Click here to switch to the map view.

The map label for this gene is moaC [H]

Identifier: 50841982

GI number: 50841982

Start: 548485

End: 548970

Strand: Reverse

Name: moaC [H]

Synonym: PPA0498

Alternate gene names: 50841982

Gene position: 548970-548485 (Counterclockwise)

Preceding gene: 50841983

Following gene: 50841981

Centisome position: 21.44

GC content: 65.02

Gene sequence:

>486_bases
ATGACCTCACACCCATTCACCCACCTGCGTGGTAACGGATCGGCTCACATGGTCGACGTCACGACAAAGACACCCACGGT
GCGCGTGGCGACGGCGGAATGCTGCGTGGTGTGCTCCGAGCCGATCATGACTGCCCTGCGCGACGAATCGGTCCCCAAAG
GGGACGTCCTCGCCGTGGCCCGCATCGCAGGTATCCAGGCCACCAAGCACACTCCAGACCTCATCCCCCTGGCGCACCGC
ATCGGTGTGCACGGGGCAGAAGTGGACCTGTGGCTGGAGCCTGACCGGGTGAGGATCCGTGCCACAACCCGTACCACCGA
TCGCACCGGAGTGGAGATGGAAGCGCTCACCGCTGTGACGGTGGCTGCCCTCACCGTCGCCGACATGGTCAAGGGAGTCG
ATCGCGGCTTCGCCATCGAGCACGCGGTGATCACTCACAAAGCCGGTGGACGCAGCGGCGAGTGGACCAGGAGCGACGAC
CAATGA

Upstream 100 bases:

>100_bases
AGTCTGCCTCTGGTAGAGGGCCTGGCGGTGGCGGGTCCCGGAATCGATCACGTGGACTCCGGCGACGAGTTGAGCATCCT
ACTGACGGGAGGAGTTACAC

Downstream 100 bases:

>100_bases
GCCCCGAGCAGGTGACAGAACCCGTCACCGGTTCTCTCGACGACGAGCTGGACCAGTTCGCGGCAGTGTTCACCATCCTA
GGTTCTTTGCACTATCAAGT

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTSHPFTHLRGNGSAHMVDVTTKTPTVRVATAECCVVCSEPIMTALRDESVPKGDVLAVARIAGIQATKHTPDLIPLAHR
IGVHGAEVDLWLEPDRVRIRATTRTTDRTGVEMEALTAVTVAALTVADMVKGVDRGFAIEHAVITHKAGGRSGEWTRSDD
Q

Sequences:

>Translated_161_residues
MTSHPFTHLRGNGSAHMVDVTTKTPTVRVATAECCVVCSEPIMTALRDESVPKGDVLAVARIAGIQATKHTPDLIPLAHR
IGVHGAEVDLWLEPDRVRIRATTRTTDRTGVEMEALTAVTVAALTVADMVKGVDRGFAIEHAVITHKAGGRSGEWTRSDD
Q
>Mature_160_residues
TSHPFTHLRGNGSAHMVDVTTKTPTVRVATAECCVVCSEPIMTALRDESVPKGDVLAVARIAGIQATKHTPDLIPLAHRI
GVHGAEVDLWLEPDRVRIRATTRTTDRTGVEMEALTAVTVAALTVADMVKGVDRGFAIEHAVITHKAGGRSGEWTRSDDQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=48.7341772151899, Blast_Score=129, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI32566331, Length=161, Percent_Identity=35.4037267080745, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=45.5696202531646, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=45.578231292517, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17284; Mature: 17153

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHPFTHLRGNGSAHMVDVTTKTPTVRVATAECCVVCSEPIMTALRDESVPKGDVLAVA
CCCCCCCEEECCCCEEEEEEECCCCEEEEEEHHEEEEECCHHHHHHHCCCCCCCCEEEEE
RIAGIQATKHTPDLIPLAHRIGVHGAEVDLWLEPDRVRIRATTRTTDRTGVEMEALTAVT
HHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHH
VAALTVADMVKGVDRGFAIEHAVITHKAGGRSGEWTRSDDQ
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSHPFTHLRGNGSAHMVDVTTKTPTVRVATAECCVVCSEPIMTALRDESVPKGDVLAVA
CCCCCCEEECCCCEEEEEEECCCCEEEEEEHHEEEEECCHHHHHHHCCCCCCCCEEEEE
RIAGIQATKHTPDLIPLAHRIGVHGAEVDLWLEPDRVRIRATTRTTDRTGVEMEALTAVT
HHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHH
VAALTVADMVKGVDRGFAIEHAVITHKAGGRSGEWTRSDDQ
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12692562; 11572948 [H]