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The map label for this gene is appB [H]

Identifier: 51893882

GI number: 51893882

Start: 2957965

End: 2958930

Strand: Reverse

Name: appB [H]

Synonym: STH2744

Alternate gene names: 51893882

Gene position: 2958930-2957965 (Counterclockwise)

Preceding gene: 51893883

Following gene: 51893881

Centisome position: 82.97

GC content: 70.81

Gene sequence:

>966_bases
GTGGCTGGATTCATCCTGCGGCGGCTCCTGCAACTGGTGCCGATGCTGCTGGGCGCCTCCCTGCTCATCTTCGCCGTGAT
CCGCCTCGCGCCGGGCGACCCCTACAGCGGGCTGGTCGATCCGCGGGCCGACCCGGCCAAGATCGAAGAACTGCGCCGGC
GCCACTGCCTGGACTGCCCCCTGCCGCAGCAGTACTGGCGGTGGCTGAGCCATGCGGCGCGGGGCGATCTGGGCACGTCC
ATCCGGTTCCGCATCCCCGTTGCGCAGCTGATCGGCGACCGGCTGGGGCCGAGCATCGCCCTGGGGGTCACGGCCCAGTC
CATCGTGCTGCTCGCCGGCATCCCCTTCGGCATTCTGGCCGCGGTCCGCCGGGGCACGTGGGTCGATGCGGCCGTGACCA
CCTGCTCGCTGGCCTTCCTGGCCATCCCCGCCTTCTTCCTCGGCCTGCTGCTCCTGCGCTTCTTCTCCCTCGGCGGCCTG
CAAGTCCTGCCGTCCGCCGGGTTCACCACGCCGGGCAGTCTGCTCACCGGCCCGGCCCGCTTCCTCGACGCGGCCCGACA
CCTCATCCTGCCGGCCACCGCTCTCGGGGTGACCGGCATCGCAGGGCTGATGAGCCACGTGCGTTCCGCCATGCTGGAGG
TGCTCCGACAGGACTACCTGCGCACGGCCAGGGCCAAGGGGCTGCCCGAGCGGATGGTCATCTACCGTCACGCCCTGCGC
AACGCCCTGATGCCGGTGATCACCCTGCTCGGCCTCAACCTGCCGGCCCTGTTGGGCGGGGCGATCATCACCGAGTCGCT
GTTCCAGTGGCCCGGAGTCGGCCGGCTTACCTACACGGCGCTGCTGGAGCGGGACTACCCGGTGCTGATGGCGCTCAACC
TGCTGTTCGCGGCGCTCACCCTGCTGGGCAGCCTACTGGCGGACGTGGGGTACGCCGCAGTCGATCCCCGGGTGCGCTAT
GAGTGA

Upstream 100 bases:

>100_bases
TCTGGGAGCTCTGGATCGCGTCCGGGCGCCGCTGAGGCCCACGACGGTCGTACAGCTGGGCTTCCCGGACGGCGGCCGGG
TGTGAGGGAGGGACGGGGCG

Downstream 100 bases:

>100_bases
ATCGGGGGGAGTGCTGGTGGCCTGGCGCCGCTTCCGTGCCAACCGGCGGGCGATGCTGGGGCTGTATGTGCTTTTTGCCC
TGATCCTGGCGTCGGCCTGC

Product: oligopeptide ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAGFILRRLLQLVPMLLGASLLIFAVIRLAPGDPYSGLVDPRADPAKIEELRRRHCLDCPLPQQYWRWLSHAARGDLGTS
IRFRIPVAQLIGDRLGPSIALGVTAQSIVLLAGIPFGILAAVRRGTWVDAAVTTCSLAFLAIPAFFLGLLLLRFFSLGGL
QVLPSAGFTTPGSLLTGPARFLDAARHLILPATALGVTGIAGLMSHVRSAMLEVLRQDYLRTARAKGLPERMVIYRHALR
NALMPVITLLGLNLPALLGGAIITESLFQWPGVGRLTYTALLERDYPVLMALNLLFAALTLLGSLLADVGYAAVDPRVRY
E

Sequences:

>Translated_321_residues
MAGFILRRLLQLVPMLLGASLLIFAVIRLAPGDPYSGLVDPRADPAKIEELRRRHCLDCPLPQQYWRWLSHAARGDLGTS
IRFRIPVAQLIGDRLGPSIALGVTAQSIVLLAGIPFGILAAVRRGTWVDAAVTTCSLAFLAIPAFFLGLLLLRFFSLGGL
QVLPSAGFTTPGSLLTGPARFLDAARHLILPATALGVTGIAGLMSHVRSAMLEVLRQDYLRTARAKGLPERMVIYRHALR
NALMPVITLLGLNLPALLGGAIITESLFQWPGVGRLTYTALLERDYPVLMALNLLFAALTLLGSLLADVGYAAVDPRVRY
E
>Mature_320_residues
AGFILRRLLQLVPMLLGASLLIFAVIRLAPGDPYSGLVDPRADPAKIEELRRRHCLDCPLPQQYWRWLSHAARGDLGTSI
RFRIPVAQLIGDRLGPSIALGVTAQSIVLLAGIPFGILAAVRRGTWVDAAVTTCSLAFLAIPAFFLGLLLLRFFSLGGLQ
VLPSAGFTTPGSLLTGPARFLDAARHLILPATALGVTGIAGLMSHVRSAMLEVLRQDYLRTARAKGLPERMVIYRHALRN
ALMPVITLLGLNLPALLGGAIITESLFQWPGVGRLTYTALLERDYPVLMALNLLFAALTLLGSLLADVGYAAVDPRVRYE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=321, Percent_Identity=39.8753894080997, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=40.117994100295, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=33.6448598130841, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=38.5321100917431, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=35.4037267080745, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1788504, Length=370, Percent_Identity=29.7297297297297, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787550, Length=270, Percent_Identity=31.4814814814815, Blast_Score=127, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34700; Mature: 34569

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFILRRLLQLVPMLLGASLLIFAVIRLAPGDPYSGLVDPRADPAKIEELRRRHCLDCP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
LPQQYWRWLSHAARGDLGTSIRFRIPVAQLIGDRLGPSIALGVTAQSIVLLAGIPFGILA
CCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHH
AVRRGTWVDAAVTTCSLAFLAIPAFFLGLLLLRFFSLGGLQVLPSAGFTTPGSLLTGPAR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHCCHHH
FLDAARHLILPATALGVTGIAGLMSHVRSAMLEVLRQDYLRTARAKGLPERMVIYRHALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NALMPVITLLGLNLPALLGGAIITESLFQWPGVGRLTYTALLERDYPVLMALNLLFAALT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LLGSLLADVGYAAVDPRVRYE
HHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure 
AGFILRRLLQLVPMLLGASLLIFAVIRLAPGDPYSGLVDPRADPAKIEELRRRHCLDCP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
LPQQYWRWLSHAARGDLGTSIRFRIPVAQLIGDRLGPSIALGVTAQSIVLLAGIPFGILA
CCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHH
AVRRGTWVDAAVTTCSLAFLAIPAFFLGLLLLRFFSLGGLQVLPSAGFTTPGSLLTGPAR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHCCHHH
FLDAARHLILPATALGVTGIAGLMSHVRSAMLEVLRQDYLRTARAKGLPERMVIYRHALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NALMPVITLLGLNLPALLGGAIITESLFQWPGVGRLTYTALLERDYPVLMALNLLFAALT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LLGSLLADVGYAAVDPRVRYE
HHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]