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The map label for this gene is mpr

Identifier: 52784162

GI number: 52784162

Start: 316631

End: 317581

Strand: Reverse

Name: mpr

Synonym: BLi00340

Alternate gene names: 52784162

Gene position: 317581-316631 (Counterclockwise)

Preceding gene: 52784166

Following gene: 52784157

Centisome position: 7.52

GC content: 48.37

Gene sequence:

>951_bases
TTGGTTAGTAAAAAGAGTGTTAAACGAGGTTTGATCACAGGTCTCATTGGTATTTCTATTTATTCTTTAGGTATGCACCC
GGCCCAAGCCGCGCCATCGCCTCATACTCCTGTTTCAAGCGATCCTTCATACAAAGCGGAAACATCGGTTACTTATGACC
CAAACATTAAGAGCGATCAATACGGCTTGTATTCAAAAGCGTTTACAGGCACCGGCAAAGTGAATGAAACAAAGGAAAAA
GCGGAAAAAAAGTCACCCGCCAAAGCTCCTTACAGCATTAAATCGGTGATTGGTTCTGATGATCGGACAAGGGTCACCAA
CACAACCGCATATCCGTACAGAGCGATCGTTCATATTTCAAGCAGCATCGGTTCATGCACCGGATGGATGATCGGTCCGA
AAACCGTCGCAACAGCCGGACACTGCATCTATGACACATCAAGCGGTTCATTTGCCGGTACAGCCACTGTTTCGCCGGGA
CGGAACGGGACAAGCTATCCTTACGGCTCAGTTAAATCGACGCGCTACTTTATTCCGTCAGGATGGAGAAGCGGAAACAC
CAATTACGATTACGGCGCAATCGAACTAAGCGAACCGATCGGCAATACTGTCGGATACTTCGGATACTCGTACACTACTT
CATCACTTGTTGGGACAACTGTTACCATCAGCGGCTACCCAGGCGATAAAACAGCAGGCACACAATGGCAGCATTCAGGA
CCGATTGCCATCTCCGAAACGTATAAATTGCAGTACGCAATGGACACGTACGGAGGACAAAGCGGTTCACCGGTATTCGA
ACAAAGCAGCTCCAGAACGAACTGCAGCGGTCCGTGCTCGCTTGCCGTACACACAAATGGAGTATACGGCGGCTCCTCGT
ACAACAGAGGCACCCGGATTACAAAAGAGGTGTTCGACAATTTGACCAACTGGAAAAACAGCGCACAATAA

Upstream 100 bases:

>100_bases
ACACACCTTTAGTATGATCTTTTTTAAACATATGGAAAATTCAGAATTATTTTGTTAATATCTAACTTGTACTTACAACA
AAATAAGGAAGTGATATGAT

Downstream 100 bases:

>100_bases
TACACGAAGACAGCCCGCTTCCTTTTGGAACGGGCTGTCACATCTAACGGCCGTATACTTAATTTCCTTTAAGCCTGTAC
TTTTTGCCATCTATTGATAT

Product: Mpr

Products: NA

Alternate protein names: Glutamate-specific endopeptidase; GSE

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MVSKKSVKRGLITGLIGISIYSLGMHPAQAAPSPHTPVSSDPSYKAETSVTYDPNIKSDQYGLYSKAFTGTGKVNETKEK
AEKKSPAKAPYSIKSVIGSDDRTRVTNTTAYPYRAIVHISSSIGSCTGWMIGPKTVATAGHCIYDTSSGSFAGTATVSPG
RNGTSYPYGSVKSTRYFIPSGWRSGNTNYDYGAIELSEPIGNTVGYFGYSYTTSSLVGTTVTISGYPGDKTAGTQWQHSG
PIAISETYKLQYAMDTYGGQSGSPVFEQSSSRTNCSGPCSLAVHTNGVYGGSSYNRGTRITKEVFDNLTNWKNSAQ

Sequences:

>Translated_316_residues
MVSKKSVKRGLITGLIGISIYSLGMHPAQAAPSPHTPVSSDPSYKAETSVTYDPNIKSDQYGLYSKAFTGTGKVNETKEK
AEKKSPAKAPYSIKSVIGSDDRTRVTNTTAYPYRAIVHISSSIGSCTGWMIGPKTVATAGHCIYDTSSGSFAGTATVSPG
RNGTSYPYGSVKSTRYFIPSGWRSGNTNYDYGAIELSEPIGNTVGYFGYSYTTSSLVGTTVTISGYPGDKTAGTQWQHSG
PIAISETYKLQYAMDTYGGQSGSPVFEQSSSRTNCSGPCSLAVHTNGVYGGSSYNRGTRITKEVFDNLTNWKNSAQ
>Mature_316_residues
MVSKKSVKRGLITGLIGISIYSLGMHPAQAAPSPHTPVSSDPSYKAETSVTYDPNIKSDQYGLYSKAFTGTGKVNETKEK
AEKKSPAKAPYSIKSVIGSDDRTRVTNTTAYPYRAIVHISSSIGSCTGWMIGPKTVATAGHCIYDTSSGSFAGTATVSPG
RNGTSYPYGSVKSTRYFIPSGWRSGNTNYDYGAIELSEPIGNTVGYFGYSYTTSSLVGTTVTISGYPGDKTAGTQWQHSG
PIAISETYKLQYAMDTYGGQSGSPVFEQSSSRTNCSGPCSLAVHTNGVYGGSSYNRGTRITKEVFDNLTNWKNSAQ

Specific function: Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues, with a strong preference for Glu

COG id: COG3591

COG function: function code E; V8-like Glu-specific endopeptidase

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GSEP_BACLD (P80057)

Other databases:

- EMBL:   D10060
- EMBL:   AE017333
- EMBL:   CP000002
- PIR:   A45134
- RefSeq:   YP_077583.1
- RefSeq:   YP_089991.1
- ProteinModelPortal:   P80057
- SMR:   P80057
- STRING:   P80057
- MEROPS:   S01.271
- EnsemblBacteria:   EBBACT00000054751
- EnsemblBacteria:   EBBACT00000061174
- GeneID:   3028461
- GeneID:   3101563
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00340
- KEGG:   bli:BL01804
- NMPDR:   fig|279010.5.peg.2193
- eggNOG:   COG3591
- GeneTree:   EBGT00050000002540
- HOGENOM:   HBG502435
- OMA:   PYRAIVH
- ProtClustDB:   CLSK737620
- BioCyc:   BLIC279010-1:BLI00340-MONOMER
- BioCyc:   BLIC279010:BL01804-MONOMER
- GO:   GO:0006508
- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256
- PRINTS:   PR00839
- SMART:   SM00020

Pfam domain/function: PF00089 Trypsin; SSF50494 Pept_Ser_Cys

EC number: =3.4.21.19

Molecular weight: Translated: 33611; Mature: 33611

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00672 V8_HIS; PS00673 V8_SER

Important sites: ACT_SITE 141-141 ACT_SITE 261-261

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKKSVKRGLITGLIGISIYSLGMHPAQAAPSPHTPVSSDPSYKAETSVTYDPNIKSDQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
YGLYSKAFTGTGKVNETKEKAEKKSPAKAPYSIKSVIGSDDRTRVTNTTAYPYRAIVHIS
CCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEECCCCCCEEEEEEEE
SSIGSCTGWMIGPKTVATAGHCIYDTSSGSFAGTATVSPGRNGTSYPYGSVKSTRYFIPS
CCCCCCCCCEECCHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCC
GWRSGNTNYDYGAIELSEPIGNTVGYFGYSYTTSSLVGTTVTISGYPGDKTAGTQWQHSG
CCCCCCCCCCEEEEEECCCCCCCHHHCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCC
PIAISETYKLQYAMDTYGGQSGSPVFEQSSSRTNCSGPCSLAVHTNGVYGGSSYNRGTRI
CEEEEEEEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCEECCCCCCCCCHH
TKEVFDNLTNWKNSAQ
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVSKKSVKRGLITGLIGISIYSLGMHPAQAAPSPHTPVSSDPSYKAETSVTYDPNIKSDQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
YGLYSKAFTGTGKVNETKEKAEKKSPAKAPYSIKSVIGSDDRTRVTNTTAYPYRAIVHIS
CCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEECCCCCCEEEEEEEE
SSIGSCTGWMIGPKTVATAGHCIYDTSSGSFAGTATVSPGRNGTSYPYGSVKSTRYFIPS
CCCCCCCCCEECCHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCC
GWRSGNTNYDYGAIELSEPIGNTVGYFGYSYTTSSLVGTTVTISGYPGDKTAGTQWQHSG
CCCCCCCCCCEEEEEECCCCCCCHHHCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCC
PIAISETYKLQYAMDTYGGQSGSPVFEQSSSRTNCSGPCSLAVHTNGVYGGSSYNRGTRI
CEEEEEEEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCEECCCCCCCCCHH
TKEVFDNLTNWKNSAQ
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1429718; 1346764