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The map label for this gene is fruR [H]

Identifier: 52141770

GI number: 52141770

Start: 3603411

End: 3604163

Strand: Reverse

Name: fruR [H]

Synonym: BCZK3478

Alternate gene names: 52141770

Gene position: 3604163-3603411 (Counterclockwise)

Preceding gene: 52141767

Following gene: 52141769

Centisome position: 67.99

GC content: 35.86

Gene sequence:

>753_bases
ATGTTAACTCCTGAACGTCATCAAATGATATTGCAACTTGTAAAAGAGCAGAAGGTTGTTAAATTACAGCAATTAGTGGA
AAGAACAGCGAGCTCTGAATCAACAATTCGTCGTGATTTAGCGCAATTGGAAAAACAACGGTTATTAAAAAGAGTTCACG
GTGGTGCGGCTGTTTTAACAGGAAAAGGACAGGAGCCGACGATGGTTGAAAAATCATCCAAAAACATTCAGATAAAACAA
CAAATTGCGAAGTATGCGGCTAGCGTTGTGGAACAAGGTGATTGCATTTATTTAGATGCAGGAAGTACAACATTTGAAAT
GATTCCATTTTTAATAAATAAAGATGTTACTGTCGTTACGAATGGACTTATGCATATTGAAGCTTTAGTTGAAAATAATA
TTCGGGCCTATTTACTAGGCGGAATGATGAAGAGTAGGACGAAAGCTTTAATCGGTGCTATGGCACAGGAAAGTATGCAG
AAGTATCGTTTTGATAAATGTTTTTTAGGGGCGAATGGTGTACATGAACAGCTTGGTTTTACAACACCAGATCCGGAAGA
GGCGCTTTTAAAGCAAATGGCATTAACATTAGCAAATGAAGGTTATTTCTTAATTGATGAAAGTAAGTTTTCGGAAGTCG
CGTTTGCGAAAATTGCCAATGTTGAAGAGGCAAATATTATTACAAACCATTTAGAAATTGATTTAGAAAAATATAAAAGA
CAAACCAATGTAATTGAGGCTGATAAACAATGA

Upstream 100 bases:

>100_bases
TTTATAACTGTTTGTGATTGTTTTTGATTATTTATGAATGTTTATGGTTGATTTTTGTGATCGTTTTCATTATACTGTAA
TCAAAGAAGAGGTGAATAAA

Downstream 100 bases:

>100_bases
TCTATACAGTAACTTTAAACCCATCTATTGATTATATAGTACAAGTTAATTCCTTAGAGTTAGGCGCAGTAAATCGAGCA
GAAAAAGATATGAAGTTTCC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVVEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
QTNVIEADKQ

Sequences:

>Translated_250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVVEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
QTNVIEADKQ
>Mature_250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVVEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
QTNVIEADKQ

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=31.9444444444444, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=32.5991189427313, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789059, Length=233, Percent_Identity=30.4721030042918, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789829, Length=219, Percent_Identity=30.1369863013699, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=29.7413793103448, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787063, Length=228, Percent_Identity=28.5087719298246, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1790635, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790753, Length=214, Percent_Identity=23.8317757009346, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082344, Length=249, Percent_Identity=24.0963855421687, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=26.0683760683761, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28073; Mature: 28073

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GKGQEPTMVEKSSKNIQIKQQIAKYAASVVEQGDCIYLDAGSTTFEMIPFLINKDVTVVT
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
TTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QTNVIEADKQ
HHCCCCCCCC
>Mature Secondary Structure
MLTPERHQMILQLVKEQKVVKLQQLVERTASSESTIRRDLAQLEKQRLLKRVHGGAAVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GKGQEPTMVEKSSKNIQIKQQIAKYAASVVEQGDCIYLDAGSTTFEMIPFLINKDVTVVT
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
TTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEEANIITNHLEIDLEKYKR
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QTNVIEADKQ
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]