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The map label for this gene is ansA [H]

Identifier: 50841852

GI number: 50841852

Start: 413845

End: 414840

Strand: Reverse

Name: ansA [H]

Synonym: PPA0367

Alternate gene names: 50841852

Gene position: 414840-413845 (Counterclockwise)

Preceding gene: 50841853

Following gene: 50841851

Centisome position: 16.2

GC content: 59.34

Gene sequence:

>996_bases
ATGATGCAAACCCACGTTCTCTACACCGGCGGAACGTTAGGAATGGTGTCCACTCCTAACGGCTTAGCTCCAGGTGCTGA
TCTGACGGGTTGGCTTAACCAATTACTATCTGGCACCGAACTCGCCGGAACCTTTGAGACCCTGAGTTTCGAGCATCTCA
TTGACTCGGCCAACGCCACTCCCGATGACTGGCGCCGAATTGTCGACGATCTGTGGGAGCATCGCGACGATGCCGACTCA
TTCGTTGTTCTTCATGGAACCGACACCTTGGCCTACACCTCAGCCGCGCTGTCCTACGCCCTTACCGAGTTCGGTAAGCC
GGTCGTCGTCACCGGAGCACAGTACTCATTGGGAGTCGTCGGAACAGATGCTGCGCCAAACGTCACGGGAGCGCTGCGAG
CCGCCACGAGCGGGCGCCTCAACGGGGTCGCGGTCTTCTTTGGCCACAAACTGCTGCGTGGCAATCGCGTCACGAAACTC
TCCTCGTGGGCCTATAACGGGTTCGATTCGCCCGCCGTCCCACAATTAGCGCGCACCGGAGCACCGTGGCAATGGGTCGA
GAATGAATCGACGGGTTGCGGTTGGCTCAACCCCGGCCCATACCAGCGTCACGACGTCCTCGTCGTTGATCTATCTCCGG
GCATCAGCGCTCGACGCCTCCGCGCCGTCCTCGACCCTTTGCCCGAAGCCGTTATCTTGCGCGCATTCGGAGTCGGAAAT
ATCCCCAGTGATGAACCCGGCGTCGTCGACGCCATCCTCGATGTCATCTCCGCCGGCACCCCCGTCGTCGTCGCTTCCCA
ATGCATGCAAGCTGATGTCCAACTGGGTCAATACCAGTCAAGTCATGCCCTCACGGAGGGCGGAGCTGTCAGCGCCCATG
ACATGACTCTCGAGGCTCTCTATGCCAAGCTAATCTTTCTGCTCTCTCAAGGGCTGCACGGCAAAGAGCTCAAGCGATGG
ATCGAGACCGACATCGCTGGTGAGATCAGCGTCTAA

Upstream 100 bases:

>100_bases
CCTGGTCGCAATTGCCATGGTCGCCGGGTGGTACGCAGTCCGTAACAGCATCAAACCCGACCTGCTCGACAACGTGGTTC
CAAGCGATGAGGGGATGTGA

Downstream 100 bases:

>100_bases
TTATCACACTTTCCCACCAAGGGCCCAGTTTTGATGCACGTTCGTCGCAAAAAGTGTGAGATTTTCCGCTAGCACTAGCT
AACGGCCTGTCCGTGGACAA

Product: L-asparaginase I

Products: NA

Alternate protein names: L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MMQTHVLYTGGTLGMVSTPNGLAPGADLTGWLNQLLSGTELAGTFETLSFEHLIDSANATPDDWRRIVDDLWEHRDDADS
FVVLHGTDTLAYTSAALSYALTEFGKPVVVTGAQYSLGVVGTDAAPNVTGALRAATSGRLNGVAVFFGHKLLRGNRVTKL
SSWAYNGFDSPAVPQLARTGAPWQWVENESTGCGWLNPGPYQRHDVLVVDLSPGISARRLRAVLDPLPEAVILRAFGVGN
IPSDEPGVVDAILDVISAGTPVVVASQCMQADVQLGQYQSSHALTEGGAVSAHDMTLEALYAKLIFLLSQGLHGKELKRW
IETDIAGEISV

Sequences:

>Translated_331_residues
MMQTHVLYTGGTLGMVSTPNGLAPGADLTGWLNQLLSGTELAGTFETLSFEHLIDSANATPDDWRRIVDDLWEHRDDADS
FVVLHGTDTLAYTSAALSYALTEFGKPVVVTGAQYSLGVVGTDAAPNVTGALRAATSGRLNGVAVFFGHKLLRGNRVTKL
SSWAYNGFDSPAVPQLARTGAPWQWVENESTGCGWLNPGPYQRHDVLVVDLSPGISARRLRAVLDPLPEAVILRAFGVGN
IPSDEPGVVDAILDVISAGTPVVVASQCMQADVQLGQYQSSHALTEGGAVSAHDMTLEALYAKLIFLLSQGLHGKELKRW
IETDIAGEISV
>Mature_331_residues
MMQTHVLYTGGTLGMVSTPNGLAPGADLTGWLNQLLSGTELAGTFETLSFEHLIDSANATPDDWRRIVDDLWEHRDDADS
FVVLHGTDTLAYTSAALSYALTEFGKPVVVTGAQYSLGVVGTDAAPNVTGALRAATSGRLNGVAVFFGHKLLRGNRVTKL
SSWAYNGFDSPAVPQLARTGAPWQWVENESTGCGWLNPGPYQRHDVLVVDLSPGISARRLRAVLDPLPEAVILRAFGVGN
IPSDEPGVVDAILDVISAGTPVVVASQCMQADVQLGQYQSSHALTEGGAVSAHDMTLEALYAKLIFLLSQGLHGKELKRW
IETDIAGEISV

Specific function: Unknown

COG id: COG0252

COG function: function code EJ; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the asparaginase 1 family [H]

Homologues:

Organism=Homo sapiens, GI122937331, Length=350, Percent_Identity=31.4285714285714, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1788065, Length=334, Percent_Identity=36.5269461077844, Blast_Score=207, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17558280, Length=359, Percent_Identity=31.7548746518106, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193207372, Length=359, Percent_Identity=31.7548746518106, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17558278, Length=359, Percent_Identity=31.7548746518106, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193207374, Length=359, Percent_Identity=31.7548746518106, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24639609, Length=364, Percent_Identity=32.967032967033, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24645530, Length=338, Percent_Identity=32.5443786982249, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006033
- InterPro:   IPR006034
- InterPro:   IPR020827 [H]

Pfam domain/function: PF00710 Asparaginase [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 35235; Mature: 35235

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTHVLYTGGTLGMVSTPNGLAPGADLTGWLNQLLSGTELAGTFETLSFEHLIDSANAT
CCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PDDWRRIVDDLWEHRDDADSFVVLHGTDTLAYTSAALSYALTEFGKPVVVTGAQYSLGVV
HHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEE
GTDAAPNVTGALRAATSGRLNGVAVFFGHKLLRGNRVTKLSSWAYNGFDSPAVPQLARTG
ECCCCCCCHHHHHHHCCCCCCCEEEEECHHHHCCCCCEEEHHCCCCCCCCCCCHHHHHCC
APWQWVENESTGCGWLNPGPYQRHDVLVVDLSPGISARRLRAVLDPLPEAVILRAFGVGN
CCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHCCCC
IPSDEPGVVDAILDVISAGTPVVVASQCMQADVQLGQYQSSHALTEGGAVSAHDMTLEAL
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
YAKLIFLLSQGLHGKELKRWIETDIAGEISV
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMQTHVLYTGGTLGMVSTPNGLAPGADLTGWLNQLLSGTELAGTFETLSFEHLIDSANAT
CCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PDDWRRIVDDLWEHRDDADSFVVLHGTDTLAYTSAALSYALTEFGKPVVVTGAQYSLGVV
HHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEE
GTDAAPNVTGALRAATSGRLNGVAVFFGHKLLRGNRVTKLSSWAYNGFDSPAVPQLARTG
ECCCCCCCHHHHHHHCCCCCCCEEEEECHHHHCCCCCEEEHHCCCCCCCCCCCHHHHHCC
APWQWVENESTGCGWLNPGPYQRHDVLVVDLSPGISARRLRAVLDPLPEAVILRAFGVGN
CCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHCCCC
IPSDEPGVVDAILDVISAGTPVVVASQCMQADVQLGQYQSSHALTEGGAVSAHDMTLEAL
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
YAKLIFLLSQGLHGKELKRWIETDIAGEISV
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]