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The map label for this gene is pabA [H]

Identifier: 52783932

GI number: 52783932

Start: 88922

End: 89506

Strand: Direct

Name: pabA [H]

Synonym: BLi00091

Alternate gene names: 52783932

Gene position: 88922-89506 (Clockwise)

Preceding gene: 52783931

Following gene: 52783933

Centisome position: 2.11

GC content: 50.43

Gene sequence:

>585_bases
ATGATTCTAATGATCGACAATTACGATTCGTTTACGTACAACTTGGTTCAGTATTTAGGCGAGCTTGGCGAGGAGTTGGT
CGTCAAGCGGAACGATGAGATCACCCTTCAGGAAATAGAGGACATGTCGCCTGACTTTTTGATGATTTCTCCCGGGCCTT
GCAGTCCGGATGAGGCCGGGATCAGCCTTGAAGCGATCCGCCATTTTGCCGGGAAGATACCGATTTTCGGGGTTTGCCTC
GGACACCAGTCGATCGCCCAGGTTTTCGGCGGCGATGTCGTCAGGGCAGAGCGGCTAATGCATGGGAAAACTTCCGAGAT
TTCGCACGACGGGCTGACGGTTTTTAAAGGCCTGGAACATCCGCTCACGGCCACGAGGTATCATTCTTTGATCGTCAAAC
CGGATACACTGCCCGATTGTTTTGAGACATCGGCTTGGACGGAAGAAGGGGAGATTATGGCCATCAGGCATAAAGAACTG
CCGGTTGAAGGCGTTCAGTTCCATCCAGAGTCGATTATGACCGCTTACGGAAAAGAGATGCTGAAGAATTTTATTGAGAC
TTACCGAAAGAAAGTGAACGCATGA

Upstream 100 bases:

>100_bases
CTAGGCATGAATATAAAGAGTCAATTAAAAAGGCCCTGGCGATGAAAAAGGCGCTGCAGTTGAGTGAAGAAGAGAAAAAA
GAGCAGAGGAGAGCTGAGAT

Downstream 100 bases:

>100_bases
TCATTTACCTGAACGGTCAATATGTAAAGGAGGAGGAAGCAAGACTTTCTCCTTTTGACCATGGTTTTTTATACGGAGTC
GGGGTATTCGAAACGTTCCG

Product: para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MILMIDNYDSFTYNLVQYLGELGEELVVKRNDEITLQEIEDMSPDFLMISPGPCSPDEAGISLEAIRHFAGKIPIFGVCL
GHQSIAQVFGGDVVRAERLMHGKTSEISHDGLTVFKGLEHPLTATRYHSLIVKPDTLPDCFETSAWTEEGEIMAIRHKEL
PVEGVQFHPESIMTAYGKEMLKNFIETYRKKVNA

Sequences:

>Translated_194_residues
MILMIDNYDSFTYNLVQYLGELGEELVVKRNDEITLQEIEDMSPDFLMISPGPCSPDEAGISLEAIRHFAGKIPIFGVCL
GHQSIAQVFGGDVVRAERLMHGKTSEISHDGLTVFKGLEHPLTATRYHSLIVKPDTLPDCFETSAWTEEGEIMAIRHKEL
PVEGVQFHPESIMTAYGKEMLKNFIETYRKKVNA
>Mature_194_residues
MILMIDNYDSFTYNLVQYLGELGEELVVKRNDEITLQEIEDMSPDFLMISPGPCSPDEAGISLEAIRHFAGKIPIFGVCL
GHQSIAQVFGGDVVRAERLMHGKTSEISHDGLTVFKGLEHPLTATRYHSLIVKPDTLPDCFETSAWTEEGEIMAIRHKEL
PVEGVQFHPESIMTAYGKEMLKNFIETYRKKVNA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=62.7027027027027, Blast_Score=268, Evalue=2e-73,
Organism=Escherichia coli, GI1787517, Length=194, Percent_Identity=42.2680412371134, Blast_Score=156, Evalue=7e-40,
Organism=Escherichia coli, GI1788854, Length=192, Percent_Identity=31.7708333333333, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=50.8108108108108, Blast_Score=203, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=27.7511961722488, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323873, Length=187, Percent_Identity=29.9465240641711, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21815; Mature: 21815

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDNYDSFTYNLVQYLGELGEELVVKRNDEITLQEIEDMSPDFLMISPGPCSPDEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCEEHHHHHCCCCCEEEECCCCCCCCCCC
ISLEAIRHFAGKIPIFGVCLGHQSIAQVFGGDVVRAERLMHGKTSEISHDGLTVFKGLEH
CCHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHCCCC
PLTATRYHSLIVKPDTLPDCFETSAWTEEGEIMAIRHKELPVEGVQFHPESIMTAYGKEM
CCCHHHHEEEEECCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCEECHHHHHHHHHHHH
LKNFIETYRKKVNA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MILMIDNYDSFTYNLVQYLGELGEELVVKRNDEITLQEIEDMSPDFLMISPGPCSPDEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCEEHHHHHCCCCCEEEECCCCCCCCCCC
ISLEAIRHFAGKIPIFGVCLGHQSIAQVFGGDVVRAERLMHGKTSEISHDGLTVFKGLEH
CCHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHCCCC
PLTATRYHSLIVKPDTLPDCFETSAWTEEGEIMAIRHKELPVEGVQFHPESIMTAYGKEM
CCCHHHHEEEEECCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCEECHHHHHHHHHHHH
LKNFIETYRKKVNA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]