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The map label for this gene is glcB [H]

Identifier: 50841783

GI number: 50841783

Start: 342898

End: 344577

Strand: Reverse

Name: glcB [H]

Synonym: PPA0294

Alternate gene names: 50841783

Gene position: 344577-342898 (Counterclockwise)

Preceding gene: 50841784

Following gene: 50841782

Centisome position: 13.46

GC content: 58.57

Gene sequence:

>1680_bases
GTGCCAACTCGGTCCGCGACATTAAGGCAATCCTGTCCACCGGAGCCGACATCGTTGCCGTTGGTGGCACAATCACCCGT
CCCGCCCACATCTGCACCCACTTCATCGACGCGATTCGCGCCCGCATCCCCCACACGTCGTTGGAGAACTGACATGTTCA
AGACTCTGCAGAAGATCGGTAAGGCGTTCATGCTACCGATCGCCATCCTCCCTGCCGCAGGTCTGCTGCTAGGGATCGGT
GGTGCGCTGTCCAACCCCACCACTGTCAAGAGCTACCCAGTTCTCGACAATCCCATCCTCCAAGACATCTTCCAGGTAAT
GAGCGCAGCTGGAAATGTCATCTTCGAAAACCTTGCCCTGCTACTGTCCATCGGCTTGTGCATCGGCCTGGCAAAACGTG
ACAAGGGAACCGCGGCACTCGCCGGCATCACCGGTTTCCTGGTCATGACAGCCACCACGAAGGCGCTTGTCGTTCTCTCC
CGTCACCCCGATCGGACAATCGACACCGGTGTCGTTGGTTCACTCGTCATCGGTGCCATCGCCGTATGGCTTCACAACCG
CTATCACAACATCGAGCTCCCCGCTTTCCTCGGGTTCTTCGGAGGCTCACGCTTCGTTCCCATTGTTACGGCTTTCGCGG
GAATCATCATTGGCGCATTCTTCTTTGTCGTCTGGCCACCAATCCAGGCCGGGATGGTGTCAGCCGGCACTGCGATCGCC
GACTGGGGTGTCATTGGTACGTTCTTCTATGGCTTCCTCATGCGGCTAGCCGGCGCCGTCGGCCTTCACCACATGATCTA
TCCGATGTTCTGGTACACACCCCTCGGCGGTACCGAGGCAGTCGCCGGCAAAACGGTTGTAGGCGCACAGAAGATTTTCT
TCGCCCAGCTGGCTGATCCCAACCATGTCGGACTGTTCACCCATTCCACCAAGTACTTTGCCGGTCGCTTCGCCACCATG
ATGTTTGGACTGCCTGGGGCCTGTCTGGCGATGTGGCGCTGCGTTCCCAAGGGGCGTCGCGCCAAGTACACCGGATTGTT
CGCCTCCGTCGCCTTCACGTCCTTCCTGACCGGAATCACCGAACCCATCGAATACATGTTCCTCTTCGTGGCCCCGCTGC
TCTACGTGTTCCATTCGGTCCTCGATGGCGTCTCCTTCCTGGTGGCGGACCTCATCAACATTCGTATTGGCAATACCTTC
TCGGGTGGTGCTATCGACTACCTCCTGTTCGGTGTGCTGCAAGGTGAGGCCAAGACCCACTGGCTGTATGTGTTGCCTGT
CGGCGCGCTCTGGTTCGTCATCTACTATTTCTCCTTCACCTTTTTCATCAAGAAATTCCGGATCGCCACCCCGGGACATC
TCGAGGACACCATGACTGCCGCCACACCCACCGATAGAAGGTCCCAGGAAAAGTCCGAGCGGAGGAACGACGGGATCGAC
GAGACAGCGGCGGAGATCATCACTGCCTTGGGCGGTGCCGAGAACATCGAGGACGTCGACGCGTGCATCACGCGTCTGCG
TGTGTCAGTAAAAGCGCCTGATCAGGTCAGCAAAGCCAGCCTCAAGAATCTCGGAGCGACCGAGGTCTTCGAGGTCGGCG
GCGGAGTCCAGGCCGTCTACGGAGCCAAAGCCATCCTCTACAAGAACGCCATCAACGCCCAACTCGGAATCGACGACTGA

Upstream 100 bases:

>100_bases
CCGTGCCAGACATTGCCTGGTGAACCCATACATTCCGAGAGTGGTGGCGTCACGCCCCTATTCGCGACGGCAGCTGCGCA
GTCCGGGGCCGTCAACATCC

Downstream 100 bases:

>100_bases
AAGGTGTCGACATGTCCATTTTTCGCAAGCGCCGCAAGGCCACACCCCTGACCATCGCAGCACCGGTCTCGGGCGAGATC
ATCGATATTGCTGACGTACC

Product: PTS system sugar-specific EII component

Products: NA

Alternate protein names: Glucoside permease IIC component; PTS system glucoside-specific EIIC component; Glucoside-specific phosphotransferase enzyme IIB component; PTS system glucoside-specific EIIB component; Glucoside-specific phosphotransferase enzyme IIA component; PTS system glucoside-specific EIIA component [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MPTRSATLRQSCPPEPTSLPLVAQSPVPPTSAPTSSTRFAPASPTRRWRTDMFKTLQKIGKAFMLPIAILPAAGLLLGIG
GALSNPTTVKSYPVLDNPILQDIFQVMSAAGNVIFENLALLLSIGLCIGLAKRDKGTAALAGITGFLVMTATTKALVVLS
RHPDRTIDTGVVGSLVIGAIAVWLHNRYHNIELPAFLGFFGGSRFVPIVTAFAGIIIGAFFFVVWPPIQAGMVSAGTAIA
DWGVIGTFFYGFLMRLAGAVGLHHMIYPMFWYTPLGGTEAVAGKTVVGAQKIFFAQLADPNHVGLFTHSTKYFAGRFATM
MFGLPGACLAMWRCVPKGRRAKYTGLFASVAFTSFLTGITEPIEYMFLFVAPLLYVFHSVLDGVSFLVADLINIRIGNTF
SGGAIDYLLFGVLQGEAKTHWLYVLPVGALWFVIYYFSFTFFIKKFRIATPGHLEDTMTAATPTDRRSQEKSERRNDGID
ETAAEIITALGGAENIEDVDACITRLRVSVKAPDQVSKASLKNLGATEVFEVGGGVQAVYGAKAILYKNAINAQLGIDD

Sequences:

>Translated_559_residues
MPTRSATLRQSCPPEPTSLPLVAQSPVPPTSAPTSSTRFAPASPTRRWRTDMFKTLQKIGKAFMLPIAILPAAGLLLGIG
GALSNPTTVKSYPVLDNPILQDIFQVMSAAGNVIFENLALLLSIGLCIGLAKRDKGTAALAGITGFLVMTATTKALVVLS
RHPDRTIDTGVVGSLVIGAIAVWLHNRYHNIELPAFLGFFGGSRFVPIVTAFAGIIIGAFFFVVWPPIQAGMVSAGTAIA
DWGVIGTFFYGFLMRLAGAVGLHHMIYPMFWYTPLGGTEAVAGKTVVGAQKIFFAQLADPNHVGLFTHSTKYFAGRFATM
MFGLPGACLAMWRCVPKGRRAKYTGLFASVAFTSFLTGITEPIEYMFLFVAPLLYVFHSVLDGVSFLVADLINIRIGNTF
SGGAIDYLLFGVLQGEAKTHWLYVLPVGALWFVIYYFSFTFFIKKFRIATPGHLEDTMTAATPTDRRSQEKSERRNDGID
ETAAEIITALGGAENIEDVDACITRLRVSVKAPDQVSKASLKNLGATEVFEVGGGVQAVYGAKAILYKNAINAQLGIDD
>Mature_558_residues
PTRSATLRQSCPPEPTSLPLVAQSPVPPTSAPTSSTRFAPASPTRRWRTDMFKTLQKIGKAFMLPIAILPAAGLLLGIGG
ALSNPTTVKSYPVLDNPILQDIFQVMSAAGNVIFENLALLLSIGLCIGLAKRDKGTAALAGITGFLVMTATTKALVVLSR
HPDRTIDTGVVGSLVIGAIAVWLHNRYHNIELPAFLGFFGGSRFVPIVTAFAGIIIGAFFFVVWPPIQAGMVSAGTAIAD
WGVIGTFFYGFLMRLAGAVGLHHMIYPMFWYTPLGGTEAVAGKTVVGAQKIFFAQLADPNHVGLFTHSTKYFAGRFATMM
FGLPGACLAMWRCVPKGRRAKYTGLFASVAFTSFLTGITEPIEYMFLFVAPLLYVFHSVLDGVSFLVADLINIRIGNTFS
GGAIDYLLFGVLQGEAKTHWLYVLPVGALWFVIYYFSFTFFIKKFRIATPGHLEDTMTAATPTDRRSQEKSERRNDGIDE
TAAEIITALGGAENIEDVDACITRLRVSVKAPDQVSKASLKNLGATEVFEVGGGVQAVYGAKAILYKNAINAQLGIDD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=523, Percent_Identity=37.6673040152964, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI1787343, Length=506, Percent_Identity=36.9565217391304, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1786894, Length=489, Percent_Identity=38.0368098159509, Blast_Score=267, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 60174; Mature: 60043

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRSATLRQSCPPEPTSLPLVAQSPVPPTSAPTSSTRFAPASPTRRWRTDMFKTLQKIG
CCCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KAFMLPIAILPAAGLLLGIGGALSNPTTVKSYPVLDNPILQDIFQVMSAAGNVIFENLAL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLSIGLCIGLAKRDKGTAALAGITGFLVMTATTKALVVLSRHPDRTIDTGVVGSLVIGAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHH
AVWLHNRYHNIELPAFLGFFGGSRFVPIVTAFAGIIIGAFFFVVWPPIQAGMVSAGTAIA
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHCCCHHH
DWGVIGTFFYGFLMRLAGAVGLHHMIYPMFWYTPLGGTEAVAGKTVVGAQKIFFAQLADP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHCCCCC
NHVGLFTHSTKYFAGRFATMMFGLPGACLAMWRCVPKGRRAKYTGLFASVAFTSFLTGIT
CCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
EPIEYMFLFVAPLLYVFHSVLDGVSFLVADLINIRIGNTFSGGAIDYLLFGVLQGEAKTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCCE
WLYVLPVGALWFVIYYFSFTFFIKKFRIATPGHLEDTMTAATPTDRRSQEKSERRNDGID
EEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCH
ETAAEIITALGGAENIEDVDACITRLRVSVKAPDQVSKASLKNLGATEVFEVGGGVQAVY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHCCCCCHHHH
GAKAILYKNAINAQLGIDD
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PTRSATLRQSCPPEPTSLPLVAQSPVPPTSAPTSSTRFAPASPTRRWRTDMFKTLQKIG
CCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH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HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA