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The map label for this gene is adhB [C]

Identifier: 52142909

GI number: 52142909

Start: 2463740

End: 2464666

Strand: Direct

Name: adhB [C]

Synonym: BCZK2331

Alternate gene names: 52142909

Gene position: 2463740-2464666 (Clockwise)

Preceding gene: 52142910

Following gene: 52142906

Centisome position: 46.48

GC content: 31.82

Gene sequence:

>927_bases
ATGGAACAAAATAAATTAGTTTTAGAAGGACCAAAATACCTTAAGTGGCAAACGTGTAAAATAAAGTCTATACAGGATGA
TGAAATTATCGTTAAAACAATTGCAGGGGCAATAAGTATTGGTGCAGAGTTACCACAGTATAATGGATCCGATGTTACAG
ATACACATCCTTTTTATCCAAGAAAAACTGGATATGAAAGTTATGGTGAAGTGATTCAAGTTGGTAATAAAGTAACGAAT
TTAAAAATAGGCGATAAAGTAGTTTCTTTTTATGGACATGAAACGATAGGAATAGTTAAGGGGTATAAAGTAATTCGAGT
ACCTAGTTATATAAAACCTAAAGTCGCTTTATTATCTATTCTTTCGTGCGATGCCGCTAAAGGCATATTGAAACTAAACC
CGCGACAGGATGAAAAGGTACTTATAACTGGAATGGGAGTTATTGGTTTACTTGCTTGTTATTTCTTAAAATACTATGTA
GGTATTGAGCATGTGGATATTGTTGAACCTGATAGGACTAGAAGGGAATTTGCACAGAAATTTAGTGTGAAAAACACATT
TGATGCAGAAGAACAGATAGTAGAAACATATAATTATGGTTTCGAATGTTCTGCTACAAATAGCGGATTCCATACATTAC
AAAAAACACTTAAAACTAATGGACAAATATGTATACTTTCTGATGGTAATATTGAAGAATTAACATTAACCGCCGATTTT
TATCAGAAAGAATTGCAAATCATTGGTTCAAGTGATGGGTATGATTATCAAAAACATGCAGATTGGTTTTTTAGTCAAAT
AGAACAAATACCATTGTTAGAAGAGATTTTTCAACATGAAATTCATTATACTGCACTTGAACAATGTTTTGAGGCATTGA
GCAAAGGGACAATACATCCATTAAAAGTATTTGTTTCATATGAATAA

Upstream 100 bases:

>100_bases
TGGGTGCTAGTCAACGTTATAGCTTAAATTTTAGATGAATTTATTATACATTGTTTGAAATTTAGTGAGAATATATTTTT
ATAAAATGAGAGGGTCATAA

Downstream 100 bases:

>100_bases
TAGATAAACTTGCAGCTTATAATTCATCCTTAAGTGGAGAATGCTACTAACATTACCCATTAAAGGATTAGGTTATTATG
AATGTTATTTTTGAAAGCAT

Product: alcohol dehydrogenase, zinc-containing

Products: aldehyde; ketone; NADH; H+

Alternate protein names: Oxidoreductase; Alcohol Dehydrogenase; Alcohol Dehydrogenase Zinc-Containing

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MEQNKLVLEGPKYLKWQTCKIKSIQDDEIIVKTIAGAISIGAELPQYNGSDVTDTHPFYPRKTGYESYGEVIQVGNKVTN
LKIGDKVVSFYGHETIGIVKGYKVIRVPSYIKPKVALLSILSCDAAKGILKLNPRQDEKVLITGMGVIGLLACYFLKYYV
GIEHVDIVEPDRTRREFAQKFSVKNTFDAEEQIVETYNYGFECSATNSGFHTLQKTLKTNGQICILSDGNIEELTLTADF
YQKELQIIGSSDGYDYQKHADWFFSQIEQIPLLEEIFQHEIHYTALEQCFEALSKGTIHPLKVFVSYE

Sequences:

>Translated_308_residues
MEQNKLVLEGPKYLKWQTCKIKSIQDDEIIVKTIAGAISIGAELPQYNGSDVTDTHPFYPRKTGYESYGEVIQVGNKVTN
LKIGDKVVSFYGHETIGIVKGYKVIRVPSYIKPKVALLSILSCDAAKGILKLNPRQDEKVLITGMGVIGLLACYFLKYYV
GIEHVDIVEPDRTRREFAQKFSVKNTFDAEEQIVETYNYGFECSATNSGFHTLQKTLKTNGQICILSDGNIEELTLTADF
YQKELQIIGSSDGYDYQKHADWFFSQIEQIPLLEEIFQHEIHYTALEQCFEALSKGTIHPLKVFVSYE
>Mature_308_residues
MEQNKLVLEGPKYLKWQTCKIKSIQDDEIIVKTIAGAISIGAELPQYNGSDVTDTHPFYPRKTGYESYGEVIQVGNKVTN
LKIGDKVVSFYGHETIGIVKGYKVIRVPSYIKPKVALLSILSCDAAKGILKLNPRQDEKVLITGMGVIGLLACYFLKYYV
GIEHVDIVEPDRTRREFAQKFSVKNTFDAEEQIVETYNYGFECSATNSGFHTLQKTLKTNGQICILSDGNIEELTLTADF
YQKELQIIGSSDGYDYQKHADWFFSQIEQIPLLEEIFQHEIHYTALEQCFEALSKGTIHPLKVFVSYE

Specific function: Threonine catabolism; first step. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.1

Molecular weight: Translated: 34895; Mature: 34895

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNKLVLEGPKYLKWQTCKIKSIQDDEIIVKTIAGAISIGAELPQYNGSDVTDTHPFYP
CCCCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RKTGYESYGEVIQVGNKVTNLKIGDKVVSFYGHETIGIVKGYKVIRVPSYIKPKVALLSI
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHH
LSCDAAKGILKLNPRQDEKVLITGMGVIGLLACYFLKYYVGIEHVDIVEPDRTRREFAQK
HHHHHHCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
FSVKNTFDAEEQIVETYNYGFECSATNSGFHTLQKTLKTNGQICILSDGNIEELTLTADF
HCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHH
YQKELQIIGSSDGYDYQKHADWFFSQIEQIPLLEEIFQHEIHYTALEQCFEALSKGTIHP
HHHHHHEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LKVFVSYE
EEEEEECC
>Mature Secondary Structure
MEQNKLVLEGPKYLKWQTCKIKSIQDDEIIVKTIAGAISIGAELPQYNGSDVTDTHPFYP
CCCCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RKTGYESYGEVIQVGNKVTNLKIGDKVVSFYGHETIGIVKGYKVIRVPSYIKPKVALLSI
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHH
LSCDAAKGILKLNPRQDEKVLITGMGVIGLLACYFLKYYVGIEHVDIVEPDRTRREFAQK
HHHHHHCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
FSVKNTFDAEEQIVETYNYGFECSATNSGFHTLQKTLKTNGQICILSDGNIEELTLTADF
HCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHH
YQKELQIIGSSDGYDYQKHADWFFSQIEQIPLLEEIFQHEIHYTALEQCFEALSKGTIHP
HHHHHHEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LKVFVSYE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA