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The map label for this gene is 50841972

Identifier: 50841972

GI number: 50841972

Start: 540108

End: 541505

Strand: Direct

Name: 50841972

Synonym: PPA0489

Alternate gene names: NA

Gene position: 540108-541505 (Clockwise)

Preceding gene: 50841971

Following gene: 50841973

Centisome position: 21.1

GC content: 57.73

Gene sequence:

>1398_bases
ATGAGTGAAGAAGGACTTGCGGCTGCACGCCAGAAGATGACCGAGGCAGGTGTCGATCCTGTCGCCATCGAGGTCTTCAC
TTCCTACTACCACCAGCTCGAGACCGGCGATACCGGACTCATCCGCGAGGACACCATCTCCCCGCTCACGAATCCGCCAA
TGCTCGACGACGTTGAGGTCAGCGAGGAGCAGGCTGCTGAGGCCCTCGACAAGACCGTCATCATCAAGCTCAATGGCGGG
CTCGGAACCTCGATGGGCCTCGACCGAGCTAAGTCGCTGCTCGAAGTTCGTGACGGCAAGTCCTTCCTCGACATCATCGC
TACCCAGGTGCTCTCGGCTCGCAAGACTTTCGGCGCTCGATTGCCGCTGATGTTCATGAATTCCTTCAATACCCGCGAGG
ACACCCTCAAGGCCCTCGAGAAATATCCAGAGTTGGCTGTCGACGGCCTAGAGCTCGACTTCCTGCAGGATCAGGAGCCT
AAGCTCGACGCTGAGACCCTCGCCCCGGTTGAGTGGCCGAAGGACTCCTCCCTCGAGTGGTGTCCTCCGGGTCACGGCGA
CCTCTACACCGCTCTGCTTGGATCCGGCGTCCTCGACCATCTGCTCGAGGCTGGATACCAATACGCCTCGGTATCCAATG
GTGACAATCTTGGTGCCGTTCCGGACGGTCGTCTCGCCGGCTGGTTTGCGGCGTCGGGTGCTCCCTACGCTGCCGAGTTG
TGCCGTCGCACTATTAACGACAAGAAGGGTGGCCACCTGGCCATTCGTAAGTCTGATGATCAGCTCATCCTGCGCGATAC
GGCACAGACAGCAGAAGAGGAAATGGATTACTTCACCGACGAGCATCGTCACCCCTTCTTTCACACCAACAATCTGTGGT
TTGACCTTGAAGCCCTCAAGAAGGTGCTGGACGAGCGACACGGCGTGATGGGCCTGCAAATTATTCGCAACGAGAAGACG
GTCGACCCGAAGGATTCCTCGTCGACTCCTGTCATCCAGATTGAGTCCGCTATGGGGGGCGCTATCGAGGTCTTTGAAGG
CGCTACCTGTATCTGTGTTGATCGGTCCCGGTTCTTGCCGGTCAAAACGACCAACGAGCTGCTGCTGCTTCGGTCTGATG
TTTATGACCTCGACGATTCGGACCACCTCGTCAAGACCACCGACATGACCTGCGCAGTCGATCTTGACAAGGATTTTTAT
AAAAAGATTAGTGATTTCGACGATCGCATCCCTGAGCCGCCATCGCTGCGCCGCGCCACCTCGCTGAAGGTCAAAGGAGA
CTGGACCTTTGGTTCGGAGGTTGTCGTTGCGGGGGATGTTTCGCTGGATACTGAGAAGCCTCAGACGATTCCGGACGGGA
CCGTGCTCACTGGCGAAGTCCTTGGCGCGAAAAAGTGA

Upstream 100 bases:

>100_bases
TGGCAACCTGGCGCACCGACGACGTAGTGGCGTGCTCTGGCCTGTCAGTGGGCTCTTCTCGGTACAATGACGGCGTTCGT
TAACACGCAAGGGGGCCAGG

Downstream 100 bases:

>100_bases
CACCGGATCGACAATGCTGGGAGGCGGTGGCCGCGGTCTTGACCGGACAGCGACTTACCGCTCCTGACAACCCAGGATGG
CAGGCCGTCGACGTCGTGGA

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: diphosphate; UDP-glucose

Alternate protein names: UDP-Glucose Pyrophosphorylase; UTP-Glucose-1-Phosphate Uridyltransferase; Nucleotide Glucose-1-Phosphate Uridylyl Transferase; Glucose-1-Phosphate Uridylyltransferase; Molybdenum Cofactor Synthesis Domain Protein

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSEEGLAAARQKMTEAGVDPVAIEVFTSYYHQLETGDTGLIREDTISPLTNPPMLDDVEVSEEQAAEALDKTVIIKLNGG
LGTSMGLDRAKSLLEVRDGKSFLDIIATQVLSARKTFGARLPLMFMNSFNTREDTLKALEKYPELAVDGLELDFLQDQEP
KLDAETLAPVEWPKDSSLEWCPPGHGDLYTALLGSGVLDHLLEAGYQYASVSNGDNLGAVPDGRLAGWFAASGAPYAAEL
CRRTINDKKGGHLAIRKSDDQLILRDTAQTAEEEMDYFTDEHRHPFFHTNNLWFDLEALKKVLDERHGVMGLQIIRNEKT
VDPKDSSSTPVIQIESAMGGAIEVFEGATCICVDRSRFLPVKTTNELLLLRSDVYDLDDSDHLVKTTDMTCAVDLDKDFY
KKISDFDDRIPEPPSLRRATSLKVKGDWTFGSEVVVAGDVSLDTEKPQTIPDGTVLTGEVLGAKK

Sequences:

>Translated_465_residues
MSEEGLAAARQKMTEAGVDPVAIEVFTSYYHQLETGDTGLIREDTISPLTNPPMLDDVEVSEEQAAEALDKTVIIKLNGG
LGTSMGLDRAKSLLEVRDGKSFLDIIATQVLSARKTFGARLPLMFMNSFNTREDTLKALEKYPELAVDGLELDFLQDQEP
KLDAETLAPVEWPKDSSLEWCPPGHGDLYTALLGSGVLDHLLEAGYQYASVSNGDNLGAVPDGRLAGWFAASGAPYAAEL
CRRTINDKKGGHLAIRKSDDQLILRDTAQTAEEEMDYFTDEHRHPFFHTNNLWFDLEALKKVLDERHGVMGLQIIRNEKT
VDPKDSSSTPVIQIESAMGGAIEVFEGATCICVDRSRFLPVKTTNELLLLRSDVYDLDDSDHLVKTTDMTCAVDLDKDFY
KKISDFDDRIPEPPSLRRATSLKVKGDWTFGSEVVVAGDVSLDTEKPQTIPDGTVLTGEVLGAKK
>Mature_464_residues
SEEGLAAARQKMTEAGVDPVAIEVFTSYYHQLETGDTGLIREDTISPLTNPPMLDDVEVSEEQAAEALDKTVIIKLNGGL
GTSMGLDRAKSLLEVRDGKSFLDIIATQVLSARKTFGARLPLMFMNSFNTREDTLKALEKYPELAVDGLELDFLQDQEPK
LDAETLAPVEWPKDSSLEWCPPGHGDLYTALLGSGVLDHLLEAGYQYASVSNGDNLGAVPDGRLAGWFAASGAPYAAELC
RRTINDKKGGHLAIRKSDDQLILRDTAQTAEEEMDYFTDEHRHPFFHTNNLWFDLEALKKVLDERHGVMGLQIIRNEKTV
DPKDSSSTPVIQIESAMGGAIEVFEGATCICVDRSRFLPVKTTNELLLLRSDVYDLDDSDHLVKTTDMTCAVDLDKDFYK
KISDFDDRIPEPPSLRRATSLKVKGDWTFGSEVVVAGDVSLDTEKPQTIPDGTVLTGEVLGAKK

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI48255966, Length=413, Percent_Identity=36.319612590799, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI48255968, Length=413, Percent_Identity=36.319612590799, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71988370, Length=417, Percent_Identity=37.1702637889688, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI71988365, Length=417, Percent_Identity=37.1702637889688, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17554114, Length=417, Percent_Identity=37.1702637889688, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17554112, Length=417, Percent_Identity=37.1702637889688, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17554108, Length=417, Percent_Identity=37.1702637889688, Blast_Score=241, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI25151022, Length=414, Percent_Identity=36.4734299516908, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17554110, Length=396, Percent_Identity=36.3636363636364, Blast_Score=221, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6322815, Length=419, Percent_Identity=36.7541766109785, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321775, Length=410, Percent_Identity=27.8048780487805, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281365931, Length=416, Percent_Identity=37.9807692307692, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI281365929, Length=416, Percent_Identity=37.9807692307692, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI62484452, Length=417, Percent_Identity=37.410071942446, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI62484278, Length=417, Percent_Identity=37.410071942446, Blast_Score=238, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.9

Molecular weight: Translated: 51189; Mature: 51058

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEGLAAARQKMTEAGVDPVAIEVFTSYYHQLETGDTGLIREDTISPLTNPPMLDDVEV
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCC
SEEQAAEALDKTVIIKLNGGLGTSMGLDRAKSLLEVRDGKSFLDIIATQVLSARKTFGAR
CHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
LPLMFMNSFNTREDTLKALEKYPELAVDGLELDFLQDQEPKLDAETLAPVEWPKDSSLEW
CCHHHHCCCCCHHHHHHHHHHCHHHEECCCEEEECCCCCCCCCHHHCCCCCCCCCCCCCC
CPPGHGDLYTALLGSGVLDHLLEAGYQYASVSNGDNLGAVPDGRLAGWFAASGAPYAAEL
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHH
CRRTINDKKGGHLAIRKSDDQLILRDTAQTAEEEMDYFTDEHRHPFFHTNNLWFDLEALK
HHHHHCCCCCCEEEEEECCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCEEEEHHHHH
KVLDERHGVMGLQIIRNEKTVDPKDSSSTPVIQIESAMGGAIEVFEGATCICVDRSRFLP
HHHHHHCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEECCCEEEEECCCCEEE
VKTTNELLLLRSDVYDLDDSDHLVKTTDMTCAVDLDKDFYKKISDFDDRIPEPPSLRRAT
ECCCCCEEEEECCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCE
SLKVKGDWTFGSEVVVAGDVSLDTEKPQTIPDGTVLTGEVLGAKK
EEEEEECCCCCCCEEEEECCEECCCCCCCCCCCCEEEEHHCCCCC
>Mature Secondary Structure 
SEEGLAAARQKMTEAGVDPVAIEVFTSYYHQLETGDTGLIREDTISPLTNPPMLDDVEV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCC
SEEQAAEALDKTVIIKLNGGLGTSMGLDRAKSLLEVRDGKSFLDIIATQVLSARKTFGAR
CHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
LPLMFMNSFNTREDTLKALEKYPELAVDGLELDFLQDQEPKLDAETLAPVEWPKDSSLEW
CCHHHHCCCCCHHHHHHHHHHCHHHEECCCEEEECCCCCCCCCHHHCCCCCCCCCCCCCC
CPPGHGDLYTALLGSGVLDHLLEAGYQYASVSNGDNLGAVPDGRLAGWFAASGAPYAAEL
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHH
CRRTINDKKGGHLAIRKSDDQLILRDTAQTAEEEMDYFTDEHRHPFFHTNNLWFDLEALK
HHHHHCCCCCCEEEEEECCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCEEEEHHHHH
KVLDERHGVMGLQIIRNEKTVDPKDSSSTPVIQIESAMGGAIEVFEGATCICVDRSRFLP
HHHHHHCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEECCCEEEEECCCCEEE
VKTTNELLLLRSDVYDLDDSDHLVKTTDMTCAVDLDKDFYKKISDFDDRIPEPPSLRRAT
ECCCCCEEEEECCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCE
SLKVKGDWTFGSEVVVAGDVSLDTEKPQTIPDGTVLTGEVLGAKK
EEEEEECCCCCCCEEEEECCEECCCCCCCCCCCCEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; alpha-D-glucose 1-phosphate

Specific reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA