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The map label for this gene is ycnB [H]

Identifier: 52784287

GI number: 52784287

Start: 469829

End: 471250

Strand: Reverse

Name: ycnB [H]

Synonym: BLi00467

Alternate gene names: 52784287

Gene position: 471250-469829 (Counterclockwise)

Preceding gene: 52784288

Following gene: 52784282

Centisome position: 11.16

GC content: 50.14

Gene sequence:

>1422_bases
ATGAGTACAGGAACTGAACAACAGACATACAACAGAAATATCATCGTAGGTTTGCTTATTGCCGGGGCGTTTATCGCGAT
CTTGAACCAAACGCTCCTGGTTACCGCACTGCCGCATATTATGGCAGACTTGAACATAGACGCTACAAAAGCTCAATGGC
TGACAACGGCGTTCATGCTGACAAACGGGATTCTCATTCCGATTACCGCCTTTTTGATCGAAAAATTCTCGAGCCGCGCG
CTCGTCATCGCGGCGATGAGCATCTTTGCGGCGGGAACAGTCGTCGGTGCGGTGGCGCCTAACTTTCCGGTTCTTCTGGC
GGCGCGGATCATTCAGGCCGCAGGCGCCGGAATTATGATGCCGCTCATGCAGACGATCTTTTTAACGATTTTCCCGGTTG
AAAAACGCGGGGCTGCAATGGGCATGGTCGGCTTGGTGATCGCATTTGCACCGGCCATCGGACCGACATTGTCAGGCTGG
ATCGTCGACAGCTTTACATGGAGATACTTATTTTATATTATTCTGCCAATTGCACTGATTGATCTTGTGCTTGTCATCTT
GCTGATGAAAAACGTCACGAAATTGAGAGAAACATCAGTGGACATCATATCTATTATCCTGTCCAGCCTGGGTTTCGGCG
GTTTATTGTACGGCTTCAGCAACGCCGGATCAGAAGGCTGGGGGAGCAATACTGTTTTAATTTCCTTTGCAGTCGGTGCG
GTCGCCCTGTTCTTCTTTATCTCTAGACAATTGAAAATCAAAAGGCCGATACTCGAGTTTCGCGTTTTCCAATCGTGGAC
TTTTACGATAACAACGCTACTTGGTATGATCGTTTTTGCATTAATGATCGGTACTGAGACCATTTTGCCGCTGTACACGC
AAAACGTCAGAGACGTGACAGCTTTCGATTCGGGTTTGATGCTTCTGCCGGGCGCGATAGCAATGGGCATCATGTCGCCG
ATCATCGGCCGGATTTTTGACAAGATCGGCGGAAAAGGCCTTGCGATTATCGGGTTTGCCGTCTTGCTGCTGACGTCCAT
CCCGTTTGCGGACCTGCAAATGGATACTTCGCTGACATTTATTATCGTCATTTATACGCTGCGGATGATGGGAACTTCCA
TGATTATGATGCCTCTCACAACGGCGGGCATCAATGCCCTTCCGGCGCACCTCATTCCGCACGGAACAGCGATGAACAAT
ACGATGCGCCAGATCGGCGGTTCGATCGGCACGGCTGTTCTGATTTCCGTCATGAGTAATTCAGCCAAAAACGCCGCGAC
ATCTCATCCGTTAAATGCGCTCATTCACGGCATGAATTCCGCCTTTATCGTGGCCGCTGTCTTGGCGCTGATCGGATTTA
TCCTTTCGTTTACATTGAAAAAGAAGCCGCAGGCCGACAAACAAGGCCAGCCGGCCCGCTGA

Upstream 100 bases:

>100_bases
TAATTAAGGCTCTCCTTGATTACCTTGGAAAAATCGAGGCCATCCAATACGATGTTTCACAAATACAAACGATTAGTATA
AAAGAATAAGAGGGATTGAT

Downstream 100 bases:

>100_bases
TCATGTCACGCCAGTTCAATCGAACTGGCGTGTTTTTTTATATTCGCTTAACTGAGTCTGGGGCCCTTGCGGCGTTATGA
GCATGAAAACCCGCTTTGCA

Product: YcnB

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSTGTEQQTYNRNIIVGLLIAGAFIAILNQTLLVTALPHIMADLNIDATKAQWLTTAFMLTNGILIPITAFLIEKFSSRA
LVIAAMSIFAAGTVVGAVAPNFPVLLAARIIQAAGAGIMMPLMQTIFLTIFPVEKRGAAMGMVGLVIAFAPAIGPTLSGW
IVDSFTWRYLFYIILPIALIDLVLVILLMKNVTKLRETSVDIISIILSSLGFGGLLYGFSNAGSEGWGSNTVLISFAVGA
VALFFFISRQLKIKRPILEFRVFQSWTFTITTLLGMIVFALMIGTETILPLYTQNVRDVTAFDSGLMLLPGAIAMGIMSP
IIGRIFDKIGGKGLAIIGFAVLLLTSIPFADLQMDTSLTFIIVIYTLRMMGTSMIMMPLTTAGINALPAHLIPHGTAMNN
TMRQIGGSIGTAVLISVMSNSAKNAATSHPLNALIHGMNSAFIVAAVLALIGFILSFTLKKKPQADKQGQPAR

Sequences:

>Translated_473_residues
MSTGTEQQTYNRNIIVGLLIAGAFIAILNQTLLVTALPHIMADLNIDATKAQWLTTAFMLTNGILIPITAFLIEKFSSRA
LVIAAMSIFAAGTVVGAVAPNFPVLLAARIIQAAGAGIMMPLMQTIFLTIFPVEKRGAAMGMVGLVIAFAPAIGPTLSGW
IVDSFTWRYLFYIILPIALIDLVLVILLMKNVTKLRETSVDIISIILSSLGFGGLLYGFSNAGSEGWGSNTVLISFAVGA
VALFFFISRQLKIKRPILEFRVFQSWTFTITTLLGMIVFALMIGTETILPLYTQNVRDVTAFDSGLMLLPGAIAMGIMSP
IIGRIFDKIGGKGLAIIGFAVLLLTSIPFADLQMDTSLTFIIVIYTLRMMGTSMIMMPLTTAGINALPAHLIPHGTAMNN
TMRQIGGSIGTAVLISVMSNSAKNAATSHPLNALIHGMNSAFIVAAVLALIGFILSFTLKKKPQADKQGQPAR
>Mature_472_residues
STGTEQQTYNRNIIVGLLIAGAFIAILNQTLLVTALPHIMADLNIDATKAQWLTTAFMLTNGILIPITAFLIEKFSSRAL
VIAAMSIFAAGTVVGAVAPNFPVLLAARIIQAAGAGIMMPLMQTIFLTIFPVEKRGAAMGMVGLVIAFAPAIGPTLSGWI
VDSFTWRYLFYIILPIALIDLVLVILLMKNVTKLRETSVDIISIILSSLGFGGLLYGFSNAGSEGWGSNTVLISFAVGAV
ALFFFISRQLKIKRPILEFRVFQSWTFTITTLLGMIVFALMIGTETILPLYTQNVRDVTAFDSGLMLLPGAIAMGIMSPI
IGRIFDKIGGKGLAIIGFAVLLLTSIPFADLQMDTSLTFIIVIYTLRMMGTSMIMMPLTTAGINALPAHLIPHGTAMNNT
MRQIGGSIGTAVLISVMSNSAKNAATSHPLNALIHGMNSAFIVAAVLALIGFILSFTLKKKPQADKQGQPAR

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=427, Percent_Identity=27.6346604215457, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788710, Length=422, Percent_Identity=26.7772511848341, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081983, Length=418, Percent_Identity=25.5980861244019, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790195, Length=313, Percent_Identity=27.7955271565495, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788392, Length=399, Percent_Identity=25.31328320802, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323735, Length=318, Percent_Identity=23.5849056603774, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325455, Length=359, Percent_Identity=19.4986072423398, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=163, Percent_Identity=26.9938650306748, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50561; Mature: 50429

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGTEQQTYNRNIIVGLLIAGAFIAILNQTLLVTALPHIMADLNIDATKAQWLTTAFML
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TNGILIPITAFLIEKFSSRALVIAAMSIFAAGTVVGAVAPNFPVLLAARIIQAAGAGIMM
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHH
PLMQTIFLTIFPVEKRGAAMGMVGLVIAFAPAIGPTLSGWIVDSFTWRYLFYIILPIALI
HHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DLVLVILLMKNVTKLRETSVDIISIILSSLGFGGLLYGFSNAGSEGWGSNTVLISFAVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEHHHHHH
VALFFFISRQLKIKRPILEFRVFQSWTFTITTLLGMIVFALMIGTETILPLYTQNVRDVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
AFDSGLMLLPGAIAMGIMSPIIGRIFDKIGGKGLAIIGFAVLLLTSIPFADLQMDTSLTF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCEECCHHHH
IIVIYTLRMMGTSMIMMPLTTAGINALPAHLIPHGTAMNNTMRQIGGSIGTAVLISVMSN
HHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
SAKNAATSHPLNALIHGMNSAFIVAAVLALIGFILSFTLKKKPQADKQGQPAR
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
STGTEQQTYNRNIIVGLLIAGAFIAILNQTLLVTALPHIMADLNIDATKAQWLTTAFML
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH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CCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]