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The map label for this gene is fmt [H]

Identifier: 52141724

GI number: 52141724

Start: 3651894

End: 3652844

Strand: Direct

Name: fmt [H]

Synonym: BCZK3523

Alternate gene names: 52141724

Gene position: 3651894-3652844 (Clockwise)

Preceding gene: 52141725

Following gene: 52141723

Centisome position: 68.89

GC content: 32.39

Gene sequence:

>951_bases
ATGATTCGACCTGTAAAGAAAGTCATTTTATTCTCAGAAGTTAATTCAAAATTTGGTTTACCGTTTCTTCAGGAATTAAT
ACAAGAGCCTTCTATTTCCGTAGAAGCTCTTGTCACTAGTCCCGAAGGAAAGTTATGTTCTTATTATATTGGAGAACCTG
ATCAAGTTGATTTAGAAAAAGAAGCCAAGGACATTGGTATTCCCGTGTTACGACCGGATAAACTGAATGATTCTAACACA
GTAGAATTATTAAAAAATTATAATGCTGACTATTTTATTATTGCTAATTACCAAAAAATCTTAAAAGAAGATATTTTATC
TATTCCCAAAGAAGATACTATAAATTTTCATCCAAGCCCATTACCTAGGTATGCTGGATTAGCACCTTTTTTCTGGATGG
CTAAAAATGGAGAAAAAGAAGGTGGCGTTTCATGTATCCAAGTCGTACCAGAAATTGATGCTGGCCCTATTTTAGCTCAA
TTGCCAGTTGTGATGTCAGGGACTGAAACAGCTTTAGAAATTCGAGAGACGCATTTTAAACAATCCATTATTTTACTAAA
ACAAGTTCTTCAAAAAATTAAAAATAATGATTTCACTTCAAAATTGCAGTTATTGTCTAATCGAACCTATTATAGTCAAC
CAAAAGAAGAAGATTATTTTGTAAATTGGGAACAGGATATAGAATCCATACTCCGTACTATTCGCGCTGGGTATCCACAA
GGGGCTTTTGCATTTAATCAATATAATGAAAAAATCCGGATTTTAAGTGCTGAAAGAACAGAATATCCTCAACAAATTCA
AAGTATTGGTGTATTTCGTGAACATAACAATAAAATTCTTGTTTCTACAAAAGATGGATGGCTTCATTTACAAATGATTA
TAAATGATGTTTTGTCAACCAGCACACAAATAGATGAACAAGAACATAATGAACAGGTAGTGTCAATTTAA

Upstream 100 bases:

>100_bases
AATTGCCAGGTGCTCAACAATTACCAGTTCAACCGGGATACGCTATGTTTGATACTATGGCTTGGCAATCTAAAATTGTT
CATGGTAAGTGGTGGTCTGA

Downstream 100 bases:

>100_bases
TGGATAATACAAATGTGGTTATAAATCGTAAACTCCCTCTTTTTAGTGAAAAGTTAGTCATTCTGATTGCTGGTATCGGG
ATGTTCTTATCAACTTTAGA

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIRPVKKVILFSEVNSKFGLPFLQELIQEPSISVEALVTSPEGKLCSYYIGEPDQVDLEKEAKDIGIPVLRPDKLNDSNT
VELLKNYNADYFIIANYQKILKEDILSIPKEDTINFHPSPLPRYAGLAPFFWMAKNGEKEGGVSCIQVVPEIDAGPILAQ
LPVVMSGTETALEIRETHFKQSIILLKQVLQKIKNNDFTSKLQLLSNRTYYSQPKEEDYFVNWEQDIESILRTIRAGYPQ
GAFAFNQYNEKIRILSAERTEYPQQIQSIGVFREHNNKILVSTKDGWLHLQMIINDVLSTSTQIDEQEHNEQVVSI

Sequences:

>Translated_316_residues
MIRPVKKVILFSEVNSKFGLPFLQELIQEPSISVEALVTSPEGKLCSYYIGEPDQVDLEKEAKDIGIPVLRPDKLNDSNT
VELLKNYNADYFIIANYQKILKEDILSIPKEDTINFHPSPLPRYAGLAPFFWMAKNGEKEGGVSCIQVVPEIDAGPILAQ
LPVVMSGTETALEIRETHFKQSIILLKQVLQKIKNNDFTSKLQLLSNRTYYSQPKEEDYFVNWEQDIESILRTIRAGYPQ
GAFAFNQYNEKIRILSAERTEYPQQIQSIGVFREHNNKILVSTKDGWLHLQMIINDVLSTSTQIDEQEHNEQVVSI
>Mature_316_residues
MIRPVKKVILFSEVNSKFGLPFLQELIQEPSISVEALVTSPEGKLCSYYIGEPDQVDLEKEAKDIGIPVLRPDKLNDSNT
VELLKNYNADYFIIANYQKILKEDILSIPKEDTINFHPSPLPRYAGLAPFFWMAKNGEKEGGVSCIQVVPEIDAGPILAQ
LPVVMSGTETALEIRETHFKQSIILLKQVLQKIKNNDFTSKLQLLSNRTYYSQPKEEDYFVNWEQDIESILRTIRAGYPQ
GAFAFNQYNEKIRILSAERTEYPQQIQSIGVFREHNNKILVSTKDGWLHLQMIINDVLSTSTQIDEQEHNEQVVSI

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Escherichia coli, GI1788589, Length=236, Percent_Identity=27.1186440677966, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789683, Length=229, Percent_Identity=23.5807860262009, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 36104; Mature: 36104

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPVKKVILFSEVNSKFGLPFLQELIQEPSISVEALVTSPEGKLCSYYIGEPDQVDLEK
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCHHH
EAKDIGIPVLRPDKLNDSNTVELLKNYNADYFIIANYQKILKEDILSIPKEDTINFHPSP
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCC
LPRYAGLAPFFWMAKNGEKEGGVSCIQVVPEIDAGPILAQLPVVMSGTETALEIRETHFK
CCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHCCEEECCCHHHHHHHHHHHH
QSIILLKQVLQKIKNNDFTSKLQLLSNRTYYSQPKEEDYFVNWEQDIESILRTIRAGYPQ
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCC
GAFAFNQYNEKIRILSAERTEYPQQIQSIGVFREHNNKILVSTKDGWLHLQMIINDVLST
CCCHHHCCCCEEEEEECHHHHHHHHHHHHHHEEECCCEEEEEECCCCEEHHHHHHHHHHH
STQIDEQEHNEQVVSI
HHHCCHHHCCCCCCCC
>Mature Secondary Structure
MIRPVKKVILFSEVNSKFGLPFLQELIQEPSISVEALVTSPEGKLCSYYIGEPDQVDLEK
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCHHH
EAKDIGIPVLRPDKLNDSNTVELLKNYNADYFIIANYQKILKEDILSIPKEDTINFHPSP
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCC
LPRYAGLAPFFWMAKNGEKEGGVSCIQVVPEIDAGPILAQLPVVMSGTETALEIRETHFK
CCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHCCEEECCCHHHHHHHHHHHH
QSIILLKQVLQKIKNNDFTSKLQLLSNRTYYSQPKEEDYFVNWEQDIESILRTIRAGYPQ
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCC
GAFAFNQYNEKIRILSAERTEYPQQIQSIGVFREHNNKILVSTKDGWLHLQMIINDVLST
CCCHHHCCCCEEEEEECHHHHHHHHHHHHHHEEECCCEEEEEECCCCEEHHHHHHHHHHH
STQIDEQEHNEQVVSI
HHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA