Click here to switch to the map view.

The map label for this gene is murC [H]

Identifier: 51599068

GI number: 51599068

Start: 865527

End: 866933

Strand: Direct

Name: murC [H]

Synonym: BG0842

Alternate gene names: 51599068

Gene position: 865527-866933 (Clockwise)

Preceding gene: 51599067

Following gene: 51599069

Centisome position: 95.72

GC content: 25.73

Gene sequence:

>1407_bases
ATGAAGGTTGATTTTGACAGTTTGAATAATATTTTTTTTGTAGGAATAAAGGGAAGCGGAGTTTGTTCTCTGGCTTGTTT
TTTAAATTCAAAAGGATATTTTGTAGAAGGAGTAGATGTTCCTGATAAATTTTATACTGATGATATTTTAAATAATAATG
AAATATCTTATTATGAAAATATTTATGAGTTTTCATTAAAAGAGCTTGATAGATCTTTTGATTTAATAGTATATTCTTCA
GCTTATGATAAGGACGGTTTGCAAGTTTTGCTTGAAGCAAAAGAATTGAATATACCTATTTTATCTTATTCTGAGGTTCT
TGGTGAGCTTTCTAGAAAGCACTATAGTATTGGAATTGCAGGTTCTCACGGTAAAACTACCACTACGGCATTTTTAGGTA
TTCTTTTTGATAAATTAGGATTAAATCCTAATGTTATTGTGGGATCAAGTGTTAAAGATTTTGGAGATAATTCTGCAATA
GCCGGCATTAGCGATATTTTTATTGTTGAGACTTGTGAGTATAAAAAACATTTTTTATATTTTAGTCCTAATATGCTCAT
TTTAACCAATGTTGACTATGAGCATGTTGATTTTTTTAAAAATTATGAGGCCCTTGAAGATGCTTTTTTACAATATATTA
ATAATTTGAAGAAAAATGGAATATTAATAATTAATTCTGATGATAAGAATTTGCTTAAAATTAAAAGTCAAATCAATAGA
GAAGATATAAATATTTTTAGCTTTGGATCTAGAGATTTGTCCAATTTTCAAATAAGTAACATTGTAGTTAAGAATGAATA
TTTTTGTTTTTCTTTTTTAGGCTTATACAATATTGAACTTAGGACTGTCTTATTTCATAATATATTAAATTTTTCAGCAG
CGCTTTTAGCTTTAAATCTTTTTTTAGAAAGTAATGGAAAATCAATTTTTGATTTTGAAGAAGTAGTAAAGAGAGTTGCA
AAAAATTATAGTGGTATAAAAAGAAGGTCTGAACTTATTAAAGAGAAAAAGGGAGTAATTTACATGGATGATTATGCTCA
TCATCCTAGGGAGATTAGAGCTACTCTTTTTGGTATTAAAAATTTCTATAAGAACAAACGTATAATTTTGGATTTCATGC
CCCATACTTTCACAAGAACAAAAGAATTTTTTGATGATTTTGTTGAAGTTCTTAATATTGCTGATGTATTAATTTTGCAC
AATATATATCTTTCTAACAGGGAGAATTTTAATCCAGATGAACTTTCTTTTAAATTGTTTTTAAATATTAAAAAAATAAA
TAAAAATACTTATTTTTTTAAAGATGTTAAAGATTCTATTAACTTTATAAAGAGTTTACTAATATCTGGAGATTTGTTTA
TTACAATGGGTGCTGGCAATAATTTTATTTTACACGATTTTTTGTAA

Upstream 100 bases:

>100_bases
ATTATTACTAACGTGCTTAAGTATACAATAATTAATATATCATCTATTGATATAGTTATACATAAATTTTATGACAAAAA
AGATTATTTAGAAGAGAGTT

Downstream 100 bases:

>100_bases
GGGTATTATAGTGAAAAGCATGACGGGATTTTTTCATTTGGAAAAGATAATTGGCAACTATATGTTTAGTGTTAATTTAA
AGTCTTATAATGGAAAATTT

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKVDFDSLNNIFFVGIKGSGVCSLACFLNSKGYFVEGVDVPDKFYTDDILNNNEISYYENIYEFSLKELDRSFDLIVYSS
AYDKDGLQVLLEAKELNIPILSYSEVLGELSRKHYSIGIAGSHGKTTTTAFLGILFDKLGLNPNVIVGSSVKDFGDNSAI
AGISDIFIVETCEYKKHFLYFSPNMLILTNVDYEHVDFFKNYEALEDAFLQYINNLKKNGILIINSDDKNLLKIKSQINR
EDINIFSFGSRDLSNFQISNIVVKNEYFCFSFLGLYNIELRTVLFHNILNFSAALLALNLFLESNGKSIFDFEEVVKRVA
KNYSGIKRRSELIKEKKGVIYMDDYAHHPREIRATLFGIKNFYKNKRIILDFMPHTFTRTKEFFDDFVEVLNIADVLILH
NIYLSNRENFNPDELSFKLFLNIKKINKNTYFFKDVKDSINFIKSLLISGDLFITMGAGNNFILHDFL

Sequences:

>Translated_468_residues
MKVDFDSLNNIFFVGIKGSGVCSLACFLNSKGYFVEGVDVPDKFYTDDILNNNEISYYENIYEFSLKELDRSFDLIVYSS
AYDKDGLQVLLEAKELNIPILSYSEVLGELSRKHYSIGIAGSHGKTTTTAFLGILFDKLGLNPNVIVGSSVKDFGDNSAI
AGISDIFIVETCEYKKHFLYFSPNMLILTNVDYEHVDFFKNYEALEDAFLQYINNLKKNGILIINSDDKNLLKIKSQINR
EDINIFSFGSRDLSNFQISNIVVKNEYFCFSFLGLYNIELRTVLFHNILNFSAALLALNLFLESNGKSIFDFEEVVKRVA
KNYSGIKRRSELIKEKKGVIYMDDYAHHPREIRATLFGIKNFYKNKRIILDFMPHTFTRTKEFFDDFVEVLNIADVLILH
NIYLSNRENFNPDELSFKLFLNIKKINKNTYFFKDVKDSINFIKSLLISGDLFITMGAGNNFILHDFL
>Mature_468_residues
MKVDFDSLNNIFFVGIKGSGVCSLACFLNSKGYFVEGVDVPDKFYTDDILNNNEISYYENIYEFSLKELDRSFDLIVYSS
AYDKDGLQVLLEAKELNIPILSYSEVLGELSRKHYSIGIAGSHGKTTTTAFLGILFDKLGLNPNVIVGSSVKDFGDNSAI
AGISDIFIVETCEYKKHFLYFSPNMLILTNVDYEHVDFFKNYEALEDAFLQYINNLKKNGILIINSDDKNLLKIKSQINR
EDINIFSFGSRDLSNFQISNIVVKNEYFCFSFLGLYNIELRTVLFHNILNFSAALLALNLFLESNGKSIFDFEEVVKRVA
KNYSGIKRRSELIKEKKGVIYMDDYAHHPREIRATLFGIKNFYKNKRIILDFMPHTFTRTKEFFDDFVEVLNIADVLILH
NIYLSNRENFNPDELSFKLFLNIKKINKNTYFFKDVKDSINFIKSLLISGDLFITMGAGNNFILHDFL

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=444, Percent_Identity=27.4774774774775, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1790680, Length=475, Percent_Identity=23.5789473684211, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 53886; Mature: 53886

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDFDSLNNIFFVGIKGSGVCSLACFLNSKGYFVEGVDVPDKFYTDDILNNNEISYYEN
CCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHCCCCCCHHHHH
IYEFSLKELDRSFDLIVYSSAYDKDGLQVLLEAKELNIPILSYSEVLGELSRKHYSIGIA
HHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEHHHCCCCEEEHHHHHHHHHHCEEEEEEE
GSHGKTTTTAFLGILFDKLGLNPNVIVGSSVKDFGDNSAIAGISDIFIVETCEYKKHFLY
CCCCCHHHHHHHHHHHHHHCCCCCEEECCCCHHCCCCCCCCCCCEEEEEEEECCCCEEEE
FSPNMLILTNVDYEHVDFFKNYEALEDAFLQYINNLKKNGILIINSDDKNLLKIKSQINR
ECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCC
EDINIFSFGSRDLSNFQISNIVVKNEYFCFSFLGLYNIELRTVLFHNILNFSAALLALNL
CCCEEEEECCCCCCCEEEEEEEEECCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FLESNGKSIFDFEEVVKRVAKNYSGIKRRSELIKEKKGVIYMDDYAHHPREIRATLFGIK
HEECCCCEEECHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHH
NFYKNKRIILDFMPHTFTRTKEFFDDFVEVLNIADVLILHNIYLSNRENFNPDELSFKLF
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEE
LNIKKINKNTYFFKDVKDSINFIKSLLISGDLFITMGAGNNFILHDFL
EEEEEECCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCC
>Mature Secondary Structure
MKVDFDSLNNIFFVGIKGSGVCSLACFLNSKGYFVEGVDVPDKFYTDDILNNNEISYYEN
CCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHCCCCCCHHHHH
IYEFSLKELDRSFDLIVYSSAYDKDGLQVLLEAKELNIPILSYSEVLGELSRKHYSIGIA
HHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEHHHCCCCEEEHHHHHHHHHHCEEEEEEE
GSHGKTTTTAFLGILFDKLGLNPNVIVGSSVKDFGDNSAIAGISDIFIVETCEYKKHFLY
CCCCCHHHHHHHHHHHHHHCCCCCEEECCCCHHCCCCCCCCCCCEEEEEEEECCCCEEEE
FSPNMLILTNVDYEHVDFFKNYEALEDAFLQYINNLKKNGILIINSDDKNLLKIKSQINR
ECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCC
EDINIFSFGSRDLSNFQISNIVVKNEYFCFSFLGLYNIELRTVLFHNILNFSAALLALNL
CCCEEEEECCCCCCCEEEEEEEEECCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FLESNGKSIFDFEEVVKRVAKNYSGIKRRSELIKEKKGVIYMDDYAHHPREIRATLFGIK
HEECCCCEEECHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHH
NFYKNKRIILDFMPHTFTRTKEFFDDFVEVLNIADVLILHNIYLSNRENFNPDELSFKLF
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEE
LNIKKINKNTYFFKDVKDSINFIKSLLISGDLFITMGAGNNFILHDFL
EEEEEECCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA