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The map label for this gene is pabB [H]

Identifier: 52783931

GI number: 52783931

Start: 87492

End: 88925

Strand: Direct

Name: pabB [H]

Synonym: BLi00090

Alternate gene names: 52783931

Gene position: 87492-88925 (Clockwise)

Preceding gene: 52783930

Following gene: 52783932

Centisome position: 2.07

GC content: 48.68

Gene sequence:

>1434_bases
ATGATGAGACAACGAAGGCCTGTAGCCAGAGCGTTCCCATTTTCCAATCAACAGTTTTTGCAGCAATATGAAAGCCTATC
GAAAGGAAAAGAATACCACGTTCTGCTGGAAAGCGCGAGAGGCGGAGAATACAGCATAGCCGGACTCGACCCTGTCGCAA
TAGCGAAAGGGAAAGACGGTATCACGACGATTCAATATAAAGGGGACGTCATATTCAAAGAGGGGGATCCGTTTCTGCAG
TTTTCTCAATGGTTTGAAACGCTGAAAACGGAGACAGTTGCAGATTTTCCCGACTTTCAGGGCGGGGCTGTCGGTTTTCT
TAGCTATGACTATGCCCGGTATATTGAGAAATTCAAAATCCTGTCTATTGATGATCTGCAAACGCCGGATTTATTCTTTC
TCGTATTTGATGATATAGCCGTCTATGACCATGAGCAGCAGCAGCTTTGGGTGATTACCCACACTGATGAAGAAACGCCG
GCCGCTGCGGAAGAGAAATTGGACAGGCTTGAGCAAATGTGGAAGACGGAACATCCGAAGGCCGCTGGAGGTCATCAGCC
GAATGATAACAAAGGCCCGGCATTCGCGGCCTCATTTACAGAAGCCGGCTTTTCTCAGGCTGTTGAGAAAGTGAAGCAAT
ACATCGCAAGCGGTGACGTATTTCAGGTGAATCTTTCTGTTCGCCAGTCGGAGCGCCTTTCTGCGCCTCCTTATGAGGTG
TATAAGATGTTAAGAGAAATCAACCCTTCGCCGTACATGGCCTACTTGGAAACCCCGGATTTTCAAATCATCTGCGGGTC
GCCTGAACTGCTCATTAAGAAAAAGGGCACCAGGCTTGAAACAAGGCCGATTGCCGGAACGCGATCCCGCGGGGCGGATG
AAGCGGAGGATGAAGCGCTCGCGAACGAATTGATCATGAATGAAAAAGAGCGCGCCGAACATGTGATGCTCGTTGATTTA
GAGCGTAATGACCTCGGCAGGGTCTCCAAGTACGGTTCGGTCCGGGTCGATGAATTCATGGTGATTGAGAAGTATTCCCA
CGTCATGCATATTGTCTCAAATGTGTGCGGTGAACTAAGGGATGAATGCGATGCCGTTGATGTCATCCATGCCGTGTTTC
CCGGAGGTACGATCACCGGAGCGCCGAAAGTCAGAACGATGGAAATTATTGAGGAGCTTGAGCCAACGAGACGGGGGCTT
TATACTGGTTCTATAGGGTGGTTCGGATATAATCAGGATATGCACTTTAATATCGTCATCCGAACGATTTATGTGAAAGC
GGGCCAGGCGTTCATGCAGTCGGGAGCGGGAATCGTCATCGATTCAAATCCTAGGCATGAATATAAAGAGTCAATTAAAA
AGGCCCTGGCGATGAAAAAGGCGCTGCAGTTGAGTGAAGAAGAGAAAAAAGAGCAGAGGAGAGCTGAGATATGA

Upstream 100 bases:

>100_bases
TGCTCAAGGGCTTTTTTCTGTATTGGAAATGAAATTCTCTTTTCCTAGAAAAAAGATATGCATTACAATAAGGACATTAG
ACTAACGGCAGAGGAATGAT

Downstream 100 bases:

>100_bases
TTCTAATGATCGACAATTACGATTCGTTTACGTACAACTTGGTTCAGTATTTAGGCGAGCTTGGCGAGGAGTTGGTCGTC
AAGCGGAACGATGAGATCAC

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMRQRRPVARAFPFSNQQFLQQYESLSKGKEYHVLLESARGGEYSIAGLDPVAIAKGKDGITTIQYKGDVIFKEGDPFLQ
FSQWFETLKTETVADFPDFQGGAVGFLSYDYARYIEKFKILSIDDLQTPDLFFLVFDDIAVYDHEQQQLWVITHTDEETP
AAAEEKLDRLEQMWKTEHPKAAGGHQPNDNKGPAFAASFTEAGFSQAVEKVKQYIASGDVFQVNLSVRQSERLSAPPYEV
YKMLREINPSPYMAYLETPDFQIICGSPELLIKKKGTRLETRPIAGTRSRGADEAEDEALANELIMNEKERAEHVMLVDL
ERNDLGRVSKYGSVRVDEFMVIEKYSHVMHIVSNVCGELRDECDAVDVIHAVFPGGTITGAPKVRTMEIIEELEPTRRGL
YTGSIGWFGYNQDMHFNIVIRTIYVKAGQAFMQSGAGIVIDSNPRHEYKESIKKALAMKKALQLSEEEKKEQRRAEI

Sequences:

>Translated_477_residues
MMRQRRPVARAFPFSNQQFLQQYESLSKGKEYHVLLESARGGEYSIAGLDPVAIAKGKDGITTIQYKGDVIFKEGDPFLQ
FSQWFETLKTETVADFPDFQGGAVGFLSYDYARYIEKFKILSIDDLQTPDLFFLVFDDIAVYDHEQQQLWVITHTDEETP
AAAEEKLDRLEQMWKTEHPKAAGGHQPNDNKGPAFAASFTEAGFSQAVEKVKQYIASGDVFQVNLSVRQSERLSAPPYEV
YKMLREINPSPYMAYLETPDFQIICGSPELLIKKKGTRLETRPIAGTRSRGADEAEDEALANELIMNEKERAEHVMLVDL
ERNDLGRVSKYGSVRVDEFMVIEKYSHVMHIVSNVCGELRDECDAVDVIHAVFPGGTITGAPKVRTMEIIEELEPTRRGL
YTGSIGWFGYNQDMHFNIVIRTIYVKAGQAFMQSGAGIVIDSNPRHEYKESIKKALAMKKALQLSEEEKKEQRRAEI
>Mature_477_residues
MMRQRRPVARAFPFSNQQFLQQYESLSKGKEYHVLLESARGGEYSIAGLDPVAIAKGKDGITTIQYKGDVIFKEGDPFLQ
FSQWFETLKTETVADFPDFQGGAVGFLSYDYARYIEKFKILSIDDLQTPDLFFLVFDDIAVYDHEQQQLWVITHTDEETP
AAAEEKLDRLEQMWKTEHPKAAGGHQPNDNKGPAFAASFTEAGFSQAVEKVKQYIASGDVFQVNLSVRQSERLSAPPYEV
YKMLREINPSPYMAYLETPDFQIICGSPELLIKKKGTRLETRPIAGTRSRGADEAEDEALANELIMNEKERAEHVMLVDL
ERNDLGRVSKYGSVRVDEFMVIEKYSHVMHIVSNVCGELRDECDAVDVIHAVFPGGTITGAPKVRTMEIIEELEPTRRGL
YTGSIGWFGYNQDMHFNIVIRTIYVKAGQAFMQSGAGIVIDSNPRHEYKESIKKALAMKKALQLSEEEKKEQRRAEI

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=369, Percent_Identity=36.5853658536585, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1787518, Length=370, Percent_Identity=36.4864864864865, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786809, Length=218, Percent_Identity=27.9816513761468, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082077, Length=268, Percent_Identity=24.6268656716418, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320935, Length=450, Percent_Identity=38, Blast_Score=277, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6324361, Length=369, Percent_Identity=26.5582655826558, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 54085; Mature: 54085

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRQRRPVARAFPFSNQQFLQQYESLSKGKEYHVLLESARGGEYSIAGLDPVAIAKGKDG
CCCCCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCEEEECCCCC
ITTIQYKGDVIFKEGDPFLQFSQWFETLKTETVADFPDFQGGAVGFLSYDYARYIEKFKI
CEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHEE
LSIDDLQTPDLFFLVFDDIAVYDHEQQQLWVITHTDEETPAAAEEKLDRLEQMWKTEHPK
EEECCCCCCCEEEEEEECEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
AAGGHQPNDNKGPAFAASFTEAGFSQAVEKVKQYIASGDVFQVNLSVRQSERLSAPPYEV
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHH
YKMLREINPSPYMAYLETPDFQIICGSPELLIKKKGTRLETRPIAGTRSRGADEAEDEAL
HHHHHHCCCCCEEEEEECCCEEEEECCCCEEEECCCCEEECCCCCCCCCCCCCCHHHHHH
ANELIMNEKERAEHVMLVDLERNDLGRVSKYGSVRVDEFMVIEKYSHVMHIVSNVCGELR
HHHHHHCCHHHCCEEEEEEECCCCCCCHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
DECDAVDVIHAVFPGGTITGAPKVRTMEIIEELEPTRRGLYTGSIGWFGYNQDMHFNIVI
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHCCCEECCEEEEECCCCEEEEEEE
RTIYVKAGQAFMQSGAGIVIDSNPRHEYKESIKKALAMKKALQLSEEEKKEQRRAEI
EEEEEHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRQRRPVARAFPFSNQQFLQQYESLSKGKEYHVLLESARGGEYSIAGLDPVAIAKGKDG
CCCCCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCEEEECCCCC
ITTIQYKGDVIFKEGDPFLQFSQWFETLKTETVADFPDFQGGAVGFLSYDYARYIEKFKI
CEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHEE
LSIDDLQTPDLFFLVFDDIAVYDHEQQQLWVITHTDEETPAAAEEKLDRLEQMWKTEHPK
EEECCCCCCCEEEEEEECEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
AAGGHQPNDNKGPAFAASFTEAGFSQAVEKVKQYIASGDVFQVNLSVRQSERLSAPPYEV
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHH
YKMLREINPSPYMAYLETPDFQIICGSPELLIKKKGTRLETRPIAGTRSRGADEAEDEAL
HHHHHHCCCCCEEEEEECCCEEEEECCCCEEEECCCCEEECCCCCCCCCCCCCCHHHHHH
ANELIMNEKERAEHVMLVDLERNDLGRVSKYGSVRVDEFMVIEKYSHVMHIVSNVCGELR
HHHHHHCCHHHCCEEEEEEECCCCCCCHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
DECDAVDVIHAVFPGGTITGAPKVRTMEIIEELEPTRRGLYTGSIGWFGYNQDMHFNIVI
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHCCCEECCEEEEECCCCEEEEEEE
RTIYVKAGQAFMQSGAGIVIDSNPRHEYKESIKKALAMKKALQLSEEEKKEQRRAEI
EEEEEHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]