Click here to switch to the map view.

The map label for this gene is regX3 [H]

Identifier: 50841845

GI number: 50841845

Start: 407773

End: 408453

Strand: Reverse

Name: regX3 [H]

Synonym: PPA0359

Alternate gene names: 50841845

Gene position: 408453-407773 (Counterclockwise)

Preceding gene: 50841846

Following gene: 50841843

Centisome position: 15.95

GC content: 59.77

Gene sequence:

>681_bases
ATGACCCGCGTACTCATCATCGAGGACGAAGAGTCCTATCGCGAGGCCACCGCCTTCATGCTGCGCAAAGAGGGATTTGA
GGTCAACACTGCCGCCAATGGCGCTGATGGCCTCGAAATCTACTCGCGCAACGGTGCCGACATCGTGCTGCTCGACCTCA
TGATGCCGGGGCTTCCAGGGACCGAAGTCTGCCGTCAGCTACGCCAGCGCGGCAATGTCGGGATCATCATGGTGACGGCT
AGAGATTCGGAGATCGACAAGGTTGTCGGGCTGGAGCTCGGAGCCGACGACTACGTCACCAAACCGTTTAGCCACCGAGA
ATTGGTCGCGCGCATCCGCGCTGTGACTCGTCGTGGCAGCCCCGAAGTAGAAGTTTCCCCCGATGTTCTCGAGGAGAGCG
GGGTAAGGATGGACGTCGAGCGGCACGAGGTCAGCGTCGAGGGGACGGTAGTGCGACTTGCCCTCAAAGAGTTCGACCTG
CTTGAGGTGCTGCTGCGCAATGCAGGACGCGTCATGACCCGAGCCTCCCTCATCGACCGAGTGTGGGGAGCCGACTATGT
TGGCGACACTAAAACTCTTGACGTGCACATCAAAAGGCTGCGCGCAAAGATTGAAGATGACCCATCCCGTCCGGTGCGCA
TCACCACCGTACGCGGACTGGGCTACAAGTTTCAGGCCTAA

Upstream 100 bases:

>100_bases
CTGTCGATGTGTGGAGCAAGTTGGGCCAGGGGTCCACGTTCACCCTTCGACTTCCAACCCTCGACGTTGATCACCACAAC
GAATCCGATCAGGAGGAGTC

Downstream 100 bases:

>100_bases
AGCATCACCACCCAGGAAAGCAACACCACGCAGGAATGGTGTATTCAGCTGATTAGGACCGAGCCGACGGAATTCCTGAA
GAAGCGTACTCCGCAAAGTC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTRVLIIEDEESYREATAFMLRKEGFEVNTAANGADGLEIYSRNGADIVLLDLMMPGLPGTEVCRQLRQRGNVGIIMVTA
RDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRRGSPEVEVSPDVLEESGVRMDVERHEVSVEGTVVRLALKEFDL
LEVLLRNAGRVMTRASLIDRVWGADYVGDTKTLDVHIKRLRAKIEDDPSRPVRITTVRGLGYKFQA

Sequences:

>Translated_226_residues
MTRVLIIEDEESYREATAFMLRKEGFEVNTAANGADGLEIYSRNGADIVLLDLMMPGLPGTEVCRQLRQRGNVGIIMVTA
RDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRRGSPEVEVSPDVLEESGVRMDVERHEVSVEGTVVRLALKEFDL
LEVLLRNAGRVMTRASLIDRVWGADYVGDTKTLDVHIKRLRAKIEDDPSRPVRITTVRGLGYKFQA
>Mature_225_residues
TRVLIIEDEESYREATAFMLRKEGFEVNTAANGADGLEIYSRNGADIVLLDLMMPGLPGTEVCRQLRQRGNVGIIMVTAR
DSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRRGSPEVEVSPDVLEESGVRMDVERHEVSVEGTVVRLALKEFDLL
EVLLRNAGRVMTRASLIDRVWGADYVGDTKTLDVHIKRLRAKIEDDPSRPVRITTVRGLGYKFQA

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=39.2857142857143, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.647577092511, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=37.4449339207048, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=36.6071428571429, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=38.6666666666667, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=38.8392857142857, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=34.2105263157895, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.7713004484305, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=35.3711790393013, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=38.034188034188, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.9775784753363, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=34.375, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=31.3304721030043, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=32.4444444444444, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=36.036036036036, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.8965517241379, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25295; Mature: 25164

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLIIEDEESYREATAFMLRKEGFEVNTAANGADGLEIYSRNGADIVLLDLMMPGLPG
CCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCH
TEVCRQLRQRGNVGIIMVTARDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRRGS
HHHHHHHHHCCCEEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
PEVEVSPDVLEESGVRMDVERHEVSVEGTVVRLALKEFDLLEVLLRNAGRVMTRASLIDR
CCEEECHHHHHHCCCEEEEHHHEEEECCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
VWGADYVGDTKTLDVHIKRLRAKIEDDPSRPVRITTVRGLGYKFQA
HHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure 
TRVLIIEDEESYREATAFMLRKEGFEVNTAANGADGLEIYSRNGADIVLLDLMMPGLPG
CEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCH
TEVCRQLRQRGNVGIIMVTARDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRRGS
HHHHHHHHHCCCEEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
PEVEVSPDVLEESGVRMDVERHEVSVEGTVVRLALKEFDLLEVLLRNAGRVMTRASLIDR
CCEEECHHHHHHCCCEEEEHHHEEEECCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
VWGADYVGDTKTLDVHIKRLRAKIEDDPSRPVRITTVRGLGYKFQA
HHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA