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The map label for this gene is yycG [H]

Identifier: 52145273

GI number: 52145273

Start: 5277460

End: 5279301

Strand: Reverse

Name: yycG [H]

Synonym: BCZK5162

Alternate gene names: 52145273

Gene position: 5279301-5277460 (Counterclockwise)

Preceding gene: 52145274

Following gene: 52145272

Centisome position: 99.59

GC content: 36.05

Gene sequence:

>1842_bases
ATGAAGAAAGTCGGTTTTTTTCAATCTATTCATTTAAAATTTGTACTCATATATATGCTATTAATATTGATAGCTATGCA
AGTTATTGGGGTATATTTCGTAAGAGAGTTAGAAAAGAGTCTCGTACAAGGCTTTAGAGATTCATTAACGCAACAAACGA
ACTTATTATCGTATAACTTGAAACAAGAGTTTAAAAAAAGTCATACAAAAGCAGAAACAGAATCAACAGATGAAACGATT
AAAACTTCCATTCGAAAATTTGCCTCTGATCGTAAGAAAGATATTCAAGAGGTAAGTGTATTTGATTCGAATAGAAAGCT
GCTCGCTATTTCAGATGAGTCAAAGCAAAACAAGGTAAATAGAACATCAACTGATATAGCTGTTCAGCGGGTATTGGTAC
AAAAAAAACCAGAAGTGAAAATTGAGAAGGATGGTCGTACAGGTCACCGTGTACAAGTTATGATTACTCCTATTATGGAT
GATAACAACAAAGATGCACTGGGTGCTATTTACGTTGTTGCATCTATGGAAGATGTTTATAAGCAGATGAAGGATATTAA
TCAAATCTTTGCGACCGGAACCGTTATTGCATTACTCGTAACAGCTGTACTTGGAATTTTGTTAGCTCAAACGATTACGA
GGCCAATCTCTGATATGCGAAGACAAGCGATTGAAATGGCAAAAGGAAACTATTCAAGAAAAGTAAAAGTGCATAGCCAT
GATGAAATTGGACAATTAGCATTATCCTTCAATAATTTATCAAAAAAATTACAACAAGCTCGTTCTTCAACGGAAAGTGA
AAGACGTAAATTGTCATCTGTATTATCACATATGACAGATGGAGTAATTGCTACTGACCGAAAAGGGGACATTATTTTAT
TAAATGATCCTGCGGAAAAGATGCTAAATGTTTCGCGTGAAACGGCGCTTGATCAATCTGTTTTAGAAGTATTGGGAATA
CAAGAAGAATTTACGCTTGATCATTTATACGAAGAACCTGATTCTGTTTTATTAGATTTTAGTACGAGAAATGAGCCATA
TATTTTACGCGCTAGTTTCTCTGTTATTCAAAAAGAGACAGGGAAAGCAAATGGTTTAATTGCCGTATTATATGATGTAA
CTGAGCAGGAGCGTATAGAAAGGGAACGCCGCGAGTTTGTAGCAAACGTCTCTCATGAATTAAGAACGCCGTTAACGACA
ATGCGCAGTTATTTAGAGGCACTTACAGACGGTGCGTGGCAAGATCCGAATATTGCACCGCAATTTTTAACAGTTACACA
AGAAGAAACAGAAAGAATGATTAGACTTGTAAATGCGTTATTGCAACTATCTAAACTCGATAGTACAGAACATCGTTTAA
TGAAAGAATGGGTCGACTTTACTGACTTCTTTAATAACATTATTGATCGTTTCGAAATGTCTAAAGAGCAAAACGTAAGT
TTCAAACGATCTTTCTCTAAAAAATCTCGATTTATTGATATGGATACGGATAAAATTACGCAAGTATTGTACAACATTAT
TTCGAATGCATTAAAGTATTCACCAGAAGGTGGAACAGTAACATATCGCTTACGTGATCGCGGGGAATTATTAGAGATTA
GTGTAAGTGACCAAGGAATGGGTATTCCGAAAGAAAACGTCGATAAAATCTTTGAACGTTTTTATCGCGTAGATAAAGCA
CGTTCAAGACAAATGGGTGGTACAGGACTTGGATTAGCAATTGCGAAAGAAATGATTGAGGCACATGGTGGCTCGATTTG
GGCGAAGAGTGAGGAAGGAAAAGGGACAACGATTTATTTCACATTGCCAATGGCAGCGGATGAAGAGGACGATTGGGAAT
GA

Upstream 100 bases:

>100_bases
TTTACGTGAAAAAATTGAAGATAATCCAAGTCATCCTACATTAATTGTCACTAGACGTGGAGTAGGGTATTACTTGCGTG
ACCCAGAGCAGGAATAGTAT

Downstream 100 bases:

>100_bases
GTATGGAAAATGTTAAAACGATAGTTTTAATTAATTTAGTTGTAATTAGTTTATTTCTTACTTTTAACTTATGGACGTAT
GTGCCAGATTCCACATCTAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MKKVGFFQSIHLKFVLIYMLLILIAMQVIGVYFVRELEKSLVQGFRDSLTQQTNLLSYNLKQEFKKSHTKAETESTDETI
KTSIRKFASDRKKDIQEVSVFDSNRKLLAISDESKQNKVNRTSTDIAVQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMD
DNNKDALGAIYVVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKVHSH
DEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEKMLNVSRETALDQSVLEVLGI
QEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKETGKANGLIAVLYDVTEQERIERERREFVANVSHELRTPLTT
MRSYLEALTDGAWQDPNIAPQFLTVTQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVS
FKRSFSKKSRFIDMDTDKITQVLYNIISNALKYSPEGGTVTYRLRDRGELLEISVSDQGMGIPKENVDKIFERFYRVDKA
RSRQMGGTGLGLAIAKEMIEAHGGSIWAKSEEGKGTTIYFTLPMAADEEDDWE

Sequences:

>Translated_613_residues
MKKVGFFQSIHLKFVLIYMLLILIAMQVIGVYFVRELEKSLVQGFRDSLTQQTNLLSYNLKQEFKKSHTKAETESTDETI
KTSIRKFASDRKKDIQEVSVFDSNRKLLAISDESKQNKVNRTSTDIAVQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMD
DNNKDALGAIYVVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKVHSH
DEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEKMLNVSRETALDQSVLEVLGI
QEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKETGKANGLIAVLYDVTEQERIERERREFVANVSHELRTPLTT
MRSYLEALTDGAWQDPNIAPQFLTVTQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVS
FKRSFSKKSRFIDMDTDKITQVLYNIISNALKYSPEGGTVTYRLRDRGELLEISVSDQGMGIPKENVDKIFERFYRVDKA
RSRQMGGTGLGLAIAKEMIEAHGGSIWAKSEEGKGTTIYFTLPMAADEEDDWE
>Mature_613_residues
MKKVGFFQSIHLKFVLIYMLLILIAMQVIGVYFVRELEKSLVQGFRDSLTQQTNLLSYNLKQEFKKSHTKAETESTDETI
KTSIRKFASDRKKDIQEVSVFDSNRKLLAISDESKQNKVNRTSTDIAVQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMD
DNNKDALGAIYVVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKVHSH
DEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEKMLNVSRETALDQSVLEVLGI
QEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKETGKANGLIAVLYDVTEQERIERERREFVANVSHELRTPLTT
MRSYLEALTDGAWQDPNIAPQFLTVTQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVS
FKRSFSKKSRFIDMDTDKITQVLYNIISNALKYSPEGGTVTYRLRDRGELLEISVSDQGMGIPKENVDKIFERFYRVDKA
RSRQMGGTGLGLAIAKEMIEAHGGSIWAKSEEGKGTTIYFTLPMAADEEDDWE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=371, Percent_Identity=31.266846361186, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI48994928, Length=318, Percent_Identity=30.8176100628931, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=33.1896551724138, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788549, Length=382, Percent_Identity=28.0104712041885, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=31.8965517241379, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=28.3842794759825, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=30.1310043668122, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=31.7796610169492, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=27.2373540856031, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=30.2127659574468, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=27.8260869565217, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=28.6995515695067, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=31.7796610169492, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=203, Percent_Identity=26.6009852216749, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=27.0042194092827, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790551, Length=267, Percent_Identity=26.2172284644195, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789403, Length=217, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=29.7560975609756, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787374, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=27.6785714285714, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69979; Mature: 69979

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGFFQSIHLKFVLIYMLLILIAMQVIGVYFVRELEKSLVQGFRDSLTQQTNLLSYNL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQEFKKSHTKAETESTDETIKTSIRKFASDRKKDIQEVSVFDSNRKLLAISDESKQNKVN
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCC
RTSTDIAVQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMDDNNKDALGAIYVVASMEDVY
CHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
KQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKVHSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
DEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEK
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCHHH
MLNVSRETALDQSVLEVLGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKET
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHHC
GKANGLIAVLYDVTEQERIERERREFVANVSHELRTPLTTMRSYLEALTDGAWQDPNIAP
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
QFLTVTQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVS
HHEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCH
FKRSFSKKSRFIDMDTDKITQVLYNIISNALKYSPEGGTVTYRLRDRGELLEISVSDQGM
HHHHHHHHHCEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEECCCCC
GIPKENVDKIFERFYRVDKARSRQMGGTGLGLAIAKEMIEAHGGSIWAKSEEGKGTTIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
TLPMAADEEDDWE
EECCCCCCCCCCC
>Mature Secondary Structure
MKKVGFFQSIHLKFVLIYMLLILIAMQVIGVYFVRELEKSLVQGFRDSLTQQTNLLSYNL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQEFKKSHTKAETESTDETIKTSIRKFASDRKKDIQEVSVFDSNRKLLAISDESKQNKVN
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCC
RTSTDIAVQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMDDNNKDALGAIYVVASMEDVY
CHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
KQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKVHSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
DEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDGVIATDRKGDIILLNDPAEK
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCHHH
MLNVSRETALDQSVLEVLGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILRASFSVIQKET
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHHC
GKANGLIAVLYDVTEQERIERERREFVANVSHELRTPLTTMRSYLEALTDGAWQDPNIAP
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
QFLTVTQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVS
HHEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCH
FKRSFSKKSRFIDMDTDKITQVLYNIISNALKYSPEGGTVTYRLRDRGELLEISVSDQGM
HHHHHHHHHCEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEECCCCC
GIPKENVDKIFERFYRVDKARSRQMGGTGLGLAIAKEMIEAHGGSIWAKSEEGKGTTIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
TLPMAADEEDDWE
EECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]