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The map label for this gene is dgt

Identifier: 51595098

GI number: 51595098

Start: 898611

End: 900131

Strand: Direct

Name: dgt

Synonym: YPTB0748

Alternate gene names: 51595098

Gene position: 898611-900131 (Clockwise)

Preceding gene: 51595094

Following gene: 51595099

Centisome position: 18.94

GC content: 43.2

Gene sequence:

>1521_bases
ATGTCCGGGATCGACTTTAAGCAGAAAATAAGTTTCCAGCGGCCTTTTAGTAAGCCCAGTTCAGCAGAAGATGAATATGA
AATAACAAGGGTATTTGAAAGTGATCGTGGGCGGATTGTTAACTCTGCTGCTATCCGGCGTCTGCAACAAAAAACGCAAG
TATTCCCGCTGGAACGCAATGCCGCCGTTCGTAGCCGATTAACCCATTCGTTGGAAGTGCAACAAGTCGGGCGTTATATC
GCGAAAGAGATCCTGAACCGCTTTAAACAGGATAAAAAAATCACTGCCTACGGTTTGGATAAACTACTCGACCCTTTTGA
AAGTATTGTTGAAATGGCCTGCCTGATGCATGACATTGGTAACCCGCCATTTGGTCATTTCGGTGAGTCAGCGATCAATG
ATTGGTTTACAAAACGGATGGACCCTAACGGCGGCAGCGGTTCTGAACCACAAAGCACAGATCAATGTCAGGTAGAGGTG
CTGAAGCTATGTGAGGGAGAAACCGAACTTAATATTCTGCGCAGTAAAATTCGTCATGACCTTAGCCAGTTTGAGGGCAA
CGCTCAGGCTATTCGTTTGGTTCACAGTTTATTAAAACTGAATCTGACCTATGCTCAGGTGGGTTGTATTCTTAAATATA
CTAAGCCCGCTTATTGGTCAGCCCCTATTCCAGCGTCCCATAACTATTTGATGAAAAAACCCGGCTTCTATCTGGCAGAG
GAAAATTACGTCAAAGAACTGCGTCGCGAACTCAATATGGAAGAGTTTGACCGTTTTCCACTGACTTATATTATGGAGGC
CGCCGATGATATTTCTTACTGTATAGCCGATTTAGAAGATGCAGTAGAAAAAAATATTTTCAGTGTCGAACAACTCTATG
ATCATATGAGCCAAGAGTGGGGGGCCGTTACACCGGGGGATCTGTTTGATAAAGTCGTGGGTGCCGCTTTTCGTCAATTA
GGCCGTGAGCAAGGCCGGCGTAGCTCAGAAGATCAATTCTTTATGTATCTACGGGTAAATACTGTGGGGAAATTAGTCCC
TCATGCGGCACAACGCTTTATTGAAAATCTACCGGCTGTTTTTTCAGGCTCTTTTAACCAGGCATTGTTAGAAGATTCCA
GTGCCGCTTGTAAGTTATTGCAAATTTTCAAACGTGTCGCAGTAAAACATGTATTTAACCACCCAGAAGTTGAACAGCTT
GAATTACAAGGGTATAGAGTCATCAGTGGGCTGCTTGATATTTATAGCCCGTTATTAGCAATGCCAGAGACCGCCTTTAC
ACAATTAGTTGCAGATGACCGCCACCGTAAGTATCCAATTGAAACACGGTTATTTCATAAATTATCGATTAAACATCGGT
TAGCTTATGCTGAATCTGCAGAAAGAATCCGTAATTTACCGTCCGAACAATATGAGATATATGAATATTATTATCGTGCG
CGGTTAATTCAGGATTATATCAGTGGGATGACCGATCTTTATGCTTATGATGAATACCGGCGTTTAATGGCTGCGGAATA
G

Upstream 100 bases:

>100_bases
TTTTGAATACAACATGATTTTGAATACAACATGATTTTGAATGCAGGATGGTTTTGAATAATTCAGGGTGGTTTTGGAAT
ATAGATAACCAGGGGGAAAT

Downstream 100 bases:

>100_bases
TATGCAAAAATTTGAATTGTCCGTTTAATTAATTATAGTTTTGTAAAGACGGACAATATTTTTTACTCTTAATTTTCTTG
GCCCTATGAACTTCATCCCC

Product: deoxyguanosinetriphosphate triphosphohydrolase

Products: NA

Alternate protein names: dGTP triphosphohydrolase; dGTPase

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQVGRYI
AKEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIGNPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVEV
LKLCEGETELNILRSKIRHDLSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAE
ENYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEWGAVTPGDLFDKVVGAAFRQL
GREQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAVFSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQL
ELQGYRVISGLLDIYSPLLAMPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRA
RLIQDYISGMTDLYAYDEYRRLMAAE

Sequences:

>Translated_506_residues
MSGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQVGRYI
AKEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIGNPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVEV
LKLCEGETELNILRSKIRHDLSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAE
ENYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEWGAVTPGDLFDKVVGAAFRQL
GREQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAVFSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQL
ELQGYRVISGLLDIYSPLLAMPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRA
RLIQDYISGMTDLYAYDEYRRLMAAE
>Mature_505_residues
SGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQVGRYIA
KEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIGNPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVEVL
KLCEGETELNILRSKIRHDLSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAEE
NYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEWGAVTPGDLFDKVVGAAFRQLG
REQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAVFSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQLE
LQGYRVISGLLDIYSPLLAMPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRAR
LIQDYISGMTDLYAYDEYRRLMAAE

Specific function: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs

COG id: COG0232

COG function: function code F; dGTP triphosphohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dGTPase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1786355, Length=508, Percent_Identity=64.9606299212598, Blast_Score=700, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DGTP_YERP3 (A7FM03)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402281.1
- ProteinModelPortal:   A7FM03
- SMR:   A7FM03
- STRING:   A7FM03
- GeneID:   5387009
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3324
- eggNOG:   COG0232
- HOGENOM:   HBG470926
- OMA:   LVEMACL
- ProtClustDB:   PRK04926
- BioCyc:   YPSE349747:YPSIP31758_3324-MONOMER
- HAMAP:   MF_00030
- InterPro:   IPR006261
- InterPro:   IPR020779
- InterPro:   IPR003607
- SMART:   SM00471
- TIGRFAMs:   TIGR01353

Pfam domain/function: NA

EC number: =3.1.5.1

Molecular weight: Translated: 58438; Mature: 58307

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERN
CCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCH
AAVRSRLTHSLEVQQVGRYIAKEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVEVLKLCEGETELNILRSKIRHD
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEECC
ENYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEW
HHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAVTPGDLFDKVVGAAFRQLGREQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCHH
FSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQLELQGYRVISGLLDIYSPLLA
HCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRA
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RLIQDYISGMTDLYAYDEYRRLMAAE
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERN
CCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCH
AAVRSRLTHSLEVQQVGRYIAKEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVEVLKLCEGETELNILRSKIRHD
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEECC
ENYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEW
HHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAVTPGDLFDKVVGAAFRQLGREQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCHH
FSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQLELQGYRVISGLLDIYSPLLA
HCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRA
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RLIQDYISGMTDLYAYDEYRRLMAAE
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA