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The map label for this gene is yfkJ [H]

Identifier: 52784617

GI number: 52784617

Start: 839116

End: 839586

Strand: Direct

Name: yfkJ [H]

Synonym: BLi00818

Alternate gene names: 52784617

Gene position: 839116-839586 (Clockwise)

Preceding gene: 52784614

Following gene: 52784618

Centisome position: 19.87

GC content: 50.53

Gene sequence:

>471_bases
ATGATCAAAGTGTTATTTGTCTGCCTCGGCAATATTTGCCGATCTCCGATGGCAGAAGCTGTATTTAACGATATGCTCAA
AAAAAGCGGACTGGAGGACCGGATCGAAGCCGATTCGGCTGGCACAGGAAGCTGGCATGTCGGCAAACCGCCTCATGAAG
GCACAAGGTCGCTGCTGTCTGAAAAAAAGATAAGCTGCGAAGGCCTGTATGCAAGGCAGATTACTGACAAGGACCCGGAA
GCGTTCGATTATATCATCGCAATGGATGCCGAAAATGCAGGCCATGTGAGAAGCCTTGCCGGCTACGGGAGCAAAGCCGT
CATCCGGAGGCTGCTCGACTATGTCGAAGACTGTGAGACGGCAGATGTTCCTGATCCATACTACACCGGGAACTTTGAAG
AGGTGTACGAACTCGTCGCGAAAGGGTGCCGCGAATTGCTGAAGGACATTCGAAAAGAACACAATCTATAA

Upstream 100 bases:

>100_bases
TCTTCCCAAAGTTGAAAAAAACAGAAAAATCTTTAGTATAAAAGCAAAAGTGTTTTTTCTTTCTGAAAAGTGGGGAAAGA
ATAGAGGAGGCTCCTGAGTG

Downstream 100 bases:

>100_bases
AAACGAAGGGAGAGATTTTTTATGAAAAACGACCGCGTTTTCATCAGAAATATCCTCCTCGGCGCTTCGGTCGGGGCGGT
TATGTCACTGCTGCACAAAC

Product: YfkJ

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MIKVLFVCLGNICRSPMAEAVFNDMLKKSGLEDRIEADSAGTGSWHVGKPPHEGTRSLLSEKKISCEGLYARQITDKDPE
AFDYIIAMDAENAGHVRSLAGYGSKAVIRRLLDYVEDCETADVPDPYYTGNFEEVYELVAKGCRELLKDIRKEHNL

Sequences:

>Translated_156_residues
MIKVLFVCLGNICRSPMAEAVFNDMLKKSGLEDRIEADSAGTGSWHVGKPPHEGTRSLLSEKKISCEGLYARQITDKDPE
AFDYIIAMDAENAGHVRSLAGYGSKAVIRRLLDYVEDCETADVPDPYYTGNFEEVYELVAKGCRELLKDIRKEHNL
>Mature_156_residues
MIKVLFVCLGNICRSPMAEAVFNDMLKKSGLEDRIEADSAGTGSWHVGKPPHEGTRSLLSEKKISCEGLYARQITDKDPE
AFDYIIAMDAENAGHVRSLAGYGSKAVIRRLLDYVEDCETADVPDPYYTGNFEEVYELVAKGCRELLKDIRKEHNL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=149, Percent_Identity=38.255033557047, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI6005988, Length=149, Percent_Identity=38.255033557047, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=36.3636363636364, Blast_Score=94, Evalue=9e-21,
Organism=Drosophila melanogaster, GI78706766, Length=150, Percent_Identity=40, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI78706768, Length=150, Percent_Identity=40, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI78706770, Length=151, Percent_Identity=37.7483443708609, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI78706772, Length=151, Percent_Identity=37.7483443708609, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=43.0769230769231, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI78711846, Length=158, Percent_Identity=34.8101265822785, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648069, Length=87, Percent_Identity=40.2298850574713, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17431; Mature: 17431

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVLFVCLGNICRSPMAEAVFNDMLKKSGLEDRIEADSAGTGSWHVGKPPHEGTRSLLS
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
EKKISCEGLYARQITDKDPEAFDYIIAMDAENAGHVRSLAGYGSKAVIRRLLDYVEDCET
HHCCCCCHHHHHHCCCCCCCHHHEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCC
ADVPDPYYTGNFEEVYELVAKGCRELLKDIRKEHNL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKVLFVCLGNICRSPMAEAVFNDMLKKSGLEDRIEADSAGTGSWHVGKPPHEGTRSLLS
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
EKKISCEGLYARQITDKDPEAFDYIIAMDAENAGHVRSLAGYGSKAVIRRLLDYVEDCET
HHCCCCCHHHHHHCCCCCCCHHHEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCC
ADVPDPYYTGNFEEVYELVAKGCRELLKDIRKEHNL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]