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The map label for this gene is cysS [H]

Identifier: 51598852

GI number: 51598852

Start: 623917

End: 625359

Strand: Direct

Name: cysS [H]

Synonym: BG0612

Alternate gene names: 51598852

Gene position: 623917-625359 (Clockwise)

Preceding gene: 51598850

Following gene: 51598853

Centisome position: 69.0

GC content: 27.79

Gene sequence:

>1443_bases
ATGATTTTAAAATTATATAATACTAGAACAAAGGATTTTTCAGAATTAGCAAATTTTTCTGATGTTAAAGTGTATGCTTG
CGGGCCCACTGTTTATAATTACGCTCACATTGGAAATTTTAGAACTTATATTTTTGGAGATTTGTTAATTAAAACTTTAA
GGTTTTTAGGGTATAAAGTTAATTATGCAATGAATATTACAGATATTGGGCATTTAACAGGTGATCTTGATGATGGAGAA
GATAAAGTTGCTAAAACGGCAAGAGAGAAAGGCCTTACAGTTTATGAGATTAGTAAATTTTTTACGGAAGCTTTTTTTAA
GGATTGTAAAAAATTAAACGTTGTATATCCCGATAAAGTTCTTATTGCAAGTAAACATATTCCTAATATGATAGAGGTTA
TTAAAATTCTTGAAGAAAAAAAATTTACTTATTTTTCTAATGGCAATGTGTATTTTGATACTTCTTGTTTTAAAAGCTAT
GGTGAGATGGCTGGCATTGATTTGATTGATAAAGATATGGCTTTTTCCAGGGTTGATATTGATAAATTTAAAAGAAATAA
AACCGATTTTGTTCTGTGGTTTACTAATTCTAAATTTAAAGATCAGGAAATGAAATGGGATTCTCCTTGGGGATTTGGTT
ATCCGAGTTGGCATTTGGAGTGCGCCGCTATGAATTTGGAGTATTTCAAAGATACACTTGATATTCATTTAGGCGGAGTT
GATCATATTGGAGTTCATCATATAAATGAAATAGCAATAGTAGAGTGTTTTTTGAATAAGAAATGGTGTGATATTTTTGT
TCATGGAGAATTTTTGATCATGGATTATAACAAGATGTCAAAGTCACATGGGAATTTTATTACAGTTAAAGGCTTAGAAG
AACAAAATTTTTCTCCTCTTGATTTTAGGTATTTATGTTTAACATCACACTACAGGAATCAATTAAAATTTTCATTTAAT
AATCTTAAAGCAAGTAAGATTGCTAGGGAAAATATGATAAACAGGCTAAGCTATTTTTATGCATCTTTAGATCCAGCTGA
TTTAAATATGCTTAATAAAGATTTAAAAAATTTTGGTTTTAGTATAGAAAAAGAATATTATGATTCTTTTGTAGAAAAAG
TTTCTTTTGATTTAAATGTTTCTAAAGGATTGGCTTTACTTTGGGAGGTAATTAAATCTGAAAATCTAGGCTTTGTTTCA
AAGCTTAAATTAGCTTTTATTTTTGATGAGATTATATCGCTTAATTTAAGAGAAGAAATTTTAAAAAAATCAGAAAATCA
TAATATAGTTATTGATGAGAATATGAAAATTTTGCTTGAAGAAAGAAGAATAGCTAAATGTGAAAAAAATTTTAAGCGTG
CAGATGAAATTAGGGATTTTTTTGCTAAAAAAGGTTTTGTTTTGATTGATACCAAGGAAGGAACTAAAGTTAAAAGAGGC
TAG

Upstream 100 bases:

>100_bases
GAGGCTTTATATTGATTTTTTCAAAAAAATTATTTAGTCTTTTAATCATACTTACTTAATAATAAATTAGACTTTGTATT
TTTTCAATTTTGAGAAATGT

Downstream 100 bases:

>100_bases
TATTTGGCTATTTTTTTTAAAAACAAATATTTTCATTTAAGTTTAATTTTTATTATTTTTTTATTTTTGTTTGTTTTTTC
TGGATTTTTATTTTATTCAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MILKLYNTRTKDFSELANFSDVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGE
DKVAKTAREKGLTVYEISKFFTEAFFKDCKKLNVVYPDKVLIASKHIPNMIEVIKILEEKKFTYFSNGNVYFDTSCFKSY
GEMAGIDLIDKDMAFSRVDIDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDTLDIHLGGV
DHIGVHHINEIAIVECFLNKKWCDIFVHGEFLIMDYNKMSKSHGNFITVKGLEEQNFSPLDFRYLCLTSHYRNQLKFSFN
NLKASKIARENMINRLSYFYASLDPADLNMLNKDLKNFGFSIEKEYYDSFVEKVSFDLNVSKGLALLWEVIKSENLGFVS
KLKLAFIFDEIISLNLREEILKKSENHNIVIDENMKILLEERRIAKCEKNFKRADEIRDFFAKKGFVLIDTKEGTKVKRG

Sequences:

>Translated_480_residues
MILKLYNTRTKDFSELANFSDVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGE
DKVAKTAREKGLTVYEISKFFTEAFFKDCKKLNVVYPDKVLIASKHIPNMIEVIKILEEKKFTYFSNGNVYFDTSCFKSY
GEMAGIDLIDKDMAFSRVDIDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDTLDIHLGGV
DHIGVHHINEIAIVECFLNKKWCDIFVHGEFLIMDYNKMSKSHGNFITVKGLEEQNFSPLDFRYLCLTSHYRNQLKFSFN
NLKASKIARENMINRLSYFYASLDPADLNMLNKDLKNFGFSIEKEYYDSFVEKVSFDLNVSKGLALLWEVIKSENLGFVS
KLKLAFIFDEIISLNLREEILKKSENHNIVIDENMKILLEERRIAKCEKNFKRADEIRDFFAKKGFVLIDTKEGTKVKRG
>Mature_480_residues
MILKLYNTRTKDFSELANFSDVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGE
DKVAKTAREKGLTVYEISKFFTEAFFKDCKKLNVVYPDKVLIASKHIPNMIEVIKILEEKKFTYFSNGNVYFDTSCFKSY
GEMAGIDLIDKDMAFSRVDIDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDTLDIHLGGV
DHIGVHHINEIAIVECFLNKKWCDIFVHGEFLIMDYNKMSKSHGNFITVKGLEEQNFSPLDFRYLCLTSHYRNQLKFSFN
NLKASKIARENMINRLSYFYASLDPADLNMLNKDLKNFGFSIEKEYYDSFVEKVSFDLNVSKGLALLWEVIKSENLGFVS
KLKLAFIFDEIISLNLREEILKKSENHNIVIDENMKILLEERRIAKCEKNFKRADEIRDFFAKKGFVLIDTKEGTKVKRG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=324, Percent_Identity=34.5679012345679, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI62240992, Length=244, Percent_Identity=33.6065573770492, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI303304987, Length=244, Percent_Identity=33.6065573770492, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI10835051, Length=243, Percent_Identity=33.7448559670782, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI21269877, Length=244, Percent_Identity=33.6065573770492, Blast_Score=132, Evalue=8e-31,
Organism=Escherichia coli, GI1786737, Length=492, Percent_Identity=32.3170731707317, Blast_Score=229, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17509795, Length=252, Percent_Identity=32.9365079365079, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17509797, Length=252, Percent_Identity=32.9365079365079, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324082, Length=347, Percent_Identity=29.6829971181556, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19922218, Length=508, Percent_Identity=29.7244094488189, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19922364, Length=243, Percent_Identity=31.2757201646091, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56024; Mature: 56024

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKLYNTRTKDFSELANFSDVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKV
CEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHCEEE
NYAMNITDIGHLTGDLDDGEDKVAKTAREKGLTVYEISKFFTEAFFKDCKKLNVVYPDKV
EEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCEECCCEE
LIASKHIPNMIEVIKILEEKKFTYFSNGNVYFDTSCFKSYGEMAGIDLIDKDMAFSRVDI
EEECCCCCHHHHHHHHHHHCCEEEEECCCEEEECHHHHHHHHHCCCCEECCCCCHHHCCH
DKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDTLDIHLGGV
HHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHEEEECCC
DHIGVHHINEIAIVECFLNKKWCDIFVHGEFLIMDYNKMSKSHGNFITVKGLEEQNFSPL
CCCCHHHCCCEEEEEEECCCCEEEEEEECEEEEEECHHHCCCCCCEEEEECCCCCCCCCC
DFRYLCLTSHYRNQLKFSFNNLKASKIARENMINRLSYFYASLDPADLNMLNKDLKNFGF
CEEEEEEEHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
SIEKEYYDSFVEKVSFDLNVSKGLALLWEVIKSENLGFVSKLKLAFIFDEIISLNLREEI
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHH
LKKSENHNIVIDENMKILLEERRIAKCEKNFKRADEIRDFFAKKGFVLIDTKEGTKVKRG
HHCCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MILKLYNTRTKDFSELANFSDVKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKV
CEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHCEEE
NYAMNITDIGHLTGDLDDGEDKVAKTAREKGLTVYEISKFFTEAFFKDCKKLNVVYPDKV
EEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCEECCCEE
LIASKHIPNMIEVIKILEEKKFTYFSNGNVYFDTSCFKSYGEMAGIDLIDKDMAFSRVDI
EEECCCCCHHHHHHHHHHHCCEEEEECCCEEEECHHHHHHHHHCCCCEECCCCCHHHCCH
DKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDTLDIHLGGV
HHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHEEEECCC
DHIGVHHINEIAIVECFLNKKWCDIFVHGEFLIMDYNKMSKSHGNFITVKGLEEQNFSPL
CCCCHHHCCCEEEEEEECCCCEEEEEEECEEEEEECHHHCCCCCCEEEEECCCCCCCCCC
DFRYLCLTSHYRNQLKFSFNNLKASKIARENMINRLSYFYASLDPADLNMLNKDLKNFGF
CEEEEEEEHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
SIEKEYYDSFVEKVSFDLNVSKGLALLWEVIKSENLGFVSKLKLAFIFDEIISLNLREEI
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHH
LKKSENHNIVIDENMKILLEERRIAKCEKNFKRADEIRDFFAKKGFVLIDTKEGTKVKRG
HHCCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA