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The map label for this gene is selA

Identifier: 51598216

GI number: 51598216

Start: 4693927

End: 4695315

Strand: Direct

Name: selA

Synonym: YPTB3931

Alternate gene names: 51598216

Gene position: 4693927-4695315 (Clockwise)

Preceding gene: 51598215

Following gene: 51598217

Centisome position: 98.93

GC content: 54.72

Gene sequence:

>1389_bases
ATGAGCGCAGAACCACACCCATTATATCGCCAGTTACCGGCCATTGATCGCTTACTGAATGAGCCTGAAATGGCCCCTTT
ATTGGCGGAGTATGGCCCCGTTCTTTTGGCCGATACCCTACGTCAATTACAGGCAGAAGCTCGTGAATATATCGGTCAAT
TTCATACTCTGGCTGATTGGTGTGCGGACTGGCCTGCCGCTTTACGTCAACGATTGAATCAACGGCAACCCGCGTTAAAA
CCTGTGTTTAATCTTACTGGCACGGTGCTGCACACCAATTTGGGCCGTGCACCGCTGGCAGAATCTGCTATCGCGGCGGT
GACCGATGCCATGCGAAGTGCGGTCACCTTGGAATACTCCTTAGAGGGCGCGGGCCGTGGGCACCGTGATCGGGCTGTCG
CCGATTTACTCTGTGCCCTGACCGGTGCGGAAGATGCCTGTATCGTCAATAACAATGCGGCGGCGGTCTTCTTGTTGTTA
ACGGTCATGGCGGCGGGCAAGCAAGTCGTGGTCTCCCGTGGTGAACTGGTCGAGATTGGCGGTGCGTTTCGTATTCCTGA
TGTCATGCGTCAGGCAGGGTGTGATCTGGTCGAAGTGGGTACCACGAACCGAACACATCTGAAAGATTATCGGCAGGCCA
TCAATGAAAATACGGGTCTGCTGATGAAAGTTCATACCAGCAATTACAGTATCGAGGGTTTCACGGCCGCAGTATCCGAA
CAGCAACTGGCGGCATTGGGGCAAGAGTGTTCCATCCCGACCGCGACCGATTTAGGCAGTGGTTCGCTGGTGGATATGAC
CCGTTACGGTTTACCCGCCGAGCCCATGCCACAACAGTTGATTGCGGCAGGCGTAGATTTAGTGACCTTCTCCGGTGATA
AACTGTTAGGTGGGCCGCAAGCGGGGATCATTCTCGGTAAAAAACAGTGGATTGAGCGGTTACAGCAACATCCGCTGAAG
CGAGCATTGCGGGCCGATAAAATGACACTGGCAGCTTTGGACGCCACCTTGCGCCTCTATCAGCAGCCAGATCGGTTGGT
TGAACAACTGCCATCTCTGCGGCTACTGACCCGCCCCGCCTCAGAGATTGCCGCGTGTGCACAACGCCTGCTGGCCCCAC
TGATTGCCTGTTATGGCACAGATTTCACTTTGGATATTGAATCATGTTGGTCACAAATTGGCAGTGGTTCGCTGCCGGTT
GATCGCTTGCCCAGTTGGGCGCTGACGTTTACGCCTAAAGATGGGCGCGGTAGTACATTGGAAGCCTTAACGGCGCGTTG
GCGCACACTGACGAAGCCGGTCATTGGTCGTGTGGCTGATGGGCGTTTGTGGCTGGATTTACGCTGTCTGGAGGATGAGG
CGGCGTTGCTAAGGGAATTGGCATCATGA

Upstream 100 bases:

>100_bases
AAGGTCAATGACCAATCAGTGATGGGGGGTGAGGGCAATCAACGCACAGGCAACTCGACGTATGGCGGGTATATCGTTTA
ATTAATTTGTTTGAGTGACT

Downstream 100 bases:

>100_bases
TTATTGTCACCGCAGGCCATGTCGATCATGGCAAAACCACACTTTTACAGGCCATTACCGGGGTCAATGCGGATCGGTTG
CCGGAAGAGAAGCAGCGGGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADWCADWPAALRQRLNQRQPALK
PVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYSLEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLL
TVMAAGKQVVVSRGELVEIGGAFRIPDVMRQAGCDLVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQAGIILGKKQWIERLQQHPLK
RALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPASEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPV
DRLPSWALTFTPKDGRGSTLEALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS

Sequences:

>Translated_462_residues
MSAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADWCADWPAALRQRLNQRQPALK
PVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYSLEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLL
TVMAAGKQVVVSRGELVEIGGAFRIPDVMRQAGCDLVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQAGIILGKKQWIERLQQHPLK
RALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPASEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPV
DRLPSWALTFTPKDGRGSTLEALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS
>Mature_461_residues
SAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADWCADWPAALRQRLNQRQPALKP
VFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYSLEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLLT
VMAAGKQVVVSRGELVEIGGAFRIPDVMRQAGCDLVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSEQ
QLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQAGIILGKKQWIERLQQHPLKR
ALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPASEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPVD
RLPSWALTFTPKDGRGSTLEALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family

Homologues:

Organism=Escherichia coli, GI2367248, Length=461, Percent_Identity=69.1973969631237, Blast_Score=602, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELA_YERP3 (A7FP80)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001403058.1
- ProteinModelPortal:   A7FP80
- STRING:   A7FP80
- GeneID:   5388285
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_4115
- eggNOG:   COG1921
- HOGENOM:   HBG564950
- OMA:   KRGDRDD
- ProtClustDB:   PRK04311
- BioCyc:   YPSE349747:YPSIP31758_4115-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00423
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534
- Gene3D:   G3DSA:3.40.640.10
- TIGRFAMs:   TIGR00474

Pfam domain/function: PF03841 SelA; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.9.1.1

Molecular weight: Translated: 50195; Mature: 50064

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADW
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CADWPAALRQRLNQRQPALKPVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYS
HCCCHHHHHHHHHHCCCHHHHHHHCCHHHEECCCCCCCHHHHHHHHHHHHHHHHEEEEEE
LEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLLTVMAAGKQVVVSRGELVEIG
ECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEEC
GAFRIPDVMRQAGCDLVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
CCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQ
HHHHHCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCC
AGIILGKKQWIERLQQHPLKRALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEHHCCH
SEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPVDRLPSWALTFTPKDGRGSTL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCHH
EALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
SAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADW
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CADWPAALRQRLNQRQPALKPVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYS
HCCCHHHHHHHHHHCCCHHHHHHHCCHHHEECCCCCCCHHHHHHHHHHHHHHHHEEEEEE
LEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLLTVMAAGKQVVVSRGELVEIG
ECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEEC
GAFRIPDVMRQAGCDLVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
CCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQ
HHHHHCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCC
AGIILGKKQWIERLQQHPLKRALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEHHCCH
SEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPVDRLPSWALTFTPKDGRGSTL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCHH
EALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA