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The map label for this gene is yacO [H]

Identifier: 52783952

GI number: 52783952

Start: 114026

End: 114775

Strand: Direct

Name: yacO [H]

Synonym: BLi00114

Alternate gene names: 52783952

Gene position: 114026-114775 (Clockwise)

Preceding gene: 52783951

Following gene: 52783953

Centisome position: 2.7

GC content: 52.8

Gene sequence:

>750_bases
ATGAGTCAGCAGCATGATTACGTCATAGGAAAAAACGCGGTCATCGAAACATTAAAGTCCGGCCGGGAATTGTATAAGCT
GTGGATGGCGGAAAACACAGTGAAGGGACAGGCTCAGCAAGTCGTCGATCTCGCCGCCAAAAATGGCGTCACGATTCATT
ATGTCCCAAGAAAAAAACTCGATCAAATGGTTTCCGGACAGCATCAAGGCGTCGTCGCCCAGGTAGCGGCTTACGAGTAT
GCCGAGCTGGATGATCTTTTTCAAAAGGCCGAAGACAGAAATGAACAGCCGTTTATCCTTGTATTAGACGAAATTGAGGA
TCCGCACAACCTGGGCTCTATTATGCGCACCGCAGACGCGGTCGGGGCTCACGGCATCGTCATTCCGAAAAGGCGCGCGG
TCGGCCTTACAACGACTGTCGCCAAAGCCTCGACAGGAGCCATCGAACATATTCCGGTCGTCAAGGTGACCAATCTGTCG
CGGACCCTGGAAGAAATGAAGGGACGGGGCATTTGGGTCGTCGGTACCGATGCGTCTGGACAACAGGACTACAGGTCGCT
GGACGGAAATATGCCGCTTGCGCTTGTCATCGGCAGCGAAGGAAAAGGCATGGGAAGGCTTGTTAAAGAGAAATGTGATT
TTCTCATTCGCCTGCCGATGGCGGGAAAGGTCACATCCCTGAACGCCTCAGTTGCAGCCGGCCTGCTGATGTATGAAGTG
TACCGGAAACGAAGCCCTCTGGGAGAATAG

Upstream 100 bases:

>100_bases
AGGCGGTCATCGGGTATCTTTTTCTTGAGAACAGGGAAGATAGGCTTAATGAACTCATCAAAGCAGCGCTGGAAAAACGG
GATGGCAGGGAGGAAGTAAA

Downstream 100 bases:

>100_bases
ACGGAATGGACATCCTGTTGGTCGACGGTTATAACATGATTGGGGCTTGGCCTCAGCTGAAAGATTTAAAAGAAAACAGT
TTTGAAGAAGCAAGGGACCT

Product: YacO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSQQHDYVIGKNAVIETLKSGRELYKLWMAENTVKGQAQQVVDLAAKNGVTIHYVPRKKLDQMVSGQHQGVVAQVAAYEY
AELDDLFQKAEDRNEQPFILVLDEIEDPHNLGSIMRTADAVGAHGIVIPKRRAVGLTTTVAKASTGAIEHIPVVKVTNLS
RTLEEMKGRGIWVVGTDASGQQDYRSLDGNMPLALVIGSEGKGMGRLVKEKCDFLIRLPMAGKVTSLNASVAAGLLMYEV
YRKRSPLGE

Sequences:

>Translated_249_residues
MSQQHDYVIGKNAVIETLKSGRELYKLWMAENTVKGQAQQVVDLAAKNGVTIHYVPRKKLDQMVSGQHQGVVAQVAAYEY
AELDDLFQKAEDRNEQPFILVLDEIEDPHNLGSIMRTADAVGAHGIVIPKRRAVGLTTTVAKASTGAIEHIPVVKVTNLS
RTLEEMKGRGIWVVGTDASGQQDYRSLDGNMPLALVIGSEGKGMGRLVKEKCDFLIRLPMAGKVTSLNASVAAGLLMYEV
YRKRSPLGE
>Mature_248_residues
SQQHDYVIGKNAVIETLKSGRELYKLWMAENTVKGQAQQVVDLAAKNGVTIHYVPRKKLDQMVSGQHQGVVAQVAAYEYA
ELDDLFQKAEDRNEQPFILVLDEIEDPHNLGSIMRTADAVGAHGIVIPKRRAVGLTTTVAKASTGAIEHIPVVKVTNLSR
TLEEMKGRGIWVVGTDASGQQDYRSLDGNMPLALVIGSEGKGMGRLVKEKCDFLIRLPMAGKVTSLNASVAAGLLMYEVY
RKRSPLGE

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=227, Percent_Identity=28.6343612334802, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1790623, Length=203, Percent_Identity=44.3349753694581, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1790083, Length=159, Percent_Identity=32.0754716981132, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788935, Length=240, Percent_Identity=25.8333333333333, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=257, Percent_Identity=27.2373540856031, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324775, Length=285, Percent_Identity=26.6666666666667, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27228; Mature: 27097

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQHDYVIGKNAVIETLKSGRELYKLWMAENTVKGQAQQVVDLAAKNGVTIHYVPRKKL
CCCCCCEEECCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECHHHH
DQMVSGQHQGVVAQVAAYEYAELDDLFQKAEDRNEQPFILVLDEIEDPHNLGSIMRTADA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
VGAHGIVIPKRRAVGLTTTVAKASTGAIEHIPVVKVTNLSRTLEEMKGRGIWVVGTDASG
CCCCCEEECCCCCCCEEHHHHHCCCCCCCCCCEEEECHHHHHHHHHCCCEEEEEECCCCC
QQDYRSLDGNMPLALVIGSEGKGMGRLVKEKCDFLIRLPMAGKVTSLNASVAAGLLMYEV
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCEEECCHHHHHHHHHHHH
YRKRSPLGE
HHHCCCCCC
>Mature Secondary Structure 
SQQHDYVIGKNAVIETLKSGRELYKLWMAENTVKGQAQQVVDLAAKNGVTIHYVPRKKL
CCCCCEEECCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECHHHH
DQMVSGQHQGVVAQVAAYEYAELDDLFQKAEDRNEQPFILVLDEIEDPHNLGSIMRTADA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
VGAHGIVIPKRRAVGLTTTVAKASTGAIEHIPVVKVTNLSRTLEEMKGRGIWVVGTDASG
CCCCCEEECCCCCCCEEHHHHHCCCCCCCCCCEEEECHHHHHHHHHCCCEEEEEECCCCC
QQDYRSLDGNMPLALVIGSEGKGMGRLVKEKCDFLIRLPMAGKVTSLNASVAAGLLMYEV
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCEEECCHHHHHHHHHHHH
YRKRSPLGE
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]