIAEVTNCATRLRVSV
YDESKVEPDSTFKSFGVHGVVRNGKALQIIIGLSVPQVRERVEKLLNQS

Sequences:

>Translated_529_residues
MQKVQRFGSAMFVPVLLFAFAGIVVGLSTLFKNEQLMGSLASQDTFWYQFWYILEEGGWTVFRQMPLLFAVGIPIALAKK
AQARACLEALTTYLTFNYFVSAILTVWGDFFGVDMTQEAGGTSGLAEIAGIKTLDTNIIGAILISSIVVYIHNRYFDKKL
PDFLGIFQGSSFVVIISFAIMLPVALATAWIWPMVQDGIASLQSFLVASGAFGVWVYTFLERILIPTGLHHFIYTPFVFG
PAVVEGGIVTYWAQHLSEFSASSEPLKELFPQGGFALHGNSKIFGILGIALAIYVTAKKEKKKIVAGLLIPITLTAVIAG
ITEPIEFTFLFISPLLFFVHSLLAATMATLMYAAGVVGNMGGGLIEILTLNWIPLFHQHGSTYVFQILIGLSFTAIYFFV
FRFLILKLDIATPGREKDQQQETKFYSKKDYKAKKESEKEVSAAQEIAETDQAVLCIKALGGKENIAEVTNCATRLRVSV
YDESKVEPDSTFKSFGVHGVVRNGKALQIIIGLSVPQVRERVEKLLNQS
>Mature_529_residues
MQKVQRFGSAMFVPVLLFAFAGIVVGLSTLFKNEQLMGSLASQDTFWYQFWYILEEGGWTVFRQMPLLFAVGIPIALAKK
AQARACLEALTTYLTFNYFVSAILTVWGDFFGVDMTQEAGGTSGLAEIAGIKTLDTNIIGAILISSIVVYIHNRYFDKKL
PDFLGIFQGSSFVVIISFAIMLPVALATAWIWPMVQDGIASLQSFLVASGAFGVWVYTFLERILIPTGLHHFIYTPFVFG
PAVVEGGIVTYWAQHLSEFSASSEPLKELFPQGGFALHGNSKIFGILGIALAIYVTAKKEKKKIVAGLLIPITLTAVIAG
ITEPIEFTFLFISPLLFFVHSLLAATMATLMYAAGVVGNMGGGLIEILTLNWIPLFHQHGSTYVFQILIGLSFTAIYFFV
FRFLILKLDIATPGREKDQQQETKFYSKKDYKAKKESEKEVSAAQEIAETDQAVLCIKALGGKENIAEVTNCATRLRVSV
YDESKVEPDSTFKSFGVHGVVRNGKALQIIIGLSVPQVRERVEKLLNQS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=542, Percent_Identity=28.7822878228782, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1787343, Length=534, Percent_Identity=29.2134831460674, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1786894, Length=532, Percent_Identity=28.9473684210526, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 58302; Mature: 58302

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCCCCCCCHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure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ECCCCCCCCHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]