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The map label for this gene is ruvA [H]

Identifier: 50365239

GI number: 50365239

Start: 492940

End: 493488

Strand: Reverse

Name: ruvA [H]

Synonym: Mfl421

Alternate gene names: 50365239

Gene position: 493488-492940 (Counterclockwise)

Preceding gene: 50365240

Following gene: 50365238

Centisome position: 62.21

GC content: 21.68

Gene sequence:

>549_bases
ATGAAGGATTATTTAGTTTGTGATATTAATTCAAAGGATGATAATTATTTATATGTTGAGTATCAGAATAAAGGAGAATA
CTTTTCTTATTTAACAAAAGATAATTTTAAAAATGAAAAAAACATTAAATTGTTTATTGTTGATCATAATACTGAATTTG
AAAATGTTGAAATAGTTTTCAGATCAAGAGATGAAAGAAACCTTTTTAAAGAATTGGTGAAAATTAAAACAGTAGGACTT
AAAACTTCTTTTTATTTATTAAATAATTTTTCATTTGAAGAATTTATAAAAATGATTGAAGAATATGATATTGAGAAATT
AGCTAAATTAAAAGGGATTGGCAATTATACAGCTAAACTAATAATTGAAGAATTGCAAAAGCATTTTTTCAAAAACAAAA
TAACTCAGAAAAAAGAAAAAATAATAACATCACTTGTTAAGCTGGGATTTTCTTATAAAACAATAATGAAAAATATTGCT
AATGTTGATAATTTACTTTCAGTGGATGAAATAACCAAAATAGTTATGGAGCAAATTAGTTATGAGTAA

Upstream 100 bases:

>100_bases
CTTATATGAAGCAGGAAAAATTGAACATTAATATATAAAAATCATTTCAATTGAGATGATTTTTTTATTTTTTCTTTAAT
AACTATATGAGGTGAAAAGA

Downstream 100 bases:

>100_bases
TGATTTTAGACCTAGTAAGTGGAGTGAATACATAGGACAAGAAAAGGTCATTAAGAATTTAAAAATATGTATAGAATCAT
CAATCAAACAAAATAAAGTT

Product: holliday junction DNA helicase ruvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKDYLVCDINSKDDNYLYVEYQNKGEYFSYLTKDNFKNEKNIKLFIVDHNTEFENVEIVFRSRDERNLFKELVKIKTVGL
KTSFYLLNNFSFEEFIKMIEEYDIEKLAKLKGIGNYTAKLIIEELQKHFFKNKITQKKEKIITSLVKLGFSYKTIMKNIA
NVDNLLSVDEITKIVMEQISYE

Sequences:

>Translated_182_residues
MKDYLVCDINSKDDNYLYVEYQNKGEYFSYLTKDNFKNEKNIKLFIVDHNTEFENVEIVFRSRDERNLFKELVKIKTVGL
KTSFYLLNNFSFEEFIKMIEEYDIEKLAKLKGIGNYTAKLIIEELQKHFFKNKITQKKEKIITSLVKLGFSYKTIMKNIA
NVDNLLSVDEITKIVMEQISYE
>Mature_182_residues
MKDYLVCDINSKDDNYLYVEYQNKGEYFSYLTKDNFKNEKNIKLFIVDHNTEFENVEIVFRSRDERNLFKELVKIKTVGL
KTSFYLLNNFSFEEFIKMIEEYDIEKLAKLKGIGNYTAKLIIEELQKHFFKNKITQKKEKIITSLVKLGFSYKTIMKNIA
NVDNLLSVDEITKIVMEQISYE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: NA

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21728; Mature: 21728

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDYLVCDINSKDDNYLYVEYQNKGEYFSYLTKDNFKNEKNIKLFIVDHNTEFENVEIVF
CCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEE
RSRDERNLFKELVKIKTVGLKTSFYLLNNFSFEEFIKMIEEYDIEKLAKLKGIGNYTAKL
ECCCHHHHHHHHHHHHHHCCCEEEHEEECCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHH
IIEELQKHFFKNKITQKKEKIITSLVKLGFSYKTIMKNIANVDNLLSVDEITKIVMEQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YE
CC
>Mature Secondary Structure
MKDYLVCDINSKDDNYLYVEYQNKGEYFSYLTKDNFKNEKNIKLFIVDHNTEFENVEIVF
CCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEE
RSRDERNLFKELVKIKTVGLKTSFYLLNNFSFEEFIKMIEEYDIEKLAKLKGIGNYTAKL
ECCCHHHHHHHHHHHHHHCCCEEEHEEECCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHH
IIEELQKHFFKNKITQKKEKIITSLVKLGFSYKTIMKNIANVDNLLSVDEITKIVMEQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA