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The map label for this gene is yflS [H]

Identifier: 51893774

GI number: 51893774

Start: 2830331

End: 2831749

Strand: Reverse

Name: yflS [H]

Synonym: STH2636

Alternate gene names: 51893774

Gene position: 2831749-2830331 (Counterclockwise)

Preceding gene: 51893781

Following gene: 51893771

Centisome position: 79.41

GC content: 65.19

Gene sequence:

>1419_bases
GTGCGCAACGACGACCGGTCCAAGCTCATCCGCGGTCTGATCTGTGTTGCTGTCGGTCTCATCATCTGGTTCCTGCCTGC
TCCCGGTGATCTGGAGCCCGTGGCCATGCACCTCCTGGGCATCTTTGTCGCGACCATCCTCGGACTGATCCTTCAGCCGC
TTCCCCAGGGGGCCGTTGTGATCACCGCCGTGGCGGTGACGGCGATCACGGGTACCCTGTCGATCGGCGACGCCCTCAAC
GGATTCAAGGACTCCACCGTCTGGCTGATCGTGACGGCCTTCCTCTTCGCCCGGGGCCTGATCAAGACCGGACTGGGCCG
CCGCATCTCCTTCATGCTGGTGAAGCGGTTCGGCAAGTCCACCCTGGGCCTCGGCTACGCCCTGGCGCTGTCGGACACGG
TGCTGGCGCCGGCGACCCCGTCCAACACCGCCCGCGCCGGCGGCATCCTCTTCCCGATCGTCCGTGCGCTCTGCTCCTCG
ATGGGTTCTGAGCCCGGCCCCACCGCCAAGCGGGTCGGCCAGTACCTGATGTACAACTCCTTCCAGATCTGCTGCATCAC
GTCGGCGCTGTTCTTCACGGGCGTGGCCCCCAACTCGCTCATCGCCACGCTGGCCAAGGAGAACTTCGGCTACGAGATCA
CCTGGCTCGGCTGGCTGTGGGCGGCGCTCCTGCCGGGCGTCATCTGCATCGCCATCCTTCCCCGGATTTACTACAAGATT
TTCAATCCGGAGCTGAAGTACTCGCCCGAGGCTCCGGCCCTGGCGGAGAAGGAACTGGCGAAGATGGGCCCGATGAGCAC
GGCCGAAAAAGGCATGCTCGCCGTCTTCCTCCTGACCCTGGTCCTGTGGGCCACCTCCCAGTGGACGAACCTCAACGCGA
CCGCCATCGCGCTGCTCGGCGTCGCCATTCTGCTGGTCATCGGCGTCCTCGACTGGCAGGACGTGCTGGCCGAGAAGGGC
GGCTGGGATGCGCTGATCTGGTTCGGCGGCCTCGTCGGCCTGGCCACCGGCCTCTCCAAGGTCGGCATCATCGGCTGGCT
GGCCTCCATCCTCGAGACCTCCCTGGGTGGCATCTCGTCGTGGTTCCTGGCATTTATCCTGGTTGTTATCGCCTACACCT
ATTCGCACTACTTCATCGCCTCCATGACCGCGCACGCCACGGCGTTCTTCGTGCCCCTGGCCCTGGTGGCCATCAGCGCC
GGTGCGCCTTTGGAGATCACCGTGCTGGTGCTGGGCTTCTTCAACTCCCTGAACGCCGTCATGACCCACTACGGCACCGG
TCCCGCCCCGATCTACTTCGGCGCGGGGTACATCGACCAGGGCACCTGGTGGAAATGGGGCTTCGTCACCAGCCTGATCA
ACCTGGTGGTCTGGCTGGGCGCCGGCAGCCTCTGGTGGAAGGTCATCGGCCTGTGGTAG

Upstream 100 bases:

>100_bases
AGCTACCCGCGGGACTTCGTGATACTGTTCACATAGAACCGGAACCTGCCAGTCCCCAAAGCGTTGGCGCTCGCACTGGT
CATGGACAGGAGGGATTCGT

Downstream 100 bases:

>100_bases
CGCTCCCGGAATGGGCGAGGCCCGGTCGGGTTCCCCGACCGGGCCTCGCGCGCAGGCGGCGCGTGAGGGCCGCGGGCGGT
TGCCCGCGGCTCTGACTCGT

Product: 2-oxoglutarate/malate translocator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MRNDDRSKLIRGLICVAVGLIIWFLPAPGDLEPVAMHLLGIFVATILGLILQPLPQGAVVITAVAVTAITGTLSIGDALN
GFKDSTVWLIVTAFLFARGLIKTGLGRRISFMLVKRFGKSTLGLGYALALSDTVLAPATPSNTARAGGILFPIVRALCSS
MGSEPGPTAKRVGQYLMYNSFQICCITSALFFTGVAPNSLIATLAKENFGYEITWLGWLWAALLPGVICIAILPRIYYKI
FNPELKYSPEAPALAEKELAKMGPMSTAEKGMLAVFLLTLVLWATSQWTNLNATAIALLGVAILLVIGVLDWQDVLAEKG
GWDALIWFGGLVGLATGLSKVGIIGWLASILETSLGGISSWFLAFILVVIAYTYSHYFIASMTAHATAFFVPLALVAISA
GAPLEITVLVLGFFNSLNAVMTHYGTGPAPIYFGAGYIDQGTWWKWGFVTSLINLVVWLGAGSLWWKVIGLW

Sequences:

>Translated_472_residues
MRNDDRSKLIRGLICVAVGLIIWFLPAPGDLEPVAMHLLGIFVATILGLILQPLPQGAVVITAVAVTAITGTLSIGDALN
GFKDSTVWLIVTAFLFARGLIKTGLGRRISFMLVKRFGKSTLGLGYALALSDTVLAPATPSNTARAGGILFPIVRALCSS
MGSEPGPTAKRVGQYLMYNSFQICCITSALFFTGVAPNSLIATLAKENFGYEITWLGWLWAALLPGVICIAILPRIYYKI
FNPELKYSPEAPALAEKELAKMGPMSTAEKGMLAVFLLTLVLWATSQWTNLNATAIALLGVAILLVIGVLDWQDVLAEKG
GWDALIWFGGLVGLATGLSKVGIIGWLASILETSLGGISSWFLAFILVVIAYTYSHYFIASMTAHATAFFVPLALVAISA
GAPLEITVLVLGFFNSLNAVMTHYGTGPAPIYFGAGYIDQGTWWKWGFVTSLINLVVWLGAGSLWWKVIGLW
>Mature_472_residues
MRNDDRSKLIRGLICVAVGLIIWFLPAPGDLEPVAMHLLGIFVATILGLILQPLPQGAVVITAVAVTAITGTLSIGDALN
GFKDSTVWLIVTAFLFARGLIKTGLGRRISFMLVKRFGKSTLGLGYALALSDTVLAPATPSNTARAGGILFPIVRALCSS
MGSEPGPTAKRVGQYLMYNSFQICCITSALFFTGVAPNSLIATLAKENFGYEITWLGWLWAALLPGVICIAILPRIYYKI
FNPELKYSPEAPALAEKELAKMGPMSTAEKGMLAVFLLTLVLWATSQWTNLNATAIALLGVAILLVIGVLDWQDVLAEKG
GWDALIWFGGLVGLATGLSKVGIIGWLASILETSLGGISSWFLAFILVVIAYTYSHYFIASMTAHATAFFVPLALVAISA
GAPLEITVLVLGFFNSLNAVMTHYGTGPAPIYFGAGYIDQGTWWKWGFVTSLINLVVWLGAGSLWWKVIGLW

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=474, Percent_Identity=37.9746835443038, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1786829, Length=492, Percent_Identity=35.5691056910569, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1789444, Length=480, Percent_Identity=35.8333333333333, Blast_Score=271, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50570; Mature: 50570

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNDDRSKLIRGLICVAVGLIIWFLPAPGDLEPVAMHLLGIFVATILGLILQPLPQGAVV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ITAVAVTAITGTLSIGDALNGFKDSTVWLIVTAFLFARGLIKTGLGRRISFMLVKRFGKS
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
TLGLGYALALSDTVLAPATPSNTARAGGILFPIVRALCSSMGSEPGPTAKRVGQYLMYNS
HHCCHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
FQICCITSALFFTGVAPNSLIATLAKENFGYEITWLGWLWAALLPGVICIAILPRIYYKI
CHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FNPELKYSPEAPALAEKELAKMGPMSTAEKGMLAVFLLTLVLWATSQWTNLNATAIALLG
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VAILLVIGVLDWQDVLAEKGGWDALIWFGGLVGLATGLSKVGIIGWLASILETSLGGISS
HHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
WFLAFILVVIAYTYSHYFIASMTAHATAFFVPLALVAISAGAPLEITVLVLGFFNSLNAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MTHYGTGPAPIYFGAGYIDQGTWWKWGFVTSLINLVVWLGAGSLWWKVIGLW
HHHCCCCCCCEEECCCEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MRNDDRSKLIRGLICVAVGLIIWFLPAPGDLEPVAMHLLGIFVATILGLILQPLPQGAVV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ITAVAVTAITGTLSIGDALNGFKDSTVWLIVTAFLFARGLIKTGLGRRISFMLVKRFGKS
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
TLGLGYALALSDTVLAPATPSNTARAGGILFPIVRALCSSMGSEPGPTAKRVGQYLMYNS
HHCCHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
FQICCITSALFFTGVAPNSLIATLAKENFGYEITWLGWLWAALLPGVICIAILPRIYYKI
CHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FNPELKYSPEAPALAEKELAKMGPMSTAEKGMLAVFLLTLVLWATSQWTNLNATAIALLG
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VAILLVIGVLDWQDVLAEKGGWDALIWFGGLVGLATGLSKVGIIGWLASILETSLGGISS
HHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
WFLAFILVVIAYTYSHYFIASMTAHATAFFVPLALVAISAGAPLEITVLVLGFFNSLNAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MTHYGTGPAPIYFGAGYIDQGTWWKWGFVTSLINLVVWLGAGSLWWKVIGLW
HHHCCCCCCCEEECCCEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]