Click here to switch to the map view.

The map label for this gene is luxS

Identifier: 161621798

GI number: 161621798

Start: 495789

End: 496241

Strand: Reverse

Name: luxS

Synonym: PPA0450

Alternate gene names: 161621798

Gene position: 496241-495789 (Counterclockwise)

Preceding gene: 50841934

Following gene: 50841930

Centisome position: 19.38

GC content: 60.04

Gene sequence:

>453_bases
ATGAACGTCGAGAGTTTCAACCTGGACCACACCAAGGTGGCAGCACCATTCGTGCGTGTGGCCGACGTCAAGCACCTACC
CGCTGGCGACACCCTCACCAAGTACGACGTGAGGTTCTGCCAGCCCAACAAGGAACATCTGGACATGCCTGCGGTGCACT
CCCTGGAGCACTCCTTCGCCGAGTGCGTGCGAAACCACTCCGACGCCGTCATCGACTTCGGGCCGATGGGATGCCAGACC
GGGTTCTACCTCATCATGATCGGAGAACCAGATGTCTCAGGCACATGCGAACTCGTCGAGACCACCCTGCGCGACATCCT
CAAGCTCAACACCACCCCCGCCGCTAACGAAGTACAGTGCGGGTGGGGAGCCAACCATTCCATCAAGGCCGCCCAAGAAG
CCGCACACACGATGCTGAACCACCGCGACGAATGGGAACAGGTAATGGCCTGA

Upstream 100 bases:

>100_bases
TGCGACGGATTTATTGCTGCCGCCGGGCTTTAACCACAGCTGGCTGGTTGCCCGTGTGGGATTCGTGTCGATGCGAGAGG
ATGGGTTCATGGCACACAAA

Downstream 100 bases:

>100_bases
GGATTCGGCTACCACACCGAGCTCGTCAAGACACACCGCTTGCATCGTCTACCGCCCTCAACTACGAAGATATCGGGTTG
TGTTCGCCACAGCAGTAGAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNVESFNLDHTKVAAPFVRVADVKHLPAGDTLTKYDVRFCQPNKEHLDMPAVHSLEHSFAECVRNHSDAVIDFGPMGCQT
GFYLIMIGEPDVSGTCELVETTLRDILKLNTTPAANEVQCGWGANHSIKAAQEAAHTMLNHRDEWEQVMA

Sequences:

>Translated_150_residues
MNVESFNLDHTKVAAPFVRVADVKHLPAGDTLTKYDVRFCQPNKEHLDMPAVHSLEHSFAECVRNHSDAVIDFGPMGCQT
GFYLIMIGEPDVSGTCELVETTLRDILKLNTTPAANEVQCGWGANHSIKAAQEAAHTMLNHRDEWEQVMA
>Mature_150_residues
MNVESFNLDHTKVAAPFVRVADVKHLPAGDTLTKYDVRFCQPNKEHLDMPAVHSLEHSFAECVRNHSDAVIDFGPMGCQT
GFYLIMIGEPDVSGTCELVETTLRDILKLNTTPAANEVQCGWGANHSIKAAQEAAHTMLNHRDEWEQVMA

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=144, Percent_Identity=42.3611111111111, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_PROAC (Q6AAL4)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055160.2
- ProteinModelPortal:   Q6AAL4
- SMR:   Q6AAL4
- GeneID:   2932141
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0450
- NMPDR:   fig|267747.1.peg.437
- HOGENOM:   HBG347473
- OMA:   DKYSCGN
- ProtClustDB:   PRK02260
- BioCyc:   PACN267747:PPA0450-MONOMER
- BRENDA:   4.4.1.21
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 16647; Mature: 16647

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVESFNLDHTKVAAPFVRVADVKHLPAGDTLTKYDVRFCQPNKEHLDMPAVHSLEHSFA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECEEEECCCCHHHCCCCHHHHHHHHHH
ECVRNHSDAVIDFGPMGCQTGFYLIMIGEPDVSGTCELVETTLRDILKLNTTPAANEVQC
HHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEC
GWGANHSIKAAQEAAHTMLNHRDEWEQVMA
CCCCCCCHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MNVESFNLDHTKVAAPFVRVADVKHLPAGDTLTKYDVRFCQPNKEHLDMPAVHSLEHSFA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECEEEECCCCHHHCCCCHHHHHHHHHH
ECVRNHSDAVIDFGPMGCQTGFYLIMIGEPDVSGTCELVETTLRDILKLNTTPAANEVQC
HHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEC
GWGANHSIKAAQEAAHTMLNHRDEWEQVMA
CCCCCCCHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA