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The map label for this gene is yciA

Identifier: 52784561

GI number: 52784561

Start: 772325

End: 773227

Strand: Reverse

Name: yciA

Synonym: BLi00762

Alternate gene names: 52784561

Gene position: 773227-772325 (Counterclockwise)

Preceding gene: 52784571

Following gene: 52784539

Centisome position: 18.31

GC content: 49.17

Gene sequence:

>903_bases
ATGGAACGCAAACTGCATTTGCCCGCAAAACCCGAACGCCACCGCCGCTTCGGATCTGTCGAAGCCGTGAAAGGAATAAA
ACCGACTGATAAAGAACAGATGAAGGATATTCAAAATACACCGAACGACTATTTTTTTGACATTGACCATGTCGGTGTCT
CAAACGTTTCGCATCCGATTTTGATTGCTTCCTCGCTCAAGCCGTTTACACAAACGACGATCGGCGCTTTTTCCTTTACG
ACGAGCCTTGCGCGCGACCGCAAAGGAATCAATATGAGCCGCCTGACAGAACAGCTGCAGCGCTATCACGAAGCAAACTG
GACGGTTGACTTCCATACACTGAAAGATTTTGCAAAGGATTTAGCCGGCAATATGGAACAGGAAAGCGCATCCGTCTCCG
TCAGTTTTCCATGGTATTTCGAACGCATCAGCCCGGAAACCAAATTGTCCGGACTGATGCATGCCGATATCCATATGACA
GTCTCTTATCATGAAAACAAAGGCTTTTCGCAAACCGCCGGCATCACCGCCCATGCGACGACGCTCTGCCCTTGTTCAAA
AGAAATCAGCGAATACAGCGCCCATAACCAGCGCGGCATAATCAAGATCACCGCGCATATCAATGAACAGGCGGAGATGC
CGGACGATTTCAAAGCCGAGCTTCTTGCCGCAGCGGAAACGAACGCAAGCGCAAAGCTCCATCCCGTCTTAAAAAGACCC
GATGAAAAGAGAGTGACTGAACAGGCTTATGAGAATCCAAGATTTGTAGAAGACGTCCTCCGCTTAACAGCTGCCGACTT
ATACGAAATGGACTGGATCTCCGCCTTTGAGATCGAATGCCGGAACGAAGAATCGATTCACTTGCACGATGCCGTGGCGC
GGCTATCGTTTTCCAAATGTTAA

Upstream 100 bases:

>100_bases
TTAATTTGCATGCTTTAGACATGACCACTTGATTTTATCACAGCATTGCCTCAAAATAAATAGGAACTATTTCGATTTAC
TGAAGAAAGGGGTCTCATCA

Downstream 100 bases:

>100_bases
AAAGCTCGGCCGAAAAAATGGCCGAGCTTTACAATTTTAATGATGAGCGTGGTCAAGCAGACGATGCTGAACATCATAAA
GAATGCCAGCGAGCCTCTTC

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MERKLHLPAKPERHRRFGSVEAVKGIKPTDKEQMKDIQNTPNDYFFDIDHVGVSNVSHPILIASSLKPFTQTTIGAFSFT
TSLARDRKGINMSRLTEQLQRYHEANWTVDFHTLKDFAKDLAGNMEQESASVSVSFPWYFERISPETKLSGLMHADIHMT
VSYHENKGFSQTAGITAHATTLCPCSKEISEYSAHNQRGIIKITAHINEQAEMPDDFKAELLAAAETNASAKLHPVLKRP
DEKRVTEQAYENPRFVEDVLRLTAADLYEMDWISAFEIECRNEESIHLHDAVARLSFSKC

Sequences:

>Translated_300_residues
MERKLHLPAKPERHRRFGSVEAVKGIKPTDKEQMKDIQNTPNDYFFDIDHVGVSNVSHPILIASSLKPFTQTTIGAFSFT
TSLARDRKGINMSRLTEQLQRYHEANWTVDFHTLKDFAKDLAGNMEQESASVSVSFPWYFERISPETKLSGLMHADIHMT
VSYHENKGFSQTAGITAHATTLCPCSKEISEYSAHNQRGIIKITAHINEQAEMPDDFKAELLAAAETNASAKLHPVLKRP
DEKRVTEQAYENPRFVEDVLRLTAADLYEMDWISAFEIECRNEESIHLHDAVARLSFSKC
>Mature_300_residues
MERKLHLPAKPERHRRFGSVEAVKGIKPTDKEQMKDIQNTPNDYFFDIDHVGVSNVSHPILIASSLKPFTQTTIGAFSFT
TSLARDRKGINMSRLTEQLQRYHEANWTVDFHTLKDFAKDLAGNMEQESASVSVSFPWYFERISPETKLSGLMHADIHMT
VSYHENKGFSQTAGITAHATTLCPCSKEISEYSAHNQRGIIKITAHINEQAEMPDDFKAELLAAAETNASAKLHPVLKRP
DEKRVTEQAYENPRFVEDVLRLTAADLYEMDWISAFEIECRNEESIHLHDAVARLSFSKC

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_BACLD (Q65ML7)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_077985.1
- RefSeq:   YP_090390.1
- ProteinModelPortal:   Q65ML7
- SMR:   Q65ML7
- STRING:   Q65ML7
- EnsemblBacteria:   EBBACT00000055492
- EnsemblBacteria:   EBBACT00000059169
- GeneID:   3031477
- GeneID:   3098927
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00762
- KEGG:   bli:BL02349
- NMPDR:   fig|279010.5.peg.1112
- eggNOG:   COG1469
- GeneTree:   EBGT00050000006260
- HOGENOM:   HBG626871
- OMA:   SLMDYEV
- ProtClustDB:   PRK13674
- BioCyc:   BLIC279010-1:BLI00762-MONOMER
- BioCyc:   BLIC279010:BL02349-MONOMER
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 34081; Mature: 34081

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKLHLPAKPERHRRFGSVEAVKGIKPTDKEQMKDIQNTPNDYFFDIDHVGVSNVSHPI
CCCCCCCCCCCHHHHHCCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCE
LIASSLKPFTQTTIGAFSFTTSLARDRKGINMSRLTEQLQRYHEANWTVDFHTLKDFAKD
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
LAGNMEQESASVSVSFPWYFERISPETKLSGLMHADIHMTVSYHENKGFSQTAGITAHAT
HHCCCCCCCCEEEEECCHHHHHCCCHHHHCCEEEEEEEEEEEEECCCCCCHHCCCEEEEE
TLCPCSKEISEYSAHNQRGIIKITAHINEQAEMPDDFKAELLAAAETNASAKLHPVLKRP
EECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEECHHHCCC
DEKRVTEQAYENPRFVEDVLRLTAADLYEMDWISAFEIECRNEESIHLHDAVARLSFSKC
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure
MERKLHLPAKPERHRRFGSVEAVKGIKPTDKEQMKDIQNTPNDYFFDIDHVGVSNVSHPI
CCCCCCCCCCCHHHHHCCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCE
LIASSLKPFTQTTIGAFSFTTSLARDRKGINMSRLTEQLQRYHEANWTVDFHTLKDFAKD
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
LAGNMEQESASVSVSFPWYFERISPETKLSGLMHADIHMTVSYHENKGFSQTAGITAHAT
HHCCCCCCCCEEEEECCHHHHHCCCHHHHCCEEEEEEEEEEEEECCCCCCHHCCCEEEEE
TLCPCSKEISEYSAHNQRGIIKITAHINEQAEMPDDFKAELLAAAETNASAKLHPVLKRP
EECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEECHHHCCC
DEKRVTEQAYENPRFVEDVLRLTAADLYEMDWISAFEIECRNEESIHLHDAVARLSFSKC
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA