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The map label for this gene is cobK [H]

Identifier: 161621799

GI number: 161621799

Start: 484460

End: 485212

Strand: Reverse

Name: cobK [H]

Synonym: PPA0440

Alternate gene names: 161621799

Gene position: 485212-484460 (Counterclockwise)

Preceding gene: 50841927

Following gene: 50841919

Centisome position: 18.95

GC content: 63.35

Gene sequence:

>753_bases
ATGGACGTCCTCATTCTCGGCGGTACGACGAAGGCCCGGCAGTTAGCCACCCGATTGATCGATGAGGGGGTAGACCTGTG
CAGCTCGTTAGCGGGGCGCACGAAGTCCCCCCGGCCAGTTCCTGGCCCGACTCGGGTGGGTGGTTTCGGCGGCATCGACG
GTCTCAAAGAATTCCTGACTGACAACGAAGTCAAGGTCATGGTGGATGCCTCCCACCCCTTCGCAGCAGCTATGCACGGC
CACGCCGCTCAAGCATGCCGCGACCTCAACCTTCCGCTGGCACGGCTGGCACCACCAAGCTGGCGTACCCAACCTGAGGC
AGCGACCTGGCACTGGGTTGACGACCACGACGGTGCTGCTCAAGTCTTAGCTGACTTACCCGACGTCATCCTGCTGACGG
TGGGACGCCAACCCGTCAGTCACTACCTGAGACTCGGCCCACGTCGGGTGATCGTGCGCTGCGTCGATGCCCCCGAGGAG
GAGCTTCCCGCAGGCTGGAAGGTACTGCGGGAGCGTGGTCCGTTCACCCTCGACCGCGAGCGAGAGATTTTCTCGCAGGG
TGTGGCTACCCTCGTCTCCAAGGATTCCGGAGGCACCGGTCTCGACCCTAAACTCAGGTTGGCGGCCGAAACCGACGTCC
AGGTCGTCATGGTCTCACGTGGTCCGGCGCCCGGCTGGGGGGATGAGCTCAGCACCGTTGACGACGCAGTGCAGTGGACA
GGAAACCACATCGCCACCGTGATTGAGCAGTAA

Upstream 100 bases:

>100_bases
TTCGCCCAAGAGGCGTCACAGTGGCGGGACCGTCCCGGATTCACACCGGTGTTCCACCGCGATTGAGGCTCATTGTTCCA
CAGGCTGGTTTGATGGACTC

Downstream 100 bases:

>100_bases
TCCCTCACGGAGCACTATTTCAGTGATCAGACGGGACGTGGGCCTGGGTCCCGTCGAGGTCAAGCCCGGCGACATCGCCG
ACGACGGTGATGGCCGGCGG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MDVLILGGTTKARQLATRLIDEGVDLCSSLAGRTKSPRPVPGPTRVGGFGGIDGLKEFLTDNEVKVMVDASHPFAAAMHG
HAAQACRDLNLPLARLAPPSWRTQPEAATWHWVDDHDGAAQVLADLPDVILLTVGRQPVSHYLRLGPRRVIVRCVDAPEE
ELPAGWKVLRERGPFTLDREREIFSQGVATLVSKDSGGTGLDPKLRLAAETDVQVVMVSRGPAPGWGDELSTVDDAVQWT
GNHIATVIEQ

Sequences:

>Translated_250_residues
MDVLILGGTTKARQLATRLIDEGVDLCSSLAGRTKSPRPVPGPTRVGGFGGIDGLKEFLTDNEVKVMVDASHPFAAAMHG
HAAQACRDLNLPLARLAPPSWRTQPEAATWHWVDDHDGAAQVLADLPDVILLTVGRQPVSHYLRLGPRRVIVRCVDAPEE
ELPAGWKVLRERGPFTLDREREIFSQGVATLVSKDSGGTGLDPKLRLAAETDVQVVMVSRGPAPGWGDELSTVDDAVQWT
GNHIATVIEQ
>Mature_250_residues
MDVLILGGTTKARQLATRLIDEGVDLCSSLAGRTKSPRPVPGPTRVGGFGGIDGLKEFLTDNEVKVMVDASHPFAAAMHG
HAAQACRDLNLPLARLAPPSWRTQPEAATWHWVDDHDGAAQVLADLPDVILLTVGRQPVSHYLRLGPRRVIVRCVDAPEE
ELPAGWKVLRERGPFTLDREREIFSQGVATLVSKDSGGTGLDPKLRLAAETDVQVVMVSRGPAPGWGDELSTVDDAVQWT
GNHIATVIEQ

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26965; Mature: 26965

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLILGGTTKARQLATRLIDEGVDLCSSLAGRTKSPRPVPGPTRVGGFGGIDGLKEFLT
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
DNEVKVMVDASHPFAAAMHGHAAQACRDLNLPLARLAPPSWRTQPEAATWHWVDDHDGAA
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCEEEEECCCCCHH
QVLADLPDVILLTVGRQPVSHYLRLGPRRVIVRCVDAPEEELPAGWKVLRERGPFTLDRE
HHHHCCCCEEEEECCCCHHHHHHHCCCHHEEEEECCCCHHHCCHHHHHHHHCCCCCCCHH
REIFSQGVATLVSKDSGGTGLDPKLRLAAETDVQVVMVSRGPAPGWGDELSTVDDAVQWT
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHC
GNHIATVIEQ
CCHHEEEECC
>Mature Secondary Structure
MDVLILGGTTKARQLATRLIDEGVDLCSSLAGRTKSPRPVPGPTRVGGFGGIDGLKEFLT
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
DNEVKVMVDASHPFAAAMHGHAAQACRDLNLPLARLAPPSWRTQPEAATWHWVDDHDGAA
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCEEEEECCCCCHH
QVLADLPDVILLTVGRQPVSHYLRLGPRRVIVRCVDAPEEELPAGWKVLRERGPFTLDRE
HHHHCCCCEEEEECCCCHHHHHHHCCCHHEEEEECCCCHHHCCHHHHHHHHCCCCCCCHH
REIFSQGVATLVSKDSGGTGLDPKLRLAAETDVQVVMVSRGPAPGWGDELSTVDDAVQWT
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHC
GNHIATVIEQ
CCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]