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The map label for this gene is 50841956

Identifier: 50841956

GI number: 50841956

Start: 521933

End: 524017

Strand: Reverse

Name: 50841956

Synonym: PPA0473

Alternate gene names: NA

Gene position: 524017-521933 (Counterclockwise)

Preceding gene: 50841957

Following gene: 50841955

Centisome position: 20.47

GC content: 61.29

Gene sequence:

>2085_bases
ATGCTCCCGCATCCACCTTTCGCGGGTCGACGTCCACGTATTCATGATAGTGCGCATGCCCACGGCCATACCCACAAGCT
CAGACAGTATGCGCTCAACAACCAATCACCCGACCGGCTACTGAGCACACAACCCGTCCACGCACACTGCGGCGATCTCC
CTGCGGCGCGAGAGGGCTTTCTGCGCTGTCATCATGGCCCCAGCGCAGCCAGACCATCGCATCTCGGAACGCGGCTGACG
TGGAGCTGCTGGTTCCCCCGCCTAGCTGTGGCTATGCGGCTCGCAAGCGTTCCCTCTGCCATCTGCGGTGGCAACAGGAT
CCTCGCCGCGCATCATTGCCACAACCGCCCGCGGGCTGCGACACCGACGCACTCAACCCGAACCTCGCCGGGAACAAACG
CACGCTGTGGGGCGATACTTGGAGTGATGACTTCTGTACCCGGCCCACTCATTGTCCAGTCCGACCACACTCTCCTGCTG
GAGGTAGACCACCCCCAGGCAGACGAGTGTCGCCACGCTATAGCCCCATTCGCGGAACTAGAACGCGCCCCTGAACACAT
CCACACCTACCGGCTCACCCCGCTGGGACTGTGGAATGCCATGGCTGCCGGCCACGACGCAGAGCAAGTCGTCGACATCC
TCATGAGGTATTCGCGCTACCCGGTAGCCTCCGGCCTGCTCATCGATGTCACCGAGACGATGTCAAGGTATGGCAGGTTG
CGCATTGAGAAGCACCCCACCCATGGGCTGGTATTGGTGTCGACTGAACGAGCCATACTCACCGAGGTGTTGCGTTCCAA
GTCAGTGCGCGGTCTTGTCGGTAATCAAATCGATGATGAGACGGCTGTGGTCCATCCTTCGCAGCGCGGCACCCTCAAAC
AGGCGCTGCTCAAGCTGGGGTGGCCGGCTGAAGACCTCGCCGGTTACGTCGACGGCGAGCACCACGACATCGACCTTGAC
GAGGATGGTTGGAGCCTGCGCCCCTACCAGAAAGTAGCGGCGCAGTCTTTCTGGGACGGCGGATCTGGAGTCGTTGTACT
GCCCTGCGGCGCTGGCAAAACGGTCGTCGGGGCCACCGCTATGAGCCTCGCCCGCTGCACCACTCTGATCCTCGTTACCA
ACACCGTTTCAGCACGGCAGTGGAAAGAGGAACTCGTTCGTCGCACCTCCCTCGCCCCCGACGACATCGGTGAATACTCC
GGGTCGCGCAAACCAGTGCGCCCGGTAACAATCGCCACCTATCAGGTCATCACCACCAAACGTCACGGAGTGCACCCACA
CCTAGAACTCTTCGAAGCCCGCGACTGGGGCCTAGTGATATATGACGAGGTACACCTGCTGCCGGCCCCGGTCTTCCGAA
TGACGGCTGACCTGCAAGCGCGTCGTCGTCTCGGCCTGACAGCCACCCTAGTGCGTGAGGACGGACACGAGGACGATGTC
TTCACCCTCATCGGCCCGAAACGCTACGACGCTCCGTGGAAGGAAATCGAAGCCCAAGGATGGATCGCACCTGCTGATTG
CGTCGAGGTGCGGGTGAGCTTGTCGGAGTCTGACCGGATGGCCTGCGCGATGGCCGAGCCTGACGTCCGCTACCGGATGG
CCGCAACCCTCCCCATTAAAAACAAGGTCGTGAGAGACCTGGTCGAGCGTCATCGTGGACAGCCCACCCTTGTCATCGGC
CAATACGTTGACCAGTTGGAGGAGCTGGCCGCGGAATTGAAGTGCCCGATTATCACCGGTTCAACGACGCCGACTCGCCG
TCAGGAGATCTACCAGGACTTCCGGGAGGGGCAGATCGACCTGCTCGTAGTCTCTAAGGTCGCCAACTTCTCCATTGACC
TACCAAGCGCGGAGGTCGCCATCCAGGTCTCGGGAGCATTTGGATCGCGTCAAGAAGAGGCCCAGCGTTTGGGCCGTCTA
CTGCGTCCCAAAGAGGGCCTGGTGGCCCGTTTCTATGCGGTCGTCTCGCGCGATACCGTTGATACAGACTTTGCCAGCCA
TCGTCAGCGATTCCTGGCCGAGCAGGGATACTCGTACCGCATCATTGATGCAGACGATCTGGACGCATTGGACCGAACGG
CGTGA

Upstream 100 bases:

>100_bases
AGTGGCGACGCTTCCCGAAGAGGCCGCGCCGGTCACCGTGGTGAACACGGTTACGGGACGTCCTTGAAATTGGATATATT
CCCAGTATGCATGAGCACTC

Downstream 100 bases:

>100_bases
GAATGGACGTGAACGCACCGGGTCCACGAACAGGAGGACATGCTTGTCTGGGAAGGCGCTAATCGCCAGACGTACAGCGT
TAGGGGGCTTGCTCGTCGCT

Product: superfamily II DNA/RNA helicase

Products: NA

Alternate protein names: DNA Repair Helicase; Type III Restriction Res Subunit; Helicase Domain-Containing Protein; Helicase Domain Protein; ATP-Dependent DNA Helicase; DNA Repair Helicase RAD; DNA Repair Helicase Rad; Type III Restriction Res Subunit Family; Helicase; DNA Repair Protein Rad; Superfamily II DNA/RNA Helicase; DNA/RNA Helicase; DNA Repair Protein; DNA Repair Protein RAD; DNA Helicase; DNA/RNA Helicase Superfamily II; Helicase-Like Protein; Helicase Protein; ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily II; DNA/RNA Repair Helicase; Helicase DNA Repair; Helicase DNA Repair Rad; XPB/RAD25-Related Helicase; DEAD/DEAH Box Helicase-Like; DNA-Helicase; Nucleic Acid ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily Protein II; DEAD/DEAH Box Helicase; Helicase ATP-Dependent; DNA Or RNA Helicase; RAD25-Type DNA Repair Helicase; DNA Repair Related Protein; Restriction Endonuclease Family Protein; Helicase ATP-Dependent Intein-Containing

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MLPHPPFAGRRPRIHDSAHAHGHTHKLRQYALNNQSPDRLLSTQPVHAHCGDLPAAREGFLRCHHGPSAARPSHLGTRLT
WSCWFPRLAVAMRLASVPSAICGGNRILAAHHCHNRPRAATPTHSTRTSPGTNARCGAILGVMTSVPGPLIVQSDHTLLL
EVDHPQADECRHAIAPFAELERAPEHIHTYRLTPLGLWNAMAAGHDAEQVVDILMRYSRYPVASGLLIDVTETMSRYGRL
RIEKHPTHGLVLVSTERAILTEVLRSKSVRGLVGNQIDDETAVVHPSQRGTLKQALLKLGWPAEDLAGYVDGEHHDIDLD
EDGWSLRPYQKVAAQSFWDGGSGVVVLPCGAGKTVVGATAMSLARCTTLILVTNTVSARQWKEELVRRTSLAPDDIGEYS
GSRKPVRPVTIATYQVITTKRHGVHPHLELFEARDWGLVIYDEVHLLPAPVFRMTADLQARRRLGLTATLVREDGHEDDV
FTLIGPKRYDAPWKEIEAQGWIAPADCVEVRVSLSESDRMACAMAEPDVRYRMAATLPIKNKVVRDLVERHRGQPTLVIG
QYVDQLEELAAELKCPIITGSTTPTRRQEIYQDFREGQIDLLVVSKVANFSIDLPSAEVAIQVSGAFGSRQEEAQRLGRL
LRPKEGLVARFYAVVSRDTVDTDFASHRQRFLAEQGYSYRIIDADDLDALDRTA

Sequences:

>Translated_694_residues
MLPHPPFAGRRPRIHDSAHAHGHTHKLRQYALNNQSPDRLLSTQPVHAHCGDLPAAREGFLRCHHGPSAARPSHLGTRLT
WSCWFPRLAVAMRLASVPSAICGGNRILAAHHCHNRPRAATPTHSTRTSPGTNARCGAILGVMTSVPGPLIVQSDHTLLL
EVDHPQADECRHAIAPFAELERAPEHIHTYRLTPLGLWNAMAAGHDAEQVVDILMRYSRYPVASGLLIDVTETMSRYGRL
RIEKHPTHGLVLVSTERAILTEVLRSKSVRGLVGNQIDDETAVVHPSQRGTLKQALLKLGWPAEDLAGYVDGEHHDIDLD
EDGWSLRPYQKVAAQSFWDGGSGVVVLPCGAGKTVVGATAMSLARCTTLILVTNTVSARQWKEELVRRTSLAPDDIGEYS
GSRKPVRPVTIATYQVITTKRHGVHPHLELFEARDWGLVIYDEVHLLPAPVFRMTADLQARRRLGLTATLVREDGHEDDV
FTLIGPKRYDAPWKEIEAQGWIAPADCVEVRVSLSESDRMACAMAEPDVRYRMAATLPIKNKVVRDLVERHRGQPTLVIG
QYVDQLEELAAELKCPIITGSTTPTRRQEIYQDFREGQIDLLVVSKVANFSIDLPSAEVAIQVSGAFGSRQEEAQRLGRL
LRPKEGLVARFYAVVSRDTVDTDFASHRQRFLAEQGYSYRIIDADDLDALDRTA
>Mature_694_residues
MLPHPPFAGRRPRIHDSAHAHGHTHKLRQYALNNQSPDRLLSTQPVHAHCGDLPAAREGFLRCHHGPSAARPSHLGTRLT
WSCWFPRLAVAMRLASVPSAICGGNRILAAHHCHNRPRAATPTHSTRTSPGTNARCGAILGVMTSVPGPLIVQSDHTLLL
EVDHPQADECRHAIAPFAELERAPEHIHTYRLTPLGLWNAMAAGHDAEQVVDILMRYSRYPVASGLLIDVTETMSRYGRL
RIEKHPTHGLVLVSTERAILTEVLRSKSVRGLVGNQIDDETAVVHPSQRGTLKQALLKLGWPAEDLAGYVDGEHHDIDLD
EDGWSLRPYQKVAAQSFWDGGSGVVVLPCGAGKTVVGATAMSLARCTTLILVTNTVSARQWKEELVRRTSLAPDDIGEYS
GSRKPVRPVTIATYQVITTKRHGVHPHLELFEARDWGLVIYDEVHLLPAPVFRMTADLQARRRLGLTATLVREDGHEDDV
FTLIGPKRYDAPWKEIEAQGWIAPADCVEVRVSLSESDRMACAMAEPDVRYRMAATLPIKNKVVRDLVERHRGQPTLVIG
QYVDQLEELAAELKCPIITGSTTPTRRQEIYQDFREGQIDLLVVSKVANFSIDLPSAEVAIQVSGAFGSRQEEAQRLGRL
LRPKEGLVARFYAVVSRDTVDTDFASHRQRFLAEQGYSYRIIDADDLDALDRTA

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557563, Length=413, Percent_Identity=38.2566585956416, Blast_Score=248, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17556358, Length=384, Percent_Identity=37.5, Blast_Score=240, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322048, Length=392, Percent_Identity=36.4795918367347, Blast_Score=255, Evalue=1e-68,
Organism=Drosophila melanogaster, GI221331068, Length=392, Percent_Identity=37.2448979591837, Blast_Score=243, Evalue=5e-64,
Organism=Drosophila melanogaster, GI24662247, Length=392, Percent_Identity=37.2448979591837, Blast_Score=243, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 76930; Mature: 76930

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPHPPFAGRRPRIHDSAHAHGHTHKLRQYALNNQSPDRLLSTQPVHAHCGDLPAAREGF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCHHCCCCCCHHHHHH
LRCHHGPSAARPSHLGTRLTWSCWFPRLAVAMRLASVPSAICGGNRILAAHHCHNRPRAA
EEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCC
TPTHSTRTSPGTNARCGAILGVMTSVPGPLIVQSDHTLLLEVDHPQADECRHAIAPFAEL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEECCCCHHHHHHHHCCHHHH
ERAPEHIHTYRLTPLGLWNAMAAGHDAEQVVDILMRYSRYPVASGLLIDVTETMSRYGRL
HHCHHHHHEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCE
RIEKHPTHGLVLVSTERAILTEVLRSKSVRGLVGNQIDDETAVVHPSQRGTLKQALLKLG
EEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCC
WPAEDLAGYVDGEHHDIDLDEDGWSLRPYQKVAAQSFWDGGSGVVVLPCGAGKTVVGATA
CCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
MSLARCTTLILVTNTVSARQWKEELVRRTSLAPDDIGEYSGSRKPVRPVTIATYQVITTK
HHHHHHEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEEEEEECC
RHGVHPHLELFEARDWGLVIYDEVHLLPAPVFRMTADLQARRRLGLTATLVREDGHEDDV
CCCCCCCHHHEECCCCCEEEEECCEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
FTLIGPKRYDAPWKEIEAQGWIAPADCVEVRVSLSESDRMACAMAEPDVRYRMAATLPIK
EEEECCCCCCCCHHHHCCCCCCCCHHHEEEEEECCCCCCEEEEECCCCCEEEEEEECCHH
NKVVRDLVERHRGQPTLVIGQYVDQLEELAAELKCPIITGSTTPTRRQEIYQDFREGQID
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEE
LLVVSKVANFSIDLPSAEVAIQVSGAFGSRQEEAQRLGRLLRPKEGLVARFYAVVSRDTV
EEEEEECCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
DTDFASHRQRFLAEQGYSYRIIDADDLDALDRTA
CHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCC
>Mature Secondary Structure
MLPHPPFAGRRPRIHDSAHAHGHTHKLRQYALNNQSPDRLLSTQPVHAHCGDLPAAREGF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCHHCCCCCCHHHHHH
LRCHHGPSAARPSHLGTRLTWSCWFPRLAVAMRLASVPSAICGGNRILAAHHCHNRPRAA
EEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCC
TPTHSTRTSPGTNARCGAILGVMTSVPGPLIVQSDHTLLLEVDHPQADECRHAIAPFAEL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEECCCCHHHHHHHHCCHHHH
ERAPEHIHTYRLTPLGLWNAMAAGHDAEQVVDILMRYSRYPVASGLLIDVTETMSRYGRL
HHCHHHHHEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCE
RIEKHPTHGLVLVSTERAILTEVLRSKSVRGLVGNQIDDETAVVHPSQRGTLKQALLKLG
EEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCC
WPAEDLAGYVDGEHHDIDLDEDGWSLRPYQKVAAQSFWDGGSGVVVLPCGAGKTVVGATA
CCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
MSLARCTTLILVTNTVSARQWKEELVRRTSLAPDDIGEYSGSRKPVRPVTIATYQVITTK
HHHHHHEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEEEEEECC
RHGVHPHLELFEARDWGLVIYDEVHLLPAPVFRMTADLQARRRLGLTATLVREDGHEDDV
CCCCCCCHHHEECCCCCEEEEECCEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
FTLIGPKRYDAPWKEIEAQGWIAPADCVEVRVSLSESDRMACAMAEPDVRYRMAATLPIK
EEEECCCCCCCCHHHHCCCCCCCCHHHEEEEEECCCCCCEEEEECCCCCEEEEEEECCHH
NKVVRDLVERHRGQPTLVIGQYVDQLEELAAELKCPIITGSTTPTRRQEIYQDFREGQID
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEE
LLVVSKVANFSIDLPSAEVAIQVSGAFGSRQEEAQRLGRLLRPKEGLVARFYAVVSRDTV
EEEEEECCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
DTDFASHRQRFLAEQGYSYRIIDADDLDALDRTA
CHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA