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The map label for this gene is appC [H]

Identifier: 51893881

GI number: 51893881

Start: 2957118

End: 2957972

Strand: Reverse

Name: appC [H]

Synonym: STH2743

Alternate gene names: 51893881

Gene position: 2957972-2957118 (Counterclockwise)

Preceding gene: 51893882

Following gene: 51893880

Centisome position: 82.95

GC content: 68.89

Gene sequence:

>855_bases
ATGAGTGAATCGGGGGGAGTGCTGGTGGCCTGGCGCCGCTTCCGTGCCAACCGGCGGGCGATGCTGGGGCTGTATGTGCT
TTTTGCCCTGATCCTGGCGTCGGCCTGCGCGCCGCTGTTCACCCACCACGACCCGGATCTGCCGGACATCCGGCAGGCGG
AGCAACCGCCGTCCCGGGAGCACTGGCTGGGGACCGATGAGCTGGGGCGGGACGTCTACGCCCGGCTGCTCTATGGCGGG
CGGGTTTCCCTGACGGTGGGACTCGTCGCTGTCTCCATCTACATGGCGATCGGCGTGGTCCTTGGGGCCGTCGCCGGTTA
CTACGGCGGCGCGGTGGACAGCGCGATCATGCGCCTCACCGATGTGGTCATGATCGTCCCGTTCTTCCCCCTGGCCCTGA
CGATGGCCGCTGCGCTGCGGCCGTCGGTCTACAACACGATGCTCGTCATTGGCCTGCTGGGGTGGACCGGCGTGTGCAGG
CTGGTGAGGGGCGAGTTCCTGACGCTGCGCAGCCGGGAGTACGTGGAGGCGGCCCGGGCTATCGGCGCCAGGGACGGGCG
GATCATCTTCCGGCACATCCTGCCCAACGCGCTGGGGCCGATCCTGGTGGCGGCGACGCTGGGGGTGGGTTCGGCCATCC
TCAGCGAAGCCGGGCTCTCCTTCCTGGGCTTCGGGGTGCAGCAGCCGACGCCCTCGTGGGGAAACATGCTCGCAGCGGCT
CTTTCGTTGAAGGTACTCCTTCGGGAGCCGTGGATCTGGCTGCCGCCGGGGCTCCTGATCTTCGTGGCCGTCCTGGCGGT
GAACTTCGTGGGCGAAGGGCTGCGCGAGGCGTTGGACCCGCGACTGCACCGGTAG

Upstream 100 bases:

>100_bases
CCGGTGCTGATGGCGCTCAACCTGCTGTTCGCGGCGCTCACCCTGCTGGGCAGCCTACTGGCGGACGTGGGGTACGCCGC
AGTCGATCCCCGGGTGCGCT

Downstream 100 bases:

>100_bases
AGGGTTGACCCGAACACAGGTTTGTGCAATAATCGGATATGCCAGACGTGCGCAGCATCGATGGGGGGTGCGGGGTGGCC
CTTCGGCCTGGGTTCCTGCA

Product: oligopeptide ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSESGGVLVAWRRFRANRRAMLGLYVLFALILASACAPLFTHHDPDLPDIRQAEQPPSREHWLGTDELGRDVYARLLYGG
RVSLTVGLVAVSIYMAIGVVLGAVAGYYGGAVDSAIMRLTDVVMIVPFFPLALTMAAALRPSVYNTMLVIGLLGWTGVCR
LVRGEFLTLRSREYVEAARAIGARDGRIIFRHILPNALGPILVAATLGVGSAILSEAGLSFLGFGVQQPTPSWGNMLAAA
LSLKVLLREPWIWLPPGLLIFVAVLAVNFVGEGLREALDPRLHR

Sequences:

>Translated_284_residues
MSESGGVLVAWRRFRANRRAMLGLYVLFALILASACAPLFTHHDPDLPDIRQAEQPPSREHWLGTDELGRDVYARLLYGG
RVSLTVGLVAVSIYMAIGVVLGAVAGYYGGAVDSAIMRLTDVVMIVPFFPLALTMAAALRPSVYNTMLVIGLLGWTGVCR
LVRGEFLTLRSREYVEAARAIGARDGRIIFRHILPNALGPILVAATLGVGSAILSEAGLSFLGFGVQQPTPSWGNMLAAA
LSLKVLLREPWIWLPPGLLIFVAVLAVNFVGEGLREALDPRLHR
>Mature_283_residues
SESGGVLVAWRRFRANRRAMLGLYVLFALILASACAPLFTHHDPDLPDIRQAEQPPSREHWLGTDELGRDVYARLLYGGR
VSLTVGLVAVSIYMAIGVVLGAVAGYYGGAVDSAIMRLTDVVMIVPFFPLALTMAAALRPSVYNTMLVIGLLGWTGVCRL
VRGEFLTLRSREYVEAARAIGARDGRIIFRHILPNALGPILVAATLGVGSAILSEAGLSFLGFGVQQPTPSWGNMLAAAL
SLKVLLREPWIWLPPGLLIFVAVLAVNFVGEGLREALDPRLHR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=274, Percent_Identity=40.8759124087591, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787760, Length=256, Percent_Identity=39.84375, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1787498, Length=275, Percent_Identity=38.9090909090909, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1789964, Length=285, Percent_Identity=41.4035087719298, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=38.75, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788505, Length=257, Percent_Identity=36.1867704280156, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787549, Length=284, Percent_Identity=32.3943661971831, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30725; Mature: 30594

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SESGGVLVAWRRFRANRRAMLGLYVLFALILASACAPLFTHHDPDLPDIRQAEQPPSRE
CCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHH
HWLGTDELGRDVYARLLYGGRVSLTVGLVAVSIYMAIGVVLGAVAGYYGGAVDSAIMRLT
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
DVVMIVPFFPLALTMAAALRPSVYNTMLVIGLLGWTGVCRLVRGEFLTLRSREYVEAARA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGARDGRIIFRHILPNALGPILVAATLGVGSAILSEAGLSFLGFGVQQPTPSWGNMLAAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHH
LSLKVLLREPWIWLPPGLLIFVAVLAVNFVGEGLREALDPRLHR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]