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The map label for this gene is opuCB [H]

Identifier: 51893767

GI number: 51893767

Start: 2822186

End: 2822800

Strand: Reverse

Name: opuCB [H]

Synonym: STH2629

Alternate gene names: 51893767

Gene position: 2822800-2822186 (Counterclockwise)

Preceding gene: 51893768

Following gene: 51893766

Centisome position: 79.16

GC content: 71.06

Gene sequence:

>615_bases
ATGATCACGTGGGCGAAGCTGGCCAGCCTGACCCTGGAGCACCTGCGCCTGTCGCTGTCGGCGGTCCTGCTGGCGGTGCT
GGTGGCCGTGCCCGCCGGCATCCTGCTCAGCCGGATCCGGCGGCTGGCCGACCCGGTCATGGTGGCGCTGGGGCTGTTCC
AGACCCTTCCGGCCATCGCCCTGCTGGCCTTCATGATCCCGCTCATGGGCATCGGCACGAAGCCGGCGCTGACGGCCCTG
TTCCTCTACGCGCTGCTGCCGATTCTGAGCAATACCTACAAGGGCCTGACGGGCGTGGACCCGGCGGTGAAGGAGGCGGC
CCGGGGAATGGGCATGACGGCGCTGCAGATGCTGCTGTCGGTGGAGCTGCCCCTGGCCTTCCGGGTGATCATGAGCGGCG
TCCGCACCTCGACCGTCCTGATCATCGGCTGGGCGACGCTGGGCGCCTACGTCGGCGCCGGCGGGCTGGGCGAGCCGATC
GTCAGCGGCTTCGCCACGGTCTCGCCCCGGCTGATCCTGGCCGGGGGCGTTCCGGTGACGCTCATGGCCCTTCTGGCGGA
CTTCCTCCTGGGCCGCCTGGAGCGCCGGGTCACGCCCCGCGGGCTTCAGGTGTAG

Upstream 100 bases:

>100_bases
TGCCGGTGGTGGATGAGCAGGGCCGGCTGCAGGGGCTGGTCACCAACACGTCGCTGGTGGGCACCCTTTCCCGCGCCGAG
CGGGCCGGGGGGGCGACCGC

Downstream 100 bases:

>100_bases
AAAGGGGGAAGGCCCGCCGTGGAACTGATGCAGGAACTGGTTGTCTACGTGAACGCACACTGGCCCAGGCTGCTGGGCCT
GACCATTCAGCACGTCAAGC

Product: glycine betaine/carnitine/choline ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MITWAKLASLTLEHLRLSLSAVLLAVLVAVPAGILLSRIRRLADPVMVALGLFQTLPAIALLAFMIPLMGIGTKPALTAL
FLYALLPILSNTYKGLTGVDPAVKEAARGMGMTALQMLLSVELPLAFRVIMSGVRTSTVLIIGWATLGAYVGAGGLGEPI
VSGFATVSPRLILAGGVPVTLMALLADFLLGRLERRVTPRGLQV

Sequences:

>Translated_204_residues
MITWAKLASLTLEHLRLSLSAVLLAVLVAVPAGILLSRIRRLADPVMVALGLFQTLPAIALLAFMIPLMGIGTKPALTAL
FLYALLPILSNTYKGLTGVDPAVKEAARGMGMTALQMLLSVELPLAFRVIMSGVRTSTVLIIGWATLGAYVGAGGLGEPI
VSGFATVSPRLILAGGVPVTLMALLADFLLGRLERRVTPRGLQV
>Mature_204_residues
MITWAKLASLTLEHLRLSLSAVLLAVLVAVPAGILLSRIRRLADPVMVALGLFQTLPAIALLAFMIPLMGIGTKPALTAL
FLYALLPILSNTYKGLTGVDPAVKEAARGMGMTALQMLLSVELPLAFRVIMSGVRTSTVLIIGWATLGAYVGAGGLGEPI
VSGFATVSPRLILAGGVPVTLMALLADFLLGRLERRVTPRGLQV

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=193, Percent_Identity=41.4507772020725, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1788451, Length=197, Percent_Identity=35.0253807106599, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789033, Length=178, Percent_Identity=32.0224719101124, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 21392; Mature: 21392

Theoretical pI: Translated: 11.42; Mature: 11.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITWAKLASLTLEHLRLSLSAVLLAVLVAVPAGILLSRIRRLADPVMVALGLFQTLPAIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAFMIPLMGIGTKPALTALFLYALLPILSNTYKGLTGVDPAVKEAARGMGMTALQMLLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHH
VELPLAFRVIMSGVRTSTVLIIGWATLGAYVGAGGLGEPIVSGFATVSPRLILAGGVPVT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHHH
LMALLADFLLGRLERRVTPRGLQV
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MITWAKLASLTLEHLRLSLSAVLLAVLVAVPAGILLSRIRRLADPVMVALGLFQTLPAIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAFMIPLMGIGTKPALTALFLYALLPILSNTYKGLTGVDPAVKEAARGMGMTALQMLLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHH
VELPLAFRVIMSGVRTSTVLIIGWATLGAYVGAGGLGEPIVSGFATVSPRLILAGGVPVT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHHH
LMALLADFLLGRLERRVTPRGLQV
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]