Click here to switch to the map view.

The map label for this gene is treP [H]

Identifier: 52784595

GI number: 52784595

Start: 806433

End: 807845

Strand: Direct

Name: treP [H]

Synonym: BLi00796

Alternate gene names: 52784595

Gene position: 806433-807845 (Clockwise)

Preceding gene: 52784594

Following gene: 52784596

Centisome position: 19.1

GC content: 49.19

Gene sequence:

>1413_bases
ATGACTGATTTGAATCAATCAGCGCGACGGATTGTCGATGCTGTCGGCGGTGCTGACAACATTGCAGCGGTAACCCATTG
TGTAACGCGTTTGCGATTTGCATTGCTCGATGAAAGCAAAGTCAATCAAGAGGTGCTGGAGCAAATAGATGTTGTCAAAG
GATCGTTTTCGACTAACGGCCAATTTCAAGTGGTGATCGGCCAAGGAACGGTCAACAATGTGTACGCGGAGCTGGTGAAG
GCAACAGGAATCGGCGAATCGTCAAAGGATGATGTTAAGAAAGCCTCAGAGAAAAATATGAATCCTTTACAGCGTGCCGT
GAAAACGCTTGCAGATATATTTATTCCAATATTGCCGGCGATTGTCACTGCCGGGCTGCTGATGGGGATCAACAATATCC
TGACGGCTCAAGACATTTTCTTCAGCGGAAAATCAATCGTTGAAGTCTATCCGCAATGGGCGGATCTCGCTAATATGATT
AACTTGATCGCGGGGACTGCTTTCGCATTTCTCCCTGCGCTAATCGGCTGGTCGGCCGTCAAGCGGTTTGGCGGAAATCC
GCTGCTCGGCATCGTGCTCGGCGTCATGCTTGTGCACCCTGATTTGTTAAACGCCTGGGGATACGGGGCTGCGGAGCAAA
GCGGAGAGATTCCTGTCTGGAATTTATTCGGTTTGGAAGTGCAGAAGGTCGGCTACCAGGGGCAGGTGCTTCCCATTTTG
CTCGCTTCTTATTTGCTGGCAAAAATTGAGCGCTTTTTGACAAAGCGGACGCCTGAGAGCATTCAGCTCCTTGTTGTGGC
ACCGATTACGCTGCTTGTCACAGGTTTTGCTTCATTTATTGTCCTTGGACCGATTACATTTGCCATCGGAAATGTTTTAA
CATCAGGCCTTATTGCTGTCTTTGAACAATTCGCCGTACTGGGCGGACTGTTATACGGAGGGCTTTACGCCGCTCTCGTC
ATTACCGGAATGCATCATACATTCCTTGCCGTTGACCTTCAGCTGATCGGCTCAAAGCTCGGCGGAACATTTTTATGGCC
GATGCTCGCGCTGTCCAATATTGCACAAGGTTCAGCCGCGCTTGCGATGATGTTTATTGTCAAAGATGAGAAGCAGAAAG
GCCTGTCCCTGACATCCGGAATTTCAGCTTATCTCGGAATTACCGAACCGGCATTGTTCGGAGTGAATCTCAGATACAGA
TTTCCGTTCGTGATCGCGATGATCAGTTCGGGGATTGCCGGTATGTTCATTTCCTCGCAAGGGGTTTTGGCAAGCTCTGT
CGGCGTCGGCGGCGTACCTGGAATTTTCTCTATTATGAGCCAATACTGGGGAGCGTTTGCGATCGGAATGGCGATCGTGT
TGATCGCGCCGTTTGCCGGAACATATCTCTACGCAAAATTAAAAATGAAATAA

Upstream 100 bases:

>100_bases
TGAAAGCGCTACAAAAATATATTGACTACTTGTATATACAGGAATACAATAAACCTATAACATGTATATACAGGTTATAA
GAGGAGAAGGAGGGATTGGA

Downstream 100 bases:

>100_bases
GAGAGGGAGAGGGGCGCGCATATTTGTCTGCCCTTTTCCCATTTTCATAAAGAAGAAAGCGGTGGTGTTGAAAATGGAAA
CGAAAGAAAATCCATGGTGG

Product: TreP

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTDLNQSARRIVDAVGGADNIAAVTHCVTRLRFALLDESKVNQEVLEQIDVVKGSFSTNGQFQVVIGQGTVNNVYAELVK
ATGIGESSKDDVKKASEKNMNPLQRAVKTLADIFIPILPAIVTAGLLMGINNILTAQDIFFSGKSIVEVYPQWADLANMI
NLIAGTAFAFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
LASYLLAKIERFLTKRTPESIQLLVVAPITLLVTGFASFIVLGPITFAIGNVLTSGLIAVFEQFAVLGGLLYGGLYAALV
ITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPALFGVNLRYR
FPFVIAMISSGIAGMFISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIAPFAGTYLYAKLKMK

Sequences:

>Translated_470_residues
MTDLNQSARRIVDAVGGADNIAAVTHCVTRLRFALLDESKVNQEVLEQIDVVKGSFSTNGQFQVVIGQGTVNNVYAELVK
ATGIGESSKDDVKKASEKNMNPLQRAVKTLADIFIPILPAIVTAGLLMGINNILTAQDIFFSGKSIVEVYPQWADLANMI
NLIAGTAFAFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
LASYLLAKIERFLTKRTPESIQLLVVAPITLLVTGFASFIVLGPITFAIGNVLTSGLIAVFEQFAVLGGLLYGGLYAALV
ITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPALFGVNLRYR
FPFVIAMISSGIAGMFISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIAPFAGTYLYAKLKMK
>Mature_469_residues
TDLNQSARRIVDAVGGADNIAAVTHCVTRLRFALLDESKVNQEVLEQIDVVKGSFSTNGQFQVVIGQGTVNNVYAELVKA
TGIGESSKDDVKKASEKNMNPLQRAVKTLADIFIPILPAIVTAGLLMGINNILTAQDIFFSGKSIVEVYPQWADLANMIN
LIAGTAFAFLPALIGWSAVKRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPILL
ASYLLAKIERFLTKRTPESIQLLVVAPITLLVTGFASFIVLGPITFAIGNVLTSGLIAVFEQFAVLGGLLYGGLYAALVI
TGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAALAMMFIVKDEKQKGLSLTSGISAYLGITEPALFGVNLRYRF
PFVIAMISSGIAGMFISSQGVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIAPFAGTYLYAKLKMK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=456, Percent_Identity=42.7631578947368, Blast_Score=355, Evalue=4e-99,
Organism=Escherichia coli, GI1790159, Length=443, Percent_Identity=31.8284424379233, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI48994906, Length=463, Percent_Identity=27.4298056155508, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788769, Length=420, Percent_Identity=27.3809523809524, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 49970; Mature: 49838

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLNQSARRIVDAVGGADNIAAVTHCVTRLRFALLDESKVNQEVLEQIDVVKGSFSTNG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCCCCC
QFQVVIGQGTVNNVYAELVKATGIGESSKDDVKKASEKNMNPLQRAVKTLADIFIPILPA
EEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNILTAQDIFFSGKSIVEVYPQWADLANMINLIAGTAFAFLPALIGWSAV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
HHCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEEECCCHHHCCCCCCHHHHH
LASYLLAKIERFLTKRTPESIQLLVVAPITLLVTGFASFIVLGPITFAIGNVLTSGLIAV
HHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQFAVLGGLLYGGLYAALVITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHH
LAMMFIVKDEKQKGLSLTSGISAYLGITEPALFGVNLRYRFPFVIAMISSGIAGMFISSQ
HHHHHHEECCHHCCCCHHHCHHHHHCCCCCHHEECEEEEHHHHHHHHHHCCHHEEEECCC
GVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIAPFAGTYLYAKLKMK
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
>Mature Secondary Structure 
TDLNQSARRIVDAVGGADNIAAVTHCVTRLRFALLDESKVNQEVLEQIDVVKGSFSTNG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCCCCC
QFQVVIGQGTVNNVYAELVKATGIGESSKDDVKKASEKNMNPLQRAVKTLADIFIPILPA
EEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IVTAGLLMGINNILTAQDIFFSGKSIVEVYPQWADLANMINLIAGTAFAFLPALIGWSAV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRFGGNPLLGIVLGVMLVHPDLLNAWGYGAAEQSGEIPVWNLFGLEVQKVGYQGQVLPIL
HHCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEEECCCHHHCCCCCCHHHHH
LASYLLAKIERFLTKRTPESIQLLVVAPITLLVTGFASFIVLGPITFAIGNVLTSGLIAV
HHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQFAVLGGLLYGGLYAALVITGMHHTFLAVDLQLIGSKLGGTFLWPMLALSNIAQGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHH
LAMMFIVKDEKQKGLSLTSGISAYLGITEPALFGVNLRYRFPFVIAMISSGIAGMFISSQ
HHHHHHEECCHHCCCCHHHCHHHHHCCCCCHHEECEEEEHHHHHHHHHHCCHHEEEECCC
GVLASSVGVGGVPGIFSIMSQYWGAFAIGMAIVLIAPFAGTYLYAKLKMK
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129 [H]