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The map label for this gene is cidA2 [H]

Identifier: 52141736

GI number: 52141736

Start: 3634530

End: 3634784

Strand: Reverse

Name: cidA2 [H]

Synonym: BCZK3510

Alternate gene names: 52141736

Gene position: 3634784-3634530 (Counterclockwise)

Preceding gene: 52141737

Following gene: 52141739

Centisome position: 68.57

GC content: 34.9

Gene sequence:

>255_bases
ATGAAGTACGTGACGCTTTTACTTCAAGTAGGCGTGCTGTATGTATTTAGTTTAGTTGGTACGTGGATTCAAGGAGTATT
CCATTTATCAATGCCAGGAAGTTTAATAGGGATGTTAATGCTTTTTCTACTCCTTTCCACTCGTATTTTACCATTAAAGT
GGTTTGAAGAAGCGACAATCGGTTCGGTGACTATGATTGTAACAGGAATACTCATCAGTATATTTATACCATATGGAACG
AAATTTATATTTTAA

Upstream 100 bases:

>100_bases
AGTAAGTGTCGAACAAATTCAGCTGGGAATGACTAGGTTTGCTGAAACGTTAAATGAGATTTCATAATAGAGAGGCGTAA
TATTGGAATGAGGGAAAGAA

Downstream 100 bases:

>100_bases
ATTGTAATGGAGATGATGCAAGTGACAACATGGTTTATAGTTACATTATTTGTTTTTGGAGCTATTAAAGTATTAGTTTC
TAGTATGCCGACTTCTGTTG

Product: murein hydrolase exporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MKYVTLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGT
KFIF

Sequences:

>Translated_84_residues
MKYVTLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGT
KFIF
>Mature_84_residues
MKYVTLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGT
KFIF

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 9430; Mature: 9430

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVTLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GSVTMIVTGILISIFIPYGTKFIF
HHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MKYVTLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GSVTMIVTGILISIFIPYGTKFIF
HHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]