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The map label for this gene is ptsG [H]

Identifier: 50841782

GI number: 50841782

Start: 342413

End: 342886

Strand: Reverse

Name: ptsG [H]

Synonym: PPA0293

Alternate gene names: 50841782

Gene position: 342886-342413 (Counterclockwise)

Preceding gene: 50841783

Following gene: 50841781

Centisome position: 13.39

GC content: 64.35

Gene sequence:

>474_bases
ATGTCCATTTTTCGCAAGCGCCGCAAGGCCACACCCCTGACCATCGCAGCACCGGTCTCGGGCGAGATCATCGATATTGC
TGACGTACCGGACCCGGTATTCGCAGGCAAGCACATGGGCCCAGGCTTTGCGGTCGCCCCGGTCTCGGGCGACTTCACCT
CGCCCATCGACGGCATCGTCATACTTGTCGCGCCGACCCTCCACGCCGTCGGCCTGCGCGCAGACAATGGGGCGGAGGTT
CTGGTCCACGTCGGCGTCGACACCGTTGAGCTGAAGGGTGAAGGTTTCACTGCCCACGTCAACGAGGGCGACAGGGTCAG
GACCGGCGATCCGCTCCTGAGCGTCGACCTGGACAGCATACGGCCACGCGTACCGTCGCTGATCTCCCCCGTGGTCGTGA
CCAACGCGGCCGGGTTCACCATCTCGGAACGCAGCAATGATCCGGCGTCAGTGCTCTCAGTCACCGCAGGATGA

Upstream 100 bases:

>100_bases
AGGTCGGCGGCGGAGTCCAGGCCGTCTACGGAGCCAAAGCCATCCTCTACAAGAACGCCATCAACGCCCAACTCGGAATC
GACGACTGAAAGGTGTCGAC

Downstream 100 bases:

>100_bases
CCCGGTGCAACGCCCGGATCGCTCACGGTACGCAACGACGAAGCAGGGATCGCTCAGACCCGGGCACGTCATCGTCAAGA
AGATTTACAACAACAATGTC

Product: PTS system, glucose/sucrose specific IIA subunit

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSIFRKRRKATPLTIAAPVSGEIIDIADVPDPVFAGKHMGPGFAVAPVSGDFTSPIDGIVILVAPTLHAVGLRADNGAEV
LVHVGVDTVELKGEGFTAHVNEGDRVRTGDPLLSVDLDSIRPRVPSLISPVVVTNAAGFTISERSNDPASVLSVTAG

Sequences:

>Translated_157_residues
MSIFRKRRKATPLTIAAPVSGEIIDIADVPDPVFAGKHMGPGFAVAPVSGDFTSPIDGIVILVAPTLHAVGLRADNGAEV
LVHVGVDTVELKGEGFTAHVNEGDRVRTGDPLLSVDLDSIRPRVPSLISPVVVTNAAGFTISERSNDPASVLSVTAG
>Mature_156_residues
SIFRKRRKATPLTIAAPVSGEIIDIADVPDPVFAGKHMGPGFAVAPVSGDFTSPIDGIVILVAPTLHAVGLRADNGAEVL
VHVGVDTVELKGEGFTAHVNEGDRVRTGDPLLSVDLDSIRPRVPSLISPVVVTNAAGFTISERSNDPASVLSVTAG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=129, Percent_Identity=42.6356589147287, Blast_Score=115, Evalue=9e-28,
Organism=Escherichia coli, GI1790159, Length=126, Percent_Identity=44.4444444444444, Blast_Score=114, Evalue=2e-27,
Organism=Escherichia coli, GI1786894, Length=126, Percent_Identity=40.4761904761905, Blast_Score=103, Evalue=7e-24,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16225; Mature: 16094

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFRKRRKATPLTIAAPVSGEIIDIADVPDPVFAGKHMGPGFAVAPVSGDFTSPIDGIV
CCCHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEE
ILVAPTLHAVGLRADNGAEVLVHVGVDTVELKGEGFTAHVNEGDRVRTGDPLLSVDLDSI
EEEECCEEEEEEECCCCCEEEEEECCEEEEECCCCEEEECCCCCEEECCCCEEEEEHHHC
RPRVPSLISPVVVTNAAGFTISERSNDPASVLSVTAG
CCCCCHHHCCEEEECCCCEEEECCCCCCCCEEEEECC
>Mature Secondary Structure 
SIFRKRRKATPLTIAAPVSGEIIDIADVPDPVFAGKHMGPGFAVAPVSGDFTSPIDGIV
CCHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEE
ILVAPTLHAVGLRADNGAEVLVHVGVDTVELKGEGFTAHVNEGDRVRTGDPLLSVDLDSI
EEEECCEEEEEEECCCCCEEEEEECCEEEEECCCCEEEECCCCCEEECCCCEEEEEHHHC
RPRVPSLISPVVVTNAAGFTISERSNDPASVLSVTAG
CCCCCHHHCCEEEECCCCEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]