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The map label for this gene is tlpA [C]

Identifier: 52784281

GI number: 52784281

Start: 462561

End: 464279

Strand: Reverse

Name: tlpA [C]

Synonym: BLi00461

Alternate gene names: 52784281

Gene position: 464279-462561 (Counterclockwise)

Preceding gene: 52784282

Following gene: 52784278

Centisome position: 10.99

GC content: 45.61

Gene sequence:

>1719_bases
ATGAATCTGTTGAGAAATATAAAAATCAGAAGCAAACTGTTTGTCATCATTATCATTTCGGCGCTGGCTTTGTCAATTGT
AGGCATCCAGGGGGTAGGCGGGCTGAGCAAGCTTTCCAAAGGTTCCGAGATGATCTATCAAGATCAATTGATTCCCAACC
AGTTGTTTGCAAGATTAAAAGCGAACAACCTCGATCTTGATACGTACAAATTCGAGTTAATGGTGACGAAAGACAGCGAT
CGAAATGAAACTTTGCAAAAAAACATCAAGGAAAAAAACGAAGAAAACAACACCTTAATGGAAAAGATCGATCAGCTGAA
ATTAATGGACAACGTCTCTGAAAAATACGAGAGCTTCAAAAGCGAATACAAGAAATTGCAAGATATCAGCAGCCAGATGC
TCAGCTTGGCGGTGAAGAACGAAAATGACAAAGCTTATGATGTCTATCTAAAAGAGATGGAGCCTCAAAGAGAAACGGTC
AACCAGCTGATTGAAGACATTCAAACGCTAAATGCTGACAACGCCAAAACGATCTATCAGCGGGATTCTAAAGAAGCCGG
TTCCATCATCACGCTTCTCATCATTGTGATCGCAGCATCGCTTGTTTTATCCATCTCGATCGGACTCTTAATGACAAGGC
TGATCACAAAGCCGATCAAAGACATTCAGGCGCTGTTCGCAGAAACAGAGCAAGGCGATTTTACTGTCAAAGGAACATAT
CAATCGAAGGATGAATTGGGATTGCTGACCGCATCGTTTAACAAAATGGTAGCAGGCGTCCGTTCGATCATTGAAACGGT
CGGCGAAACGTCCCACCAAGTTGCTTCATCATCACAAGAATTGAGCGCCAGCGCTGATGAAAGCACAAAGGCGAGCGAGT
ACATCTCAACGACGATCCAGGAGCTTGCGGTAGGCTCTGATCAGCAGGTGGAAAGCGTTGAAAACAGCAGAACCGTTATT
AAGGGAATGACCGAGTTTGCCGGAAGAATTTCTTCTAGCGCCGAAAAGGCAGCCGCCACCGCAGACCAGACGGCGAAGAT
GTCGCTTGAAGGCACGAAAGCCATTGATAAAGTGAGCGCACAAATGCAGTCTATTAATGAAACGGTCGTTTCTCTTTCAG
AAGCATTTAAACATTTAACAGAACGTTCAAATGAGATCGGGAATATTACCGAAGTGATTACGAGCATCGCTGAACAAACG
AACCTGCTAGCTTTAAACGCGGCCATTGAAGCGGCCAGGGCTGGAGAACAAGGAAAAGGCTTTGCCGTCGTCGCGGATGA
AGTCAGAAAATTAGCCGAGCAATCGGCCCAGTCAGCAGAACAGATTACAAGGTTGATTACGATCATTCAAAACGATACAA
AGCAGACGATGAACTCGGTCATTTCGGCAACCGGCGAAGTCAAAGAAGGACTTGTCGTCGTTCATGAAGCCGGAGGCGCT
TTCCAAAAAATCGAAAACTCGATAACTGAGGTTGTCACACAGATCAATGATGTGACAAACTTGGTGAAAAACCTGACAGC
CGGCACAAGCGAAATCGAAACCGCGATTTCCGGCGTCAAAGAAGTAGCCGAGACTGCAGCGGGAAGCACGCAAACGGTTA
GTGCGGCAACCCAGGAGCAGCTTGCTTCAATGGAAGAAATCGCCGCCGCATCACAGATCCTCGCGCAAAACGCCGAAGAG
CTGCAGCACCTGATTCAGAAATTCAAAATTAAAGATTAA

Upstream 100 bases:

>100_bases
GAAAATGTCCCCTTCCCTTAAATTGCCTGCCCTAAATTGATTCACAAAACCGTTTTGAAAGCCGATATGTAAAGTAAATA
AATTGATGGGAGAACACCAT

Downstream 100 bases:

>100_bases
CAAAAACCCGCCAGACGCTGTCTGGCGGGTTTCTATTCATCATCATCTCTCGCCGTCAGCGGCAGGCGGATGATAAATTT
TGTTCCTTTGTTTTTCTCGC

Product: TlpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MNLLRNIKIRSKLFVIIIISALALSIVGIQGVGGLSKLSKGSEMIYQDQLIPNQLFARLKANNLDLDTYKFELMVTKDSD
RNETLQKNIKEKNEENNTLMEKIDQLKLMDNVSEKYESFKSEYKKLQDISSQMLSLAVKNENDKAYDVYLKEMEPQRETV
NQLIEDIQTLNADNAKTIYQRDSKEAGSIITLLIIVIAASLVLSISIGLLMTRLITKPIKDIQALFAETEQGDFTVKGTY
QSKDELGLLTASFNKMVAGVRSIIETVGETSHQVASSSQELSASADESTKASEYISTTIQELAVGSDQQVESVENSRTVI
KGMTEFAGRISSSAEKAAATADQTAKMSLEGTKAIDKVSAQMQSINETVVSLSEAFKHLTERSNEIGNITEVITSIAEQT
NLLALNAAIEAARAGEQGKGFAVVADEVRKLAEQSAQSAEQITRLITIIQNDTKQTMNSVISATGEVKEGLVVVHEAGGA
FQKIENSITEVVTQINDVTNLVKNLTAGTSEIETAISGVKEVAETAAGSTQTVSAATQEQLASMEEIAAASQILAQNAEE
LQHLIQKFKIKD

Sequences:

>Translated_572_residues
MNLLRNIKIRSKLFVIIIISALALSIVGIQGVGGLSKLSKGSEMIYQDQLIPNQLFARLKANNLDLDTYKFELMVTKDSD
RNETLQKNIKEKNEENNTLMEKIDQLKLMDNVSEKYESFKSEYKKLQDISSQMLSLAVKNENDKAYDVYLKEMEPQRETV
NQLIEDIQTLNADNAKTIYQRDSKEAGSIITLLIIVIAASLVLSISIGLLMTRLITKPIKDIQALFAETEQGDFTVKGTY
QSKDELGLLTASFNKMVAGVRSIIETVGETSHQVASSSQELSASADESTKASEYISTTIQELAVGSDQQVESVENSRTVI
KGMTEFAGRISSSAEKAAATADQTAKMSLEGTKAIDKVSAQMQSINETVVSLSEAFKHLTERSNEIGNITEVITSIAEQT
NLLALNAAIEAARAGEQGKGFAVVADEVRKLAEQSAQSAEQITRLITIIQNDTKQTMNSVISATGEVKEGLVVVHEAGGA
FQKIENSITEVVTQINDVTNLVKNLTAGTSEIETAISGVKEVAETAAGSTQTVSAATQEQLASMEEIAAASQILAQNAEE
LQHLIQKFKIKD
>Mature_572_residues
MNLLRNIKIRSKLFVIIIISALALSIVGIQGVGGLSKLSKGSEMIYQDQLIPNQLFARLKANNLDLDTYKFELMVTKDSD
RNETLQKNIKEKNEENNTLMEKIDQLKLMDNVSEKYESFKSEYKKLQDISSQMLSLAVKNENDKAYDVYLKEMEPQRETV
NQLIEDIQTLNADNAKTIYQRDSKEAGSIITLLIIVIAASLVLSISIGLLMTRLITKPIKDIQALFAETEQGDFTVKGTY
QSKDELGLLTASFNKMVAGVRSIIETVGETSHQVASSSQELSASADESTKASEYISTTIQELAVGSDQQVESVENSRTVI
KGMTEFAGRISSSAEKAAATADQTAKMSLEGTKAIDKVSAQMQSINETVVSLSEAFKHLTERSNEIGNITEVITSIAEQT
NLLALNAAIEAARAGEQGKGFAVVADEVRKLAEQSAQSAEQITRLITIIQNDTKQTMNSVISATGEVKEGLVVVHEAGGA
FQKIENSITEVVTQINDVTNLVKNLTAGTSEIETAISGVKEVAETAAGSTQTVSAATQEQLASMEEIAAASQILAQNAEE
LQHLIQKFKIKD

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=344, Percent_Identity=31.1046511627907, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788194, Length=429, Percent_Identity=27.972027972028, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=28.2051282051282, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787690, Length=431, Percent_Identity=25.754060324826, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI2367378, Length=369, Percent_Identity=28.1842818428184, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62261; Mature: 62261

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLRNIKIRSKLFVIIIISALALSIVGIQGVGGLSKLSKGSEMIYQDQLIPNQLFARLK
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCHHHHHHHHH
ANNLDLDTYKFELMVTKDSDRNETLQKNIKEKNEENNTLMEKIDQLKLMDNVSEKYESFK
CCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SEYKKLQDISSQMLSLAVKNENDKAYDVYLKEMEPQRETVNQLIEDIQTLNADNAKTIYQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHH
RDSKEAGSIITLLIIVIAASLVLSISIGLLMTRLITKPIKDIQALFAETEQGDFTVKGTY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
QSKDELGLLTASFNKMVAGVRSIIETVGETSHQVASSSQELSASADESTKASEYISTTIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHH
ELAVGSDQQVESVENSRTVIKGMTEFAGRISSSAEKAAATADQTAKMSLEGTKAIDKVSA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QMQSINETVVSLSEAFKHLTERSNEIGNITEVITSIAEQTNLLALNAAIEAARAGEQGKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FAVVADEVRKLAEQSAQSAEQITRLITIIQNDTKQTMNSVISATGEVKEGLVVVHEAGGA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
FQKIENSITEVVTQINDVTNLVKNLTAGTSEIETAISGVKEVAETAAGSTQTVSAATQEQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LASMEEIAAASQILAQNAEELQHLIQKFKIKD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLLRNIKIRSKLFVIIIISALALSIVGIQGVGGLSKLSKGSEMIYQDQLIPNQLFARLK
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCHHHHHHHHH
ANNLDLDTYKFELMVTKDSDRNETLQKNIKEKNEENNTLMEKIDQLKLMDNVSEKYESFK
CCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SEYKKLQDISSQMLSLAVKNENDKAYDVYLKEMEPQRETVNQLIEDIQTLNADNAKTIYQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHH
RDSKEAGSIITLLIIVIAASLVLSISIGLLMTRLITKPIKDIQALFAETEQGDFTVKGTY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
QSKDELGLLTASFNKMVAGVRSIIETVGETSHQVASSSQELSASADESTKASEYISTTIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHH
ELAVGSDQQVESVENSRTVIKGMTEFAGRISSSAEKAAATADQTAKMSLEGTKAIDKVSA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QMQSINETVVSLSEAFKHLTERSNEIGNITEVITSIAEQTNLLALNAAIEAARAGEQGKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FAVVADEVRKLAEQSAQSAEQITRLITIIQNDTKQTMNSVISATGEVKEGLVVVHEAGGA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
FQKIENSITEVVTQINDVTNLVKNLTAGTSEIETAISGVKEVAETAAGSTQTVSAATQEQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LASMEEIAAASQILAQNAEELQHLIQKFKIKD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA