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The map label for this gene is pabC [H]

Identifier: 52783933

GI number: 52783933

Start: 89503

End: 90363

Strand: Direct

Name: pabC [H]

Synonym: BLi00092

Alternate gene names: 52783933

Gene position: 89503-90363 (Clockwise)

Preceding gene: 52783932

Following gene: 52783934

Centisome position: 2.12

GC content: 47.97

Gene sequence:

>861_bases
ATGATCATTTACCTGAACGGTCAATATGTAAAGGAGGAGGAAGCAAGACTTTCTCCTTTTGACCATGGTTTTTTATACGG
AGTCGGGGTATTCGAAACGTTCCGGCTTTATGAAGGGAAGCCCTTCCTTTTAGACTGGCATATGGACAGATTGAACAACG
CTTTGGAACAGCTGAAAATTGAGCTTGAGCTGACAAAAAGCGAAGTGCTTGTCATTCTTGACAGGCTGCTTCAGTTGAAT
CAGCCGCAGAATCTGGATGCGAGGGTCCGGCTAAATATATCCGCCGGTCCCGGCGGCCCCGGCCTTTTTCCTGATTCATA
CAAAAATCCCGGCGTCATGGTGATGATGAATCCTTTTCAGCCTGCATCCGTTCCGGCTGAAAAGGAGGGCGTCATCTTGC
AGGTCCGCCGCAATACGCCAGAGGGTCCGTTCCGCTTGAAATCGCATCACTTTTTAAATAATTTGTACGGAAAAAGGGAG
CTCGGACATGACGCGGCCAAAGAAGGGATTTTTCTTACCGAAGGCGGAGCTGTAGCTGAAGGAATTATTTCCAACGTTTT
TTGGCGGAAAGGCAGCTGTGTGTATACACCTTCTCTTGATACCGGCATATTAGGCGGTGTCACACGCCGCTACGTCATCG
AGCGCCTTGCAGATATGGGAATCGAAGTCATAGAGGGGGTATACCCCTTGGAAGAGCTTCTCTTTGCGGACGAAGCATGG
ATGACCAATTCCGTTCAGGAAATCGTTCCATTCCGGAGAATCGGCAGCACTGAATTTCCGGGAAAGGATGGAAATTTGTC
GAAACGTCTGCAAGAGGCATACACTAATGATAGGAAAGCAGCAAAAGAATATTTGAGTTAA

Upstream 100 bases:

>100_bases
CGGTTGAAGGCGTTCAGTTCCATCCAGAGTCGATTATGACCGCTTACGGAAAAGAGATGCTGAAGAATTTTATTGAGACT
TACCGAAAGAAAGTGAACGC

Downstream 100 bases:

>100_bases
AGGGTGAAGGATATGGCGCTTCAAACAGCGGTGCGTTCAAAGCAACTGATCGCAAAGCAATACACGTTGTCTTATGAAGA
TAAAACATTGATCATGGGAA

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MIIYLNGQYVKEEEARLSPFDHGFLYGVGVFETFRLYEGKPFLLDWHMDRLNNALEQLKIELELTKSEVLVILDRLLQLN
QPQNLDARVRLNISAGPGGPGLFPDSYKNPGVMVMMNPFQPASVPAEKEGVILQVRRNTPEGPFRLKSHHFLNNLYGKRE
LGHDAAKEGIFLTEGGAVAEGIISNVFWRKGSCVYTPSLDTGILGGVTRRYVIERLADMGIEVIEGVYPLEELLFADEAW
MTNSVQEIVPFRRIGSTEFPGKDGNLSKRLQEAYTNDRKAAKEYLS

Sequences:

>Translated_286_residues
MIIYLNGQYVKEEEARLSPFDHGFLYGVGVFETFRLYEGKPFLLDWHMDRLNNALEQLKIELELTKSEVLVILDRLLQLN
QPQNLDARVRLNISAGPGGPGLFPDSYKNPGVMVMMNPFQPASVPAEKEGVILQVRRNTPEGPFRLKSHHFLNNLYGKRE
LGHDAAKEGIFLTEGGAVAEGIISNVFWRKGSCVYTPSLDTGILGGVTRRYVIERLADMGIEVIEGVYPLEELLFADEAW
MTNSVQEIVPFRRIGSTEFPGKDGNLSKRLQEAYTNDRKAAKEYLS
>Mature_286_residues
MIIYLNGQYVKEEEARLSPFDHGFLYGVGVFETFRLYEGKPFLLDWHMDRLNNALEQLKIELELTKSEVLVILDRLLQLN
QPQNLDARVRLNISAGPGGPGLFPDSYKNPGVMVMMNPFQPASVPAEKEGVILQVRRNTPEGPFRLKSHHFLNNLYGKRE
LGHDAAKEGIFLTEGGAVAEGIISNVFWRKGSCVYTPSLDTGILGGVTRRYVIERLADMGIEVIEGVYPLEELLFADEAW
MTNSVQEIVPFRRIGSTEFPGKDGNLSKRLQEAYTNDRKAAKEYLS

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=283, Percent_Identity=26.8551236749117, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787338, Length=258, Percent_Identity=27.5193798449612, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 32250; Mature: 32250

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIYLNGQYVKEEEARLSPFDHGFLYGVGVFETFRLYEGKPFLLDWHMDRLNNALEQLKI
CEEEECCCEECCHHCCCCCCCCCCEEHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHEE
ELELTKSEVLVILDRLLQLNQPQNLDARVRLNISAGPGGPGLFPDSYKNPGVMVMMNPFQ
EEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCC
PASVPAEKEGVILQVRRNTPEGPFRLKSHHFLNNLYGKRELGHDAAKEGIFLTEGGAVAE
CCCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHCCEEEECCCHHHH
GIISNVFWRKGSCVYTPSLDTGILGGVTRRYVIERLADMGIEVIEGVYPLEELLFADEAW
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHH
MTNSVQEIVPFRRIGSTEFPGKDGNLSKRLQEAYTNDRKAAKEYLS
HHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MIIYLNGQYVKEEEARLSPFDHGFLYGVGVFETFRLYEGKPFLLDWHMDRLNNALEQLKI
CEEEECCCEECCHHCCCCCCCCCCEEHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHEE
ELELTKSEVLVILDRLLQLNQPQNLDARVRLNISAGPGGPGLFPDSYKNPGVMVMMNPFQ
EEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCC
PASVPAEKEGVILQVRRNTPEGPFRLKSHHFLNNLYGKRELGHDAAKEGIFLTEGGAVAE
CCCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHCCEEEECCCHHHH
GIISNVFWRKGSCVYTPSLDTGILGGVTRRYVIERLADMGIEVIEGVYPLEELLFADEAW
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHH
MTNSVQEIVPFRRIGSTEFPGKDGNLSKRLQEAYTNDRKAAKEYLS
HHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]