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The map label for this gene is fba [H]

Identifier: 51893821

GI number: 51893821

Start: 2871423

End: 2872277

Strand: Reverse

Name: fba [H]

Synonym: STH2683

Alternate gene names: 51893821

Gene position: 2872277-2871423 (Counterclockwise)

Preceding gene: 51893822

Following gene: 51893820

Centisome position: 80.54

GC content: 65.73

Gene sequence:

>855_bases
ATGACTCTGGTCTCACTGAGGACGCTCTTGGATGCAGCACAGGCGGGCAAGTACGCGGTCGGAGCATTCAACTGCAACAA
CATGGAGGTCGTTCAGGCAATCGTCGCAGCAGCGGAGGAGGCCCGTTCTCCTGTGATTCTGCAGGCGAGCCAGGGGGCCA
TCAAGTACGCGGGCCTTGACTATATCGTGAGCATGGTGAAGGCCGCGGCGGCCAAGGCCACCGTGCCCATGGCGCTCCAC
CTGGACCACGGCACCGACTTCAACACCATCATGGCCTGCATCCGGGCCGGCTTCACGTCGGTGATGTTCGACGGGTCGAA
GTACGAGAAGGAGGAGAACATCGCCCGCACCAAGGAGATCGTCAAGATCGCGCACGCGGTGGGCGTCTCGGTGGAGGGCG
AGATCGGCAAGATCGGCGGCGTGGAGGACGACATCGCCGTCGACGAGCGGGATGCGATGCTCACGCCCGTTCCCGACGCC
ATCGAGTTCTACGAGGCCACCGGGGTGGATGCTCTGGCCATGTCCTTCGGCACCGCCCACGGTCCGTACAAGCTGCCGCC
CAAGCTGGATCTGGACCGCATCGCCGCGGTGCACCAGAAGACCGGCGCCCCGCTGGTGATGCACGGCGGTTCGGGCGTGC
CCGAAGAGGACATGCGCAAGGGCATCGAGCTGGGCATCCGCAAGGTGAACATCGACACCGAGCTGCGGCAGGCCTTCCTG
GCCGAGGTGCGGCGCCAGCTGGCCGAGCGGCCGGACGAGCTCGACCCGCGCAAGATCTTCGCTCCGGCCCGCGAGGTGCT
GAAGGAGCACATCAAGGAGAAGATGCGGCTCTTCGGCTGCGCCGGCAAGGCGTAG

Upstream 100 bases:

>100_bases
AAAGAATCTATAGCTTCTCCGATAGGAAGCAGCCCCACGGCTGGCATAACAGTCCACTTATAAGCAAAGGCGCCCCGTGG
GGGCGGTGGGAGGCAAGACG

Downstream 100 bases:

>100_bases
TGCGGGCACGATAGGAATCGCGATCGCCGTTGGGGAAACTTACCCAACGGCGATTGTTCTTTGCAGTGCATTAAGGAGGG
CACGGAATGCGGCATCTGTT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTLVSLRTLLDAAQAGKYAVGAFNCNNMEVVQAIVAAAEEARSPVILQASQGAIKYAGLDYIVSMVKAAAAKATVPMALH
LDHGTDFNTIMACIRAGFTSVMFDGSKYEKEENIARTKEIVKIAHAVGVSVEGEIGKIGGVEDDIAVDERDAMLTPVPDA
IEFYEATGVDALAMSFGTAHGPYKLPPKLDLDRIAAVHQKTGAPLVMHGGSGVPEEDMRKGIELGIRKVNIDTELRQAFL
AEVRRQLAERPDELDPRKIFAPAREVLKEHIKEKMRLFGCAGKA

Sequences:

>Translated_284_residues
MTLVSLRTLLDAAQAGKYAVGAFNCNNMEVVQAIVAAAEEARSPVILQASQGAIKYAGLDYIVSMVKAAAAKATVPMALH
LDHGTDFNTIMACIRAGFTSVMFDGSKYEKEENIARTKEIVKIAHAVGVSVEGEIGKIGGVEDDIAVDERDAMLTPVPDA
IEFYEATGVDALAMSFGTAHGPYKLPPKLDLDRIAAVHQKTGAPLVMHGGSGVPEEDMRKGIELGIRKVNIDTELRQAFL
AEVRRQLAERPDELDPRKIFAPAREVLKEHIKEKMRLFGCAGKA
>Mature_283_residues
TLVSLRTLLDAAQAGKYAVGAFNCNNMEVVQAIVAAAEEARSPVILQASQGAIKYAGLDYIVSMVKAAAAKATVPMALHL
DHGTDFNTIMACIRAGFTSVMFDGSKYEKEENIARTKEIVKIAHAVGVSVEGEIGKIGGVEDDIAVDERDAMLTPVPDAI
EFYEATGVDALAMSFGTAHGPYKLPPKLDLDRIAAVHQKTGAPLVMHGGSGVPEEDMRKGIELGIRKVNIDTELRQAFLA
EVRRQLAERPDELDPRKIFAPAREVLKEHIKEKMRLFGCAGKA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=284, Percent_Identity=41.1971830985916, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI1789526, Length=283, Percent_Identity=42.4028268551237, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1788072, Length=284, Percent_Identity=36.6197183098592, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1789293, Length=319, Percent_Identity=25.705329153605, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322790, Length=295, Percent_Identity=27.1186440677966, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30615; Mature: 30484

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVSLRTLLDAAQAGKYAVGAFNCNNMEVVQAIVAAAEEARSPVILQASQGAIKYAGLD
CCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHH
YIVSMVKAAAAKATVPMALHLDHGTDFNTIMACIRAGFTSVMFDGSKYEKEENIARTKEI
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCHHHEEECCHHHHHHHHHHHHHHH
VKIAHAVGVSVEGEIGKIGGVEDDIAVDERDAMLTPVPDAIEFYEATGVDALAMSFGTAH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCC
GPYKLPPKLDLDRIAAVHQKTGAPLVMHGGSGVPEEDMRKGIELGIRKVNIDTELRQAFL
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCEEECCCHHHHHHHH
AEVRRQLAERPDELDPRKIFAPAREVLKEHIKEKMRLFGCAGKA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLVSLRTLLDAAQAGKYAVGAFNCNNMEVVQAIVAAAEEARSPVILQASQGAIKYAGLD
CHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHH
YIVSMVKAAAAKATVPMALHLDHGTDFNTIMACIRAGFTSVMFDGSKYEKEENIARTKEI
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCHHHEEECCHHHHHHHHHHHHHHH
VKIAHAVGVSVEGEIGKIGGVEDDIAVDERDAMLTPVPDAIEFYEATGVDALAMSFGTAH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCC
GPYKLPPKLDLDRIAAVHQKTGAPLVMHGGSGVPEEDMRKGIELGIRKVNIDTELRQAFL
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCEEECCCHHHHHHHH
AEVRRQLAERPDELDPRKIFAPAREVLKEHIKEKMRLFGCAGKA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA