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The map label for this gene is treC [H]

Identifier: 50365316

GI number: 50365316

Start: 584838

End: 586457

Strand: Reverse

Name: treC [H]

Synonym: Mfl499

Alternate gene names: 50365316

Gene position: 586457-584838 (Counterclockwise)

Preceding gene: 50365317

Following gene: 50365315

Centisome position: 73.93

GC content: 24.44

Gene sequence:

>1620_bases
ATGAGAAATGAAGTAATTTATCAGATATTCCCTTTAACTTTTTCTGATGGTAAGAAAAAAGGTAAAGGAAATATCAAAGG
TATAATAAATAAATTAGATTATTTAAAAAGTTTAGGCATAACTAGAATATGAATATCTCCCTTTACAAAATCACCTTTTA
AAGATAGTGGTTATGATGTTTCAGATTATTGTGGAATAAATGAAGAATTTGGTACTATGGAAGAAGTGGAAATTCTTATA
TCTGAAGCAAAGAAAAGAGATTTAACAATTGTTTTAGATATAGTTTTCAATCATACTTCTGACCAACACGAATGATTTAA
AAAAGCTTTAGCTGGTGATGAAAAATATATGAATTATTATATTTTTAAAGATCCAGTCGATGGTAAAGAGCCAACTAATT
GAAAAAGTAAAATGGGTGGTTTAAGTTGAGAATTTGTACCTAATCTAAATAAATACTATTTACATTTATTTACAAAAGAA
CAACCAGATTTAAATTGAGAAAATCCAGAAGTTAGAAATGAACTAATTAATATATTAAAGTTTTGAAAAGATAAAGGTAT
TAGTGGTTTCAGACTTGATGTTTGTAATCTTTATAGCAAACCCACATTATTTGAAAATGATGAAATTGGGGATGGGCGAA
GATTCTATACAGATGGAGTAAAAGTTGAAGAGTATTTTAACTTGATGCATAATGAAGTTTTTGGAACTGATAATGAAATA
TTTACAGTTGGTGAAGTTTCATCAACAACTAAAGAAAAATCAGCTAAATATGCTAAGGTAGAAAATAAAGAGCTTGATTC
AGTTTTTACATTCTTACATCTAAAAGTTGATTATGAAAATAATGACAAATGAACAAATGTTAAACCTGATTTAAACTTGT
TTTGAAAATTACAAAAAGAATGACAAGAATATTATCAATTAGAAAATTCTACTTTAGCTTTATTTATGAATAATCATGAT
CAACCAAGAGCTGTTTCAAGATTTGGAAATGTAGATAAATATTGATATGAAAGTGCAACTTCTATTTTTGCATTTACTTC
ATTAATGCGTGGAGTTCCATTCATTTATCAAGGCGAAGAAATTGGTATGACAAATTTAACTTTTAATAACCTTAATGAAT
TTAAAGATGTTGAATCAATTGGAAATGCTAATGATTTATTAAAAATAAAATCAGAAGAAGAAGTACTTGATATTTTAAGA
ATTAAATCAAGAGACAATGCAAGAAGTGTGATGCAATGAAATGATGAATTCAATGCTGGATTTTCAGAAAAAGAAAATAT
AGATTTATTTGTTAATAAAAATTACAAAACAATCAATGTTAAAAACCAATTAAATGATGATAAATCTGTTTTAAATTTTT
ACAAAAAAGTAATTAATTTAAGATTAAATGAAGAAGTATTTAATGATGGAACAATTAGCTTTTTTGAAAATCAGGATTAT
GCATATTGTAGAAAATTAAAAGATAAAGAAATAATTATATTAACAAACTGAACAACTGAAAATAAATTGATAAAATTAAA
ACTAGATAGCAATAATTGAAAAATAATTTTAAATAATTATGAAGATTTTAGTTTTGATTCTTTAAAACCTTATCAAGTAA
TAGCAATCGAAAGGAAATAA

Upstream 100 bases:

>100_bases
TAAATATTTCGAAAAATTCAATATCGAAGTAAAAGCAGCAGAATTACTAAAATAATATTAAAATAATATTAAAATAAAAC
TAAATAGAAAAAGGGAAAAA

Downstream 100 bases:

>100_bases
AAACAATGAGATATAATGATCGTGAAAAGGCAAGATTTTCGCTTAATTCAAGTATTGCAGTTTTCATTGTTTCAACTTTA
CTTTTTATAATTAGTTGTAT

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MRNEVIYQIFPLTFSDGKKKGKGNIKGIINKLDYLKSLGITRIWISPFTKSPFKDSGYDVSDYCGINEEFGTMEEVEILI
SEAKKRDLTIVLDIVFNHTSDQHEWFKKALAGDEKYMNYYIFKDPVDGKEPTNWKSKMGGLSWEFVPNLNKYYLHLFTKE
QPDLNWENPEVRNELINILKFWKDKGISGFRLDVCNLYSKPTLFENDEIGDGRRFYTDGVKVEEYFNLMHNEVFGTDNEI
FTVGEVSSTTKEKSAKYAKVENKELDSVFTFLHLKVDYENNDKWTNVKPDLNLFWKLQKEWQEYYQLENSTLALFMNNHD
QPRAVSRFGNVDKYWYESATSIFAFTSLMRGVPFIYQGEEIGMTNLTFNNLNEFKDVESIGNANDLLKIKSEEEVLDILR
IKSRDNARSVMQWNDEFNAGFSEKENIDLFVNKNYKTINVKNQLNDDKSVLNFYKKVINLRLNEEVFNDGTISFFENQDY
AYCRKLKDKEIIILTNWTTENKLIKLKLDSNNWKIILNNYEDFSFDSLKPYQVIAIERK

Sequences:

>Translated_539_residues
MRNEVIYQIFPLTFSDGKKKGKGNIKGIINKLDYLKSLGITRI*ISPFTKSPFKDSGYDVSDYCGINEEFGTMEEVEILI
SEAKKRDLTIVLDIVFNHTSDQHE*FKKALAGDEKYMNYYIFKDPVDGKEPTN*KSKMGGLS*EFVPNLNKYYLHLFTKE
QPDLN*ENPEVRNELINILKF*KDKGISGFRLDVCNLYSKPTLFENDEIGDGRRFYTDGVKVEEYFNLMHNEVFGTDNEI
FTVGEVSSTTKEKSAKYAKVENKELDSVFTFLHLKVDYENNDK*TNVKPDLNLF*KLQKE*QEYYQLENSTLALFMNNHD
QPRAVSRFGNVDKY*YESATSIFAFTSLMRGVPFIYQGEEIGMTNLTFNNLNEFKDVESIGNANDLLKIKSEEEVLDILR
IKSRDNARSVMQ*NDEFNAGFSEKENIDLFVNKNYKTINVKNQLNDDKSVLNFYKKVINLRLNEEVFNDGTISFFENQDY
AYCRKLKDKEIIILTN*TTENKLIKLKLDSNN*KIILNNYEDFSFDSLKPYQVIAIERK
>Mature_539_residues
MRNEVIYQIFPLTFSDGKKKGKGNIKGIINKLDYLKSLGITRI*ISPFTKSPFKDSGYDVSDYCGINEEFGTMEEVEILI
SEAKKRDLTIVLDIVFNHTSDQHE*FKKALAGDEKYMNYYIFKDPVDGKEPTN*KSKMGGLS*EFVPNLNKYYLHLFTKE
QPDLN*ENPEVRNELINILKF*KDKGISGFRLDVCNLYSKPTLFENDEIGDGRRFYTDGVKVEEYFNLMHNEVFGTDNEI
FTVGEVSSTTKEKSAKYAKVENKELDSVFTFLHLKVDYENNDK*TNVKPDLNLF*KLQKE*QEYYQLENSTLALFMNNHD
QPRAVSRFGNVDKY*YESATSIFAFTSLMRGVPFIYQGEEIGMTNLTFNNLNEFKDVESIGNANDLLKIKSEEEVLDILR
IKSRDNARSVMQ*NDEFNAGFSEKENIDLFVNKNYKTINVKNQLNDDKSVLNFYKKVINLRLNEEVFNDGTISFFENQDY
AYCRKLKDKEIIILTN*TTENKLIKLKLDSNN*KIILNNYEDFSFDSLKPYQVIAIERK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=527, Percent_Identity=30.550284629981, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1790687, Length=546, Percent_Identity=40.1098901098901, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI32565753, Length=381, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322245, Length=487, Percent_Identity=31.6221765913758, Blast_Score=222, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6321726, Length=488, Percent_Identity=31.5573770491803, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6324416, Length=489, Percent_Identity=31.4928425357873, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6322241, Length=489, Percent_Identity=31.4928425357873, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6322021, Length=489, Percent_Identity=31.4928425357873, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6321731, Length=572, Percent_Identity=29.5454545454545, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319776, Length=572, Percent_Identity=29.3706293706294, Blast_Score=196, Evalue=5e-51,
Organism=Drosophila melanogaster, GI221330053, Length=486, Percent_Identity=32.3045267489712, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24586599, Length=525, Percent_Identity=30.6666666666667, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24583747, Length=482, Percent_Identity=32.7800829875519, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24583749, Length=482, Percent_Identity=32.7800829875519, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24586589, Length=495, Percent_Identity=32.1212121212121, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24583745, Length=520, Percent_Identity=28.4615384615385, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24586591, Length=485, Percent_Identity=32.3711340206186, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24586593, Length=502, Percent_Identity=29.8804780876494, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24586587, Length=529, Percent_Identity=27.2211720226843, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24586597, Length=217, Percent_Identity=37.7880184331797, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI45549022, Length=210, Percent_Identity=40.9523809523809, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281360393, Length=450, Percent_Identity=28.4444444444444, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 60840; Mature: 60840

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNEVIYQIFPLTFSDGKKKGKGNIKGIINKLDYLKSLGITRIISPFTKSPFKDSGYDVS
CCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHH
DYCGINEEFGTMEEVEILISEAKKRDLTIVLDIVFNHTSDQHEFKKALAGDEKYMNYYIF
HHCCCCHHHCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHCCCCHHEEEEEE
KDPVDGKEPTNKSKMGGLSEFVPNLNKYYLHLFTKEQPDLNENPEVRNELINILKFKDKG
ECCCCCCCCCCHHHCCCHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
ISGFRLDVCNLYSKPTLFENDEIGDGRRFYTDGVKVEEYFNLMHNEVFGTDNEIFTVGEV
CCCEEEEHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCC
SSTTKEKSAKYAKVENKELDSVFTFLHLKVDYENNDKTNVKPDLNLFKLQKEQEYYQLEN
CCHHHHHCCHHHHCCCCHHHHEEEEEEEEEEECCCCCCCCCCCCHHEEEHHHHHHHEECC
STLALFMNNHDQPRAVSRFGNVDKYYESATSIFAFTSLMRGVPFIYQGEEIGMTNLTFNN
CEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCC
LNEFKDVESIGNANDLLKIKSEEEVLDILRIKSRDNARSVMQNDEFNAGFSEKENIDLFV
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCEEEEE
NKNYKTINVKNQLNDDKSVLNFYKKVINLRLNEEVFNDGTISFFENQDYAYCRKLKDKEI
ECCEEEEEECCCCCCHHHHHHHHHHHHCEEECHHHCCCCCEEEEECCCHHHHHHCCCCEE
IILTNTTENKLIKLKLDSNNKIILNNYEDFSFDSLKPYQVIAIERK
EEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRNEVIYQIFPLTFSDGKKKGKGNIKGIINKLDYLKSLGITRIISPFTKSPFKDSGYDVS
CCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHH
DYCGINEEFGTMEEVEILISEAKKRDLTIVLDIVFNHTSDQHEFKKALAGDEKYMNYYIF
HHCCCCHHHCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHCCCCHHEEEEEE
KDPVDGKEPTNKSKMGGLSEFVPNLNKYYLHLFTKEQPDLNENPEVRNELINILKFKDKG
ECCCCCCCCCCHHHCCCHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
ISGFRLDVCNLYSKPTLFENDEIGDGRRFYTDGVKVEEYFNLMHNEVFGTDNEIFTVGEV
CCCEEEEHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCC
SSTTKEKSAKYAKVENKELDSVFTFLHLKVDYENNDKTNVKPDLNLFKLQKEQEYYQLEN
CCHHHHHCCHHHHCCCCHHHHEEEEEEEEEEECCCCCCCCCCCCHHEEEHHHHHHHEECC
STLALFMNNHDQPRAVSRFGNVDKYYESATSIFAFTSLMRGVPFIYQGEEIGMTNLTFNN
CEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCC
LNEFKDVESIGNANDLLKIKSEEEVLDILRIKSRDNARSVMQNDEFNAGFSEKENIDLFV
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCEEEEE
NKNYKTINVKNQLNDDKSVLNFYKKVINLRLNEEVFNDGTISFFENQDYAYCRKLKDKEI
ECCEEEEEECCCCCCHHHHHHHHHHHHCEEECHHHCCCCCEEEEECCCHHHHHHCCCCEE
IILTNTTENKLIKLKLDSNNKIILNNYEDFSFDSLKPYQVIAIERK
EEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]