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The map label for this gene is yusP [H]

Identifier: 52141723

GI number: 52141723

Start: 3652844

End: 3654235

Strand: Direct

Name: yusP [H]

Synonym: BCZK3524

Alternate gene names: 52141723

Gene position: 3652844-3654235 (Clockwise)

Preceding gene: 52141724

Following gene: 52141720

Centisome position: 68.91

GC content: 35.92

Gene sequence:

>1392_bases
ATGGATAATACAAATGTGGTTATAAATCGTAAACTCCCTCTTTTTAGTGAAAAGTTAGTCATTCTGATTGCTGGTATCGG
GATGTTCTTATCAACTTTAGATACAGGGATTATTAACATTGCTCTACCTTATTTAGAAAAAGAGTTTCATTCAACAGTAA
CTATAACAGCATGGAGCGTTACCATATATGTTATGGCACTGAGTGCAACTATCCTTTTATTTGGAAAAATTAGTGATCGT
GTAGGTCGTTTTCGAATATGTTTATATGGTTTTTTCATATTTTTAATTAGCTCTATACTATGTGGATTAGCTCAAGAGAT
GTGGCAATTAATTGTATTTCGTGCTATTCAGGGTATTGGTGCTGCTGCATTACAGGCTACATCTGCTGCACTTATTACAA
CTCTTGTCAGTCCTGAAAATCGCAATCATGCATTAGGTACCTTAGGGGTAATGATAGGCTTAGGACCAATTTTAGGTCCT
ACAGCAGGTGGGCTTTTCATTTCATTAGGAAGTTGGCGATGGATTTTTTGGATTAACATCCCTTTATGTTTAATAGGTTT
GTGGGCTTGTTATAAAATTTCTCGATTTATAAAAGAGGAAAAACATCCAGCTCCTATTGATGTGTTAGGAAATATATACT
TTACTTTAAGTGCCTTGTTATTTCTTTTCAGCTTATCTCATGGAGCAAACAAAGTAATGGGAAGTATACCTACTTGGGGG
TATATAATCGCTTCTATTATTTTATTAGGTATTTTCATATTCCATGAATCCAACACTAAGCATCCTATTATAGATGTACA
TTTATTTCTTAACTCAACCTTTATTGTTCCAATACTTGCAACGATAGGATTCGGGGTGGCATCAGCAATTATTTTTATCG
TCCCTCCATATTTTTTACAAAAATTCACGTCATTAACTCCTTTACAAACAGGTTTTGTTTTACTATCAGCCCCACTTGGC
CTAGTAATCTTCTCAAGAATATCTGGGAAGTTCATGGGGCGCTTTGGAACAACCTTATTTATGAGCATAGGTTTAGGAGT
TATGTTTATAGCATTTGTCGGCTTAAGTTTTATTGAAGCACAGTGGTCACCGTATCTATTAGCTAGTGTATTGTTTCTAT
ACGGTATTGGAGGTGGCATTTTCCAACCAGCAAATATCGCTTCAATCATGGCATCTGTTTCAAAAGAAAAACAAGGATCC
ATTGGAGCTGTACAACGCATGTTACAAAATGTGGCAATTGCCTTTGGTGCAGCAGTTGCTGCAACCTTCATGAGTACACA
AAGCTATTTAGGCACAGATGGACTCATCCAAGCCTTTCGATATTCATGGTATATCGCAGGAGGATTATTACTCTTTAATA
CCTTATGCTTCTTAGGATACCGAAAATCTTAA

Upstream 100 bases:

>100_bases
AAGATGGATGGCTTCATTTACAAATGATTATAAATGATGTTTTGTCAACCAGCACACAAATAGATGAACAAGAACATAAT
GAACAGGTAGTGTCAATTTA

Downstream 100 bases:

>100_bases
AATTTTTTCAGTAACAAAAACCGATTTACCTAGGGATAAATCGGTTTTTGTTTAACTAACTGCTTTGCAACAGCCTACTC
AACTAAAAATATAAACACTT

Product: major facilitator family multidrug efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDNTNVVINRKLPLFSEKLVILIAGIGMFLSTLDTGIINIALPYLEKEFHSTVTITAWSVTIYVMALSATILLFGKISDR
VGRFRICLYGFFIFLISSILCGLAQEMWQLIVFRAIQGIGAAALQATSAALITTLVSPENRNHALGTLGVMIGLGPILGP
TAGGLFISLGSWRWIFWINIPLCLIGLWACYKISRFIKEEKHPAPIDVLGNIYFTLSALLFLFSLSHGANKVMGSIPTWG
YIIASIILLGIFIFHESNTKHPIIDVHLFLNSTFIVPILATIGFGVASAIIFIVPPYFLQKFTSLTPLQTGFVLLSAPLG
LVIFSRISGKFMGRFGTTLFMSIGLGVMFIAFVGLSFIEAQWSPYLLASVLFLYGIGGGIFQPANIASIMASVSKEKQGS
IGAVQRMLQNVAIAFGAAVAATFMSTQSYLGTDGLIQAFRYSWYIAGGLLLFNTLCFLGYRKS

Sequences:

>Translated_463_residues
MDNTNVVINRKLPLFSEKLVILIAGIGMFLSTLDTGIINIALPYLEKEFHSTVTITAWSVTIYVMALSATILLFGKISDR
VGRFRICLYGFFIFLISSILCGLAQEMWQLIVFRAIQGIGAAALQATSAALITTLVSPENRNHALGTLGVMIGLGPILGP
TAGGLFISLGSWRWIFWINIPLCLIGLWACYKISRFIKEEKHPAPIDVLGNIYFTLSALLFLFSLSHGANKVMGSIPTWG
YIIASIILLGIFIFHESNTKHPIIDVHLFLNSTFIVPILATIGFGVASAIIFIVPPYFLQKFTSLTPLQTGFVLLSAPLG
LVIFSRISGKFMGRFGTTLFMSIGLGVMFIAFVGLSFIEAQWSPYLLASVLFLYGIGGGIFQPANIASIMASVSKEKQGS
IGAVQRMLQNVAIAFGAAVAATFMSTQSYLGTDGLIQAFRYSWYIAGGLLLFNTLCFLGYRKS
>Mature_463_residues
MDNTNVVINRKLPLFSEKLVILIAGIGMFLSTLDTGIINIALPYLEKEFHSTVTITAWSVTIYVMALSATILLFGKISDR
VGRFRICLYGFFIFLISSILCGLAQEMWQLIVFRAIQGIGAAALQATSAALITTLVSPENRNHALGTLGVMIGLGPILGP
TAGGLFISLGSWRWIFWINIPLCLIGLWACYKISRFIKEEKHPAPIDVLGNIYFTLSALLFLFSLSHGANKVMGSIPTWG
YIIASIILLGIFIFHESNTKHPIIDVHLFLNSTFIVPILATIGFGVASAIIFIVPPYFLQKFTSLTPLQTGFVLLSAPLG
LVIFSRISGKFMGRFGTTLFMSIGLGVMFIAFVGLSFIEAQWSPYLLASVLFLYGIGGGIFQPANIASIMASVSKEKQGS
IGAVQRMLQNVAIAFGAAVAATFMSTQSYLGTDGLIQAFRYSWYIAGGLLLFNTLCFLGYRKS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=434, Percent_Identity=28.110599078341, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081983, Length=422, Percent_Identity=26.0663507109005, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789042, Length=340, Percent_Identity=27.9411764705882, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788710, Length=326, Percent_Identity=27.3006134969325, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788392, Length=440, Percent_Identity=24.0909090909091, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790146, Length=181, Percent_Identity=26.5193370165746, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323735, Length=319, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319770, Length=386, Percent_Identity=25.6476683937824, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321663, Length=149, Percent_Identity=30.8724832214765, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322958, Length=155, Percent_Identity=27.741935483871, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319480, Length=171, Percent_Identity=25.1461988304094, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324954, Length=422, Percent_Identity=24.1706161137441, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325455, Length=135, Percent_Identity=28.1481481481481, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50415; Mature: 50415

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS50850 MFS ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTNVVINRKLPLFSEKLVILIAGIGMFLSTLDTGIINIALPYLEKEFHSTVTITAWSV
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHH
TIYVMALSATILLFGKISDRVGRFRICLYGFFIFLISSILCGLAQEMWQLIVFRAIQGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAALQATSAALITTLVSPENRNHALGTLGVMIGLGPILGPTAGGLFISLGSWRWIFWINI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHCCCCCCCEEEEECCEEEEEEECH
PLCLIGLWACYKISRFIKEEKHPAPIDVLGNIYFTLSALLFLFSLSHGANKVMGSIPTWG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHH
YIIASIILLGIFIFHESNTKHPIIDVHLFLNSTFIVPILATIGFGVASAIIFIVPPYFLQ
HHHHHHHHHHHHHEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KFTSLTPLQTGFVLLSAPLGLVIFSRISGKFMGRFGTTLFMSIGLGVMFIAFVGLSFIEA
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWSPYLLASVLFLYGIGGGIFQPANIASIMASVSKEKQGSIGAVQRMLQNVAIAFGAAVA
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ATFMSTQSYLGTDGLIQAFRYSWYIAGGLLLFNTLCFLGYRKS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDNTNVVINRKLPLFSEKLVILIAGIGMFLSTLDTGIINIALPYLEKEFHSTVTITAWSV
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHH
TIYVMALSATILLFGKISDRVGRFRICLYGFFIFLISSILCGLAQEMWQLIVFRAIQGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAALQATSAALITTLVSPENRNHALGTLGVMIGLGPILGPTAGGLFISLGSWRWIFWINI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHCCCCCCCEEEEECCEEEEEEECH
PLCLIGLWACYKISRFIKEEKHPAPIDVLGNIYFTLSALLFLFSLSHGANKVMGSIPTWG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHH
YIIASIILLGIFIFHESNTKHPIIDVHLFLNSTFIVPILATIGFGVASAIIFIVPPYFLQ
HHHHHHHHHHHHHEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KFTSLTPLQTGFVLLSAPLGLVIFSRISGKFMGRFGTTLFMSIGLGVMFIAFVGLSFIEA
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWSPYLLASVLFLYGIGGGIFQPANIASIMASVSKEKQGSIGAVQRMLQNVAIAFGAAVA
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ATFMSTQSYLGTDGLIQAFRYSWYIAGGLLLFNTLCFLGYRKS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]