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The map label for this gene is dnaX [H]

Identifier: 52783877

GI number: 52783877

Start: 30881

End: 32581

Strand: Direct

Name: dnaX [H]

Synonym: BLi00028

Alternate gene names: 52783877

Gene position: 30881-32581 (Clockwise)

Preceding gene: 52783876

Following gene: 52783878

Centisome position: 0.73

GC content: 47.03

Gene sequence:

>1701_bases
GTGAGTTACCAGGCTTTATATAGAGTGTTCAGGCCGCAGTTGTTTGAAGATGTAGTCGGTCAGGAGCACATCACGAAAAC
GTTGCAAAATGCCCTTTTACAAAAGAAATTTTCGCACGCTTATCTGTTTTCCGGACCGAGGGGAACGGGAAAAACAAGCG
CCGCAAAACTGTTTGCCAAAGCTGTCAACTGTGAGCGCGCTCCGGTCAGTGAACCGTGTAACGAATGCTCCGCGTGCAAA
GGCATTACAAACGGTTCGATTTCAGATGTGATCGAAATTGACGCCGCTTCTAACAACGGTGTAGATGAAATACGCGACAT
CCGCGACAAGGTGAAATTTGCCCCGTCTGCCGTCACGTATAAAGTATATATCATAGATGAAGTACATATGCTTTCTATCG
GCGCATTCAACGCCCTTCTAAAAACGCTTGAAGAGCCGCCGGAGCATTGTATCTTTATTCTCGCAACAACAGAGCCTCAT
AAAATTCCTTTAACGATTATTTCTAGATGTCAGCGATTTGATTTTAAGAGGATTACCTCGCAGGCAATTGTCGGACGAAT
GAAAAAAATCGTCGAAGCTGAACAGTTAAAGGTGCAGGACGGAGCCTTAGACATCATCGCCAGTGCCGCGGACGGCGGCA
TGAGGGATGCGCTGAGCCTGCTCGATCAGGCCGTATCATTCAGCGGAGAAGAGCTGACGGTGGATGATGCGCTGCTGATA
ACAGGCGCCGTGTCACAGCACTATATTGGAAAGCTCGCCTCAACCCTTCACGAAAAAAATGTTTCCGGTGCTTTGGAAAC
ATTGAACGAACTCCTTCAGCAGGGGAAAGATCCGGCAAAATTAATCGAGGATATGATTTTCTACTTCAGGGATATGCTTC
TTTATCAAACGGCGCCCGATTTAGAAGGCGTTCTTGAAAAGGTGAAGGTGGACGAAGAGTTCCAAACCCTATCCCGGCAA
ATTCCCGCATCAGACCTTTACGAAATGATCGATATATTAAATAAAAGCCATCAGGAAATGAAATGGACGAATCATCCGCG
TATCTTCTTTGAAGTTGCGGTTGTGAAGCTCTGCCAGGGACCAAAAGCAGGGGCATCCGCGGCCGCCCAGCCGGAAGTGG
ACAATCTCGTCAACAAGGTTCGGCAGCTTGAACAGGAGATTGAGAGGCTTAAAACACAAGGTGTGCAGGTCTCTTCTGCT
CCCGCCCAGGCTAAAGAAGCGTCCCGTCCGCAAAAAAGCATAAAAAGCGCGTATAAAGCGCCTGTCGGCCGCATTCATGA
AATATTAAAGGATGCCACAAGACCGGATCTCGAAAAATTAAAGGGCTGCTGGGGACAATTGCTTGCCCAGCTGAAACAGC
AGAATAAAGTATCACATGCGGCCCTTTTAAATGACAGCGAACCGGTGGCTGCATCTTCAAAAGCATTTGTCCTCGCATTC
AAATACGAAATTCACTGTAAAATGGTAGCTGAAGACAACAACGGAGTCAGGACGAATCTGGAACAAATTTTGGACGGAAT
GCTCGGCGGAAGGATAGATATAGTTGGCGTTCCCGAAGCCCAATGGGGTAAAATAAGAGAAGAATTTTTGCAGGATCACC
AGCCGGAAGATTCTGAAGCAAACGAACCGAAAGAAGAAGATCCGCTCGTAGCAGAAGCTAAAAAACTGTTCGGAGCGGAA
CTGATTGAAATTAAAGAATAA

Upstream 100 bases:

>100_bases
TATTTGAATATAGATGAGTTTTTTTCTTAAGAAGAGCTTTTGGATTTGAAAGCCGCATCATGTATAATGGAAATGATGAA
AACAAGAGGAGGGCGTGTTT

Downstream 100 bases:

>100_bases
AAACATGAAAGAGAGTGGATTTGAGTATGCGCGGTGGAATGGGTAACATGCAGAAAATGATGAAGCAAATGCAAAAAATG
CAAAAGGATATGCAAAAGGC

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MSYQALYRVFRPQLFEDVVGQEHITKTLQNALLQKKFSHAYLFSGPRGTGKTSAAKLFAKAVNCERAPVSEPCNECSACK
GITNGSISDVIEIDAASNNGVDEIRDIRDKVKFAPSAVTYKVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPH
KIPLTIISRCQRFDFKRITSQAIVGRMKKIVEAEQLKVQDGALDIIASAADGGMRDALSLLDQAVSFSGEELTVDDALLI
TGAVSQHYIGKLASTLHEKNVSGALETLNELLQQGKDPAKLIEDMIFYFRDMLLYQTAPDLEGVLEKVKVDEEFQTLSRQ
IPASDLYEMIDILNKSHQEMKWTNHPRIFFEVAVVKLCQGPKAGASAAAQPEVDNLVNKVRQLEQEIERLKTQGVQVSSA
PAQAKEASRPQKSIKSAYKAPVGRIHEILKDATRPDLEKLKGCWGQLLAQLKQQNKVSHAALLNDSEPVAASSKAFVLAF
KYEIHCKMVAEDNNGVRTNLEQILDGMLGGRIDIVGVPEAQWGKIREEFLQDHQPEDSEANEPKEEDPLVAEAKKLFGAE
LIEIKE

Sequences:

>Translated_566_residues
MSYQALYRVFRPQLFEDVVGQEHITKTLQNALLQKKFSHAYLFSGPRGTGKTSAAKLFAKAVNCERAPVSEPCNECSACK
GITNGSISDVIEIDAASNNGVDEIRDIRDKVKFAPSAVTYKVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPH
KIPLTIISRCQRFDFKRITSQAIVGRMKKIVEAEQLKVQDGALDIIASAADGGMRDALSLLDQAVSFSGEELTVDDALLI
TGAVSQHYIGKLASTLHEKNVSGALETLNELLQQGKDPAKLIEDMIFYFRDMLLYQTAPDLEGVLEKVKVDEEFQTLSRQ
IPASDLYEMIDILNKSHQEMKWTNHPRIFFEVAVVKLCQGPKAGASAAAQPEVDNLVNKVRQLEQEIERLKTQGVQVSSA
PAQAKEASRPQKSIKSAYKAPVGRIHEILKDATRPDLEKLKGCWGQLLAQLKQQNKVSHAALLNDSEPVAASSKAFVLAF
KYEIHCKMVAEDNNGVRTNLEQILDGMLGGRIDIVGVPEAQWGKIREEFLQDHQPEDSEANEPKEEDPLVAEAKKLFGAE
LIEIKE
>Mature_565_residues
SYQALYRVFRPQLFEDVVGQEHITKTLQNALLQKKFSHAYLFSGPRGTGKTSAAKLFAKAVNCERAPVSEPCNECSACKG
ITNGSISDVIEIDAASNNGVDEIRDIRDKVKFAPSAVTYKVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPHK
IPLTIISRCQRFDFKRITSQAIVGRMKKIVEAEQLKVQDGALDIIASAADGGMRDALSLLDQAVSFSGEELTVDDALLIT
GAVSQHYIGKLASTLHEKNVSGALETLNELLQQGKDPAKLIEDMIFYFRDMLLYQTAPDLEGVLEKVKVDEEFQTLSRQI
PASDLYEMIDILNKSHQEMKWTNHPRIFFEVAVVKLCQGPKAGASAAAQPEVDNLVNKVRQLEQEIERLKTQGVQVSSAP
AQAKEASRPQKSIKSAYKAPVGRIHEILKDATRPDLEKLKGCWGQLLAQLKQQNKVSHAALLNDSEPVAASSKAFVLAFK
YEIHCKMVAEDNNGVRTNLEQILDGMLGGRIDIVGVPEAQWGKIREEFLQDHQPEDSEANEPKEEDPLVAEAKKLFGAEL
IEIKE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=266, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194306571, Length=266, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI194306567, Length=266, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI31563534, Length=307, Percent_Identity=25.4071661237785, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4506491, Length=294, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI31881687, Length=294, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI194306569, Length=186, Percent_Identity=26.3440860215054, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786676, Length=356, Percent_Identity=39.3258426966292, Blast_Score=270, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71986063, Length=305, Percent_Identity=25.2459016393443, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17541988, Length=223, Percent_Identity=28.2511210762332, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554730, Length=227, Percent_Identity=26.431718061674, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324039, Length=217, Percent_Identity=28.110599078341, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322528, Length=300, Percent_Identity=24.3333333333333, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324478, Length=225, Percent_Identity=24.8888888888889, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859927, Length=299, Percent_Identity=23.7458193979933, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921076, Length=237, Percent_Identity=26.5822784810127, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17647857, Length=282, Percent_Identity=23.0496453900709, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 62716; Mature: 62585

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQALYRVFRPQLFEDVVGQEHITKTLQNALLQKKFSHAYLFSGPRGTGKTSAAKLFAK
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHH
AVNCERAPVSEPCNECSACKGITNGSISDVIEIDAASNNGVDEIRDIRDKVKFAPSAVTY
HHCCCCCCCCCHHHHHHHHCCCCCCCCHHEEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPHKIPLTIISRCQRFDFKRITS
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QAIVGRMKKIVEAEQLKVQDGALDIIASAADGGMRDALSLLDQAVSFSGEELTVDDALLI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCHHHH
TGAVSQHYIGKLASTLHEKNVSGALETLNELLQQGKDPAKLIEDMIFYFRDMLLYQTAPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
LEGVLEKVKVDEEFQTLSRQIPASDLYEMIDILNKSHQEMKWTNHPRIFFEVAVVKLCQG
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHCC
PKAGASAAAQPEVDNLVNKVRQLEQEIERLKTQGVQVSSAPAQAKEASRPQKSIKSAYKA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHCCHHHHHHHHHHC
PVGRIHEILKDATRPDLEKLKGCWGQLLAQLKQQNKVSHAALLNDSEPVAASSKAFVLAF
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEE
KYEIHCKMVAEDNNGVRTNLEQILDGMLGGRIDIVGVPEAQWGKIREEFLQDHQPEDSEA
EEEEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCC
NEPKEEDPLVAEAKKLFGAELIEIKE
CCCCCCCCHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
SYQALYRVFRPQLFEDVVGQEHITKTLQNALLQKKFSHAYLFSGPRGTGKTSAAKLFAK
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHH
AVNCERAPVSEPCNECSACKGITNGSISDVIEIDAASNNGVDEIRDIRDKVKFAPSAVTY
HHCCCCCCCCCHHHHHHHHCCCCCCCCHHEEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSIGAFNALLKTLEEPPEHCIFILATTEPHKIPLTIISRCQRFDFKRITS
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QAIVGRMKKIVEAEQLKVQDGALDIIASAADGGMRDALSLLDQAVSFSGEELTVDDALLI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCHHHH
TGAVSQHYIGKLASTLHEKNVSGALETLNELLQQGKDPAKLIEDMIFYFRDMLLYQTAPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
LEGVLEKVKVDEEFQTLSRQIPASDLYEMIDILNKSHQEMKWTNHPRIFFEVAVVKLCQG
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHCC
PKAGASAAAQPEVDNLVNKVRQLEQEIERLKTQGVQVSSAPAQAKEASRPQKSIKSAYKA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHCCHHHHHHHHHHC
PVGRIHEILKDATRPDLEKLKGCWGQLLAQLKQQNKVSHAALLNDSEPVAASSKAFVLAF
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEE
KYEIHCKMVAEDNNGVRTNLEQILDGMLGGRIDIVGVPEAQWGKIREEFLQDHQPEDSEA
EEEEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCC
NEPKEEDPLVAEAKKLFGAELIEIKE
CCCCCCCCHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]