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The map label for this gene is yisV [H]

Identifier: 52141737

GI number: 52141737

Start: 3634818

End: 3636251

Strand: Reverse

Name: yisV [H]

Synonym: BCZK3511

Alternate gene names: 52141737

Gene position: 3636251-3634818 (Counterclockwise)

Preceding gene: 52141735

Following gene: 52141736

Centisome position: 68.6

GC content: 37.03

Gene sequence:

>1434_bases
ATGGAATGGAAACCAAATCGTGCAGATAAGACACCTGTATATAAACAAATTGCTGATTATATTGAAAGAGGCATTTCTTC
AGGTGAATTTCCTTCTGATAGTAAGTTACCTTCTGAGCGTATATTGGCAAAGGAATTACAGGTGAACCGGAGTACAATAG
TAGCTGCGTATGAAGAATTAAAATCACTTGGAGTAGTAGAACGGCAAAAGGGAAGCGGAACACGGGTTAATAGAGACATA
TGGGGTGTCTCACATAAACGAATACCGAACTGGGGTAGGTACGTGGAGGATGGATCGTTCTTACCTAATGTACCACTCGT
TCAACAAATTCGAACGGAAACGCAAAAAGACGACTTAATTAATTTAGCGAGTGGTGAATTATCACCAGAATTAATTCCAA
GTGATAGATTCCGAACGATCTTGTCGGAGAAAACATTTATGGAAAACCTCGGTTATGACCATCCACTTGGAAATGAAATG
TTGAGAAAAACAATTGTAGCACATGTTCAGCAATATAAACAAATTGAAGCAGATTCGAATTCTATTCTTATTACATCTGG
AGCACAACAAGCACTTAATCTTATCGTTCAGTGCTTATTAAAACCTGGTGATGCGATTGCAATTGAGGACCCTTCGTATT
GTTTCTCATTGCCGATGTTTAAATCTGCTGGTTTAAAAATATTTCATTTACCTGTTGATCAGCATGGAATGAATCCAGAT
GACCTAATTGATTTGCATAAAAAGCATCGTATTCGCATGGTATTTTTAAATCCAGATTATCAAAATCCAACGGGAACTGT
GCTGTCATTAGCAAGACGTAAAAAGATTTTAGAACTGTCTTCTGAATTTGGTATACCGATTGTAGAAGATGATCCGTATA
GTTTAACGTCCTTTAATGGAGAAGTGAATCCAACATTAAAATCAATGGATCAAAACGGGAATGTTCTTTATGTAAGTTCA
TTATCAAAAATTGTTGCATCGGGATTACGTATTGGCTGGGTAATTGGTCCTACGCGTGTAATAGAACGTTTAGCGGATGC
GAAGCAGCAAGTTGATTTTGGGCACAGTGTATTTACGCAGTGGGTGGCAAATCAATTTTTAGAATCAGACGATTTTCATG
CGCATATTACAATGCTTCGTAGACAATTGAAAGAAAGAAGAGATGTATTAATTAGAAAGCTTGAAGAAATATTAGGAGAC
CAGGTTGAATTTTTTGTTCCAGAGGGTGGAATACATTTATGGTGCAAAGTGCAAGGAACGTTTGATGAATATCATTTATT
AGGTGAATCTATACGAAATGGTGTAGCGTTTGTCCCGGGGAGTGTTTTAGGTACTAAAAGTGAATATATTCGTTTTACTT
TTGGGAGAGTAAGTGTCGAACAAATTCAGCTGGGAATGACTAGGTTTGCTGAAACGTTAAATGAGATTTCATAA

Upstream 100 bases:

>100_bases
CCATTTTAGGATGAGAAAATGTGACTAATTAATACTATTTTTACGGTAAATACTGTTAGTAATAAATTGAGGATAGTTAG
CTTTGAAAGGAGGCAACTAT

Downstream 100 bases:

>100_bases
TAGAGAGGCGTAATATTGGAATGAGGGAAAGAAATGAAGTACGTGACGCTTTTACTTCAAGTAGGCGTGCTGTATGTATT
TAGTTTAGTTGGTACGTGGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEELKSLGVVERQKGSGTRVNRDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEM
LRKTIVAHVQQYKQIEADSNSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNGEVNPTLKSMDQNGNVLYVSS
LSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGD
QVEFFVPEGGIHLWCKVQGTFDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVSVEQIQLGMTRFAETLNEIS

Sequences:

>Translated_477_residues
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEELKSLGVVERQKGSGTRVNRDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEM
LRKTIVAHVQQYKQIEADSNSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNGEVNPTLKSMDQNGNVLYVSS
LSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGD
QVEFFVPEGGIHLWCKVQGTFDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVSVEQIQLGMTRFAETLNEIS
>Mature_477_residues
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEELKSLGVVERQKGSGTRVNRDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEM
LRKTIVAHVQQYKQIEADSNSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNGEVNPTLKSMDQNGNVLYVSS
LSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGD
QVEFFVPEGGIHLWCKVQGTFDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVSVEQIQLGMTRFAETLNEIS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=432, Percent_Identity=28.4722222222222, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI33469970, Length=432, Percent_Identity=28.4722222222222, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI56713256, Length=318, Percent_Identity=23.8993710691824, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI56713254, Length=318, Percent_Identity=23.8993710691824, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1790797, Length=440, Percent_Identity=26.3636363636364, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1787710, Length=464, Percent_Identity=25.8620689655172, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788722, Length=276, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=392, Percent_Identity=23.469387755102, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21356535, Length=391, Percent_Identity=21.9948849104859, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53966; Mature: 53966

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KSLGVVERQKGSGTRVNRDIWGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLI
HHCCCCEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEMLRKTIVAHVQQYKQIEADSN
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
EEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHCCCEEEEECCHHCCCCHH
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNG
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCC
EVNPTLKSMDQNGNVLYVSSLSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQ
CCCCHHHHCCCCCCEEEEHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCHHHHHHH
WVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGDQVEFFVPEGGIHLWCKVQGT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECC
FDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVSVEQIQLGMTRFAETLNEIS
HHHHHHHHHHHHCCEEECCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KSLGVVERQKGSGTRVNRDIWGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLI
HHCCCCEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEMLRKTIVAHVQQYKQIEADSN
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
EEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHCCCEEEEECCHHCCCCHH
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNG
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCC
EVNPTLKSMDQNGNVLYVSSLSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQ
CCCCHHHHCCCCCCEEEEHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCHHHHHHH
WVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGDQVEFFVPEGGIHLWCKVQGT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECC
FDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVSVEQIQLGMTRFAETLNEIS
HHHHHHHHHHHHCCEEECCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]