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The map label for this gene is citT [H]

Identifier: 52784050

GI number: 52784050

Start: 201141

End: 201821

Strand: Reverse

Name: citT [H]

Synonym: BLi00224

Alternate gene names: 52784050

Gene position: 201821-201141 (Counterclockwise)

Preceding gene: 52784051

Following gene: 52784049

Centisome position: 4.78

GC content: 46.11

Gene sequence:

>681_bases
TTGATTGATATCGTGATCGCGGAGGATGATTTCCGTGTAGCGCAAATTCATGAAAGATTGATCGAACAGCTTGATGGATT
CAACATTATCGGTAAAGCGGCCAATGCCAAAGAAACAATGGAAATTCTCGAGGTCCGAAAGGCCGACTTGCTGCTGTTGG
ATATTTACATGCCGGATGAGATGGGCACAACATTGATTCCTGTCATTCGAAAACGGTTTCCGGAAGTGGATATCATGATC
ATCACAGCAGCAACCGAAACATGTCATTTACAGGAATCGCTCCGGGCGGGAATTGTGCACTATTTGATTAAGCCTGTGAC
TGCCGAAAAATTCAAACAGGTGCTGCTTCAATATAAGAAAAAAAGGCAAACACTGCTTTCTCAGCCACAGGTCAGCCAAT
CAATGATTGACCAAATCTTCGGAGACTTCTCCAGCGGATCCCGTCAGGCTGAGGATTTGCCGACAGGTATCAATTCGATT
ACACTGCAAAAAATCAGGGATGTTCTGCGAGACGCAGCTAAAGGAATGACAGCCGAAGAACTCGGTGAAAAAATGGGGGC
TTCACGTACAACAGCCCGCCGCTATGCCGAATATCTCGTGTCAAAAGAAGAAGCGCGCGCTGAGCTGGAATACGGAATTA
TCGGCAGACCGGAGAGAAAATACTATTTGGCGGATGAATAA

Upstream 100 bases:

>100_bases
AACTTGGCGGTTGGATTGAAGTGGCCAATCAAAAAGGCGGCGGAGCGGTATTTACCGTTTTTATACCGAAGGAGAAGCAA
ACACGAGAGGGGGAATCCAT

Downstream 100 bases:

>100_bases
ACATGAAGAACTTTGCGATTATAATGATTTGTCTATTGATCTTAATGTCGGGGGATGAAAGACAATCGTCCGCCCCGCGT
CCCCCGGGAGGGCCGGTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIDIVIAEDDFRVAQIHERLIEQLDGFNIIGKAANAKETMEILEVRKADLLLLDIYMPDEMGTTLIPVIRKRFPEVDIMI
ITAATETCHLQESLRAGIVHYLIKPVTAEKFKQVLLQYKKKRQTLLSQPQVSQSMIDQIFGDFSSGSRQAEDLPTGINSI
TLQKIRDVLRDAAKGMTAEELGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLADE

Sequences:

>Translated_226_residues
MIDIVIAEDDFRVAQIHERLIEQLDGFNIIGKAANAKETMEILEVRKADLLLLDIYMPDEMGTTLIPVIRKRFPEVDIMI
ITAATETCHLQESLRAGIVHYLIKPVTAEKFKQVLLQYKKKRQTLLSQPQVSQSMIDQIFGDFSSGSRQAEDLPTGINSI
TLQKIRDVLRDAAKGMTAEELGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLADE
>Mature_226_residues
MIDIVIAEDDFRVAQIHERLIEQLDGFNIIGKAANAKETMEILEVRKADLLLLDIYMPDEMGTTLIPVIRKRFPEVDIMI
ITAATETCHLQESLRAGIVHYLIKPVTAEKFKQVLLQYKKKRQTLLSQPQVSQSMIDQIFGDFSSGSRQAEDLPTGINSI
TLQKIRDVLRDAAKGMTAEELGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLADE

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=222, Percent_Identity=34.2342342342342, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790566, Length=225, Percent_Identity=31.5555555555556, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25678; Mature: 25678

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIVIAEDDFRVAQIHERLIEQLDGFNIIGKAANAKETMEILEVRKADLLLLDIYMPDE
CEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCEEEEEEECCCC
MGTTLIPVIRKRFPEVDIMIITAATETCHLQESLRAGIVHYLIKPVTAEKFKQVLLQYKK
CCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KRQTLLSQPQVSQSMIDQIFGDFSSGSRQAEDLPTGINSITLQKIRDVLRDAAKGMTAEE
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLADE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
>Mature Secondary Structure
MIDIVIAEDDFRVAQIHERLIEQLDGFNIIGKAANAKETMEILEVRKADLLLLDIYMPDE
CEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCEEEEEEECCCC
MGTTLIPVIRKRFPEVDIMIITAATETCHLQESLRAGIVHYLIKPVTAEKFKQVLLQYKK
CCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KRQTLLSQPQVSQSMIDQIFGDFSSGSRQAEDLPTGINSITLQKIRDVLRDAAKGMTAEE
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLADE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]