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The map label for this gene is yiaE [C]

Identifier: 50841862

GI number: 50841862

Start: 425575

End: 425880

Strand: Direct

Name: yiaE [C]

Synonym: PPA0379

Alternate gene names: 50841862

Gene position: 425575-425880 (Clockwise)

Preceding gene: 50841859

Following gene: 50841864

Centisome position: 16.62

GC content: 65.36

Gene sequence:

>306_bases
ATGAAGGACGGAGCGACTTTCATCAACACTGCGCGCGGGGCCATCTGTGATCAGGACGCCCTCATCGCTGAACTGCAGCG
CGACCGGATCAGCGCCATCATCGACGTGACCGACCCCGAGGTCAACGCGCCCGACTCCCCATTGTGGACCCTGCCGAACG
TCATCCTGACCCCACACGCTGCCGGGTCAATGGGACGAGAGCTTCACCGCCTCGGCGACGGCGCGGTCGATGACCTGGCG
AATTACATTTCCGGTGCCCCCGTGGCCGGGGAATTCCCGGTCGGTCAGTACGCGGGGCGTGCCTGA

Upstream 100 bases:

>100_bases
GGCGGTGCGCAGAGCTCGGTAGCGACGTGACGTCGTCTCCCTGCACTCGGCGTCGACGCCGCAGACCTACCACATGCTGG
GAGCTGAGGATTTCGCGAAG

Downstream 100 bases:

>100_bases
TGAAGCGGGACGTGACTTGGGTTAGCGGCAATCTAGTTAGGTGAGGCGGCACATCAGGCTCGGTCGTGGCGGCCGCCGCC
GGAGGGAGTTTGAGTTACCT

Product: putative dehydrogenase

Products: glycerate; NADP; NADPH; glyoxylate; 2-Dehydro-D-gluconate; 5-ketogluconate; L-idonate [C]

Alternate protein names: 2-Hydroxyacid-Family Dehydrogenase; 2-Hydroxyacid Family Dehydrogenase; 2-Hydroxyacid Dehydrogenase; Phosphoglycerate Dehydrogenase-Like Oxidoreductase; Glycerate Dehydrogenase; Oxidoreductase; Phosphoglycerate Dehydrogenase; Oxidoreductase Protein; Phosphoglycerate Dehydrogenase Or Related Dehydrogenase; Glycerate Dehydrogenase/Glyoxylate Reductase; D-Isomer Specific 2-Hydroxyacid Dehydrogenase; Dehydrogenase Protein; Erythronate-4-Phosphate Dehydrogenase Domain Protein; D-2-Hydroxyacid Dehydrogenase Protein; D-3-Phosphoglycerate Dehydrogenase

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MKDGATFINTARGAICDQDALIAELQRDRISAIIDVTDPEVNAPDSPLWTLPNVILTPHAAGSMGRELHRLGDGAVDDLA
NYISGAPVAGEFPVGQYAGRA

Sequences:

>Translated_101_residues
MKDGATFINTARGAICDQDALIAELQRDRISAIIDVTDPEVNAPDSPLWTLPNVILTPHAAGSMGRELHRLGDGAVDDLA
NYISGAPVAGEFPVGQYAGRA
>Mature_101_residues
MKDGATFINTARGAICDQDALIAELQRDRISAIIDVTDPEVNAPDSPLWTLPNVILTPHAAGSMGRELHRLGDGAVDDLA
NYISGAPVAGEFPVGQYAGRA

Specific function: Unknown

COG id: COG0111

COG function: function code HE; Phosphoglycerate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082289, Length=86, Percent_Identity=38.3720930232558, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 10614; Mature: 10614

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDGATFINTARGAICDQDALIAELQRDRISAIIDVTDPEVNAPDSPLWTLPNVILTPHA
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCEEECCCC
AGSMGRELHRLGDGAVDDLANYISGAPVAGEFPVGQYAGRA
CCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKDGATFINTARGAICDQDALIAELQRDRISAIIDVTDPEVNAPDSPLWTLPNVILTPHA
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCEEECCCC
AGSMGRELHRLGDGAVDDLANYISGAPVAGEFPVGQYAGRA
CCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate; NADPH; glycolate; NADP; gluconate; 2,5-diketo-D-gluconate; 2-keto-L-gulonate [C]

Specific reaction: hydroxypyruvate + NADPH = glycerate + NADP glycolate + NADP = NADPH + glyoxylate NADP + gluconate = NADPH + 2-Dehydro-D-gluconate 2,5-diketo-D-gluconate + NADPH = 5-ketogluconate + NADP 2-keto-L-gulonate + NADPH = L-idonate + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA