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The map label for this gene is xseA [H]

Identifier: 50365147

GI number: 50365147

Start: 388257

End: 389471

Strand: Reverse

Name: xseA [H]

Synonym: Mfl331

Alternate gene names: 50365147

Gene position: 389471-388257 (Counterclockwise)

Preceding gene: 50365148

Following gene: 50365146

Centisome position: 49.1

GC content: 26.75

Gene sequence:

>1215_bases
ATGGAAAACAAAATATTTTCAGTAGCTGAAATAAGTCAAATATTTAAAGAAGCTATTGAAGGTAGTAATTATTTTAAAAA
TATATATGTCAGAGGGGAAGTTGGCAATCTAACTTTTAACAAATCGGGACATGTATATTTTTCTTTAAAAGATAATCAAA
GCACAATAGCTGCAATGATATGAAAAAGTAATGCACACAAACTAACAAACTTAAATGTAAAAGAAGGAATGGAAATTACA
TGTTATGGTAGATTAACTTATTATGTTCCAAGTGGAAGAGTAAGTTTTGAAGCTGTTGATGTAAGTGTTGAAGGAAAAGG
TGATCTTCAAGAAATTTTTGAAGAACGTTTAAAAGAAATAACTGCTCTAGGTTGAACAGATGAATCAAGAAAAAAACCAA
TAAATAGATTTGCTAAAAATATTGGTTTAATAACAACTGATTCTGGTGCAGCTATTAAAGATTTAATAACAACATTAAAA
AGAAGAATGCCTTCTGTAAACATTTACTTGTTTCCAACAATGGTTCAAGGTGAAACTGCTAAGTTTGATATAGCAAATAA
AATACAACAAGCTAATTTATTTGAACCTAAGTTAGATATCTTAATTGTTGGTCGTGGTGGAGGAAGTTATGAAGACTTAT
GAACTTTTAATGAAATGAAAGTTTTAAAAGCCATAGTTGATTCATCAATTCCAGTAATTAGTGCTGTTGGTCATGAACCA
GATATAACACTAAGTGATTATGTTGCTGATCTAAGAGCAGCAACACCAACTGCAGCAGCTGAATTAGCTTCAATTAGTAC
AGAAGAACTATTAAAAGAATTAGCATATAATTATGAAAATCAAATTCGTTTATTTAAGAATGTTTATAACAACCAACAAT
TAAAAATTGAAGAATTTAAAAAACAAAATATTTTAAAGATTAATAATAAATATGACTTACAATCACTTGATTTAAATTAC
ATTGAAAAAAGTTTTATCAATAATATAAACAATATAATTAGCAGAAATGAAATGTTTATAGAAAACATAGAATCAAAAAC
AGCTCTATTAGACCCTAAAAAGCCATTAGACAAAGGATTTGGTTTAATTATGAGTAAAGATAAGCAAATTATTAATTCTG
TTGACAAAGTAGATATAAATCAAGAAATAAAACTTGTGTTAAAAGATGGTGAAATAGAAACTATCATAAAAGGAGTAAAA
AAACATGGAAAATAA

Upstream 100 bases:

>100_bases
CTGTAACAATTAATGAATTAGTTAATTTGGTGAAAGAAAACGAAGTTGATTTTGATTACAAGTTTGTAAATGCGTGTTTG
GATAAGGTTATTAAACTATA

Downstream 100 bases:

>100_bases
AACATACGATCAATTAATTATTGAATTAAAAGAAGAAACATTAAAATTATCATCAAGTGAAATATCAATGGAAGAAGCAA
TGAAGATATTTGAAGAAAAC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MENKIFSVAEISQIFKEAIEGSNYFKNIYVRGEVGNLTFNKSGHVYFSLKDNQSTIAAMIWKSNAHKLTNLNVKEGMEIT
CYGRLTYYVPSGRVSFEAVDVSVEGKGDLQEIFEERLKEITALGWTDESRKKPINRFAKNIGLITTDSGAAIKDLITTLK
RRMPSVNIYLFPTMVQGETAKFDIANKIQQANLFEPKLDILIVGRGGGSYEDLWTFNEMKVLKAIVDSSIPVISAVGHEP
DITLSDYVADLRAATPTAAAELASISTEELLKELAYNYENQIRLFKNVYNNQQLKIEEFKKQNILKINNKYDLQSLDLNY
IEKSFINNINNIISRNEMFIENIESKTALLDPKKPLDKGFGLIMSKDKQIINSVDKVDINQEIKLVLKDGEIETIIKGVK
KHGK

Sequences:

>Translated_404_residues
MENKIFSVAEISQIFKEAIEGSNYFKNIYVRGEVGNLTFNKSGHVYFSLKDNQSTIAAMI*KSNAHKLTNLNVKEGMEIT
CYGRLTYYVPSGRVSFEAVDVSVEGKGDLQEIFEERLKEITALG*TDESRKKPINRFAKNIGLITTDSGAAIKDLITTLK
RRMPSVNIYLFPTMVQGETAKFDIANKIQQANLFEPKLDILIVGRGGGSYEDL*TFNEMKVLKAIVDSSIPVISAVGHEP
DITLSDYVADLRAATPTAAAELASISTEELLKELAYNYENQIRLFKNVYNNQQLKIEEFKKQNILKINNKYDLQSLDLNY
IEKSFINNINNIISRNEMFIENIESKTALLDPKKPLDKGFGLIMSKDKQIINSVDKVDINQEIKLVLKDGEIETIIKGVK
KHGK
>Mature_404_residues
MENKIFSVAEISQIFKEAIEGSNYFKNIYVRGEVGNLTFNKSGHVYFSLKDNQSTIAAMI*KSNAHKLTNLNVKEGMEIT
CYGRLTYYVPSGRVSFEAVDVSVEGKGDLQEIFEERLKEITALG*TDESRKKPINRFAKNIGLITTDSGAAIKDLITTLK
RRMPSVNIYLFPTMVQGETAKFDIANKIQQANLFEPKLDILIVGRGGGSYEDL*TFNEMKVLKAIVDSSIPVISAVGHEP
DITLSDYVADLRAATPTAAAELASISTEELLKELAYNYENQIRLFKNVYNNQQLKIEEFKKQNILKINNKYDLQSLDLNY
IEKSFINNINNIISRNEMFIENIESKTALLDPKKPLDKGFGLIMSKDKQIINSVDKVDINQEIKLVLKDGEIETIIKGVK
KHGK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=443, Percent_Identity=30.4740406320542, Blast_Score=212, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45071; Mature: 45071

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKIFSVAEISQIFKEAIEGSNYFKNIYVRGEVGNLTFNKSGHVYFSLKDNQSTIAAMI
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCEEECCCCEEEEEEECCCHHHHHHH
KSNAHKLTNLNVKEGMEITCYGRLTYYVPSGRVSFEAVDVSVEGKGDLQEIFEERLKEIT
HCCCHHEECCCHHCCCEEEEEEEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHHHH
ALGTDESRKKPINRFAKNIGLITTDSGAAIKDLITTLKRRMPSVNIYLFPTMVQGETAKF
HCCCCHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEE
DIANKIQQANLFEPKLDILIVGRGGGSYEDLTFNEMKVLKAIVDSSIPVISAVGHEPDIT
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
LSDYVADLRAATPTAAAELASISTEELLKELAYNYENQIRLFKNVYNNQQLKIEEFKKQN
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHHHHCCCC
ILKINNKYDLQSLDLNYIEKSFINNINNIISRNEMFIENIESKTALLDPKKPLDKGFGLI
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCCCHHHCCCEE
MSKDKQIINSVDKVDINQEIKLVLKDGEIETIIKGVKKHGK
EECCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MENKIFSVAEISQIFKEAIEGSNYFKNIYVRGEVGNLTFNKSGHVYFSLKDNQSTIAAMI
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCEEECCCCEEEEEEECCCHHHHHHH
KSNAHKLTNLNVKEGMEITCYGRLTYYVPSGRVSFEAVDVSVEGKGDLQEIFEERLKEIT
HCCCHHEECCCHHCCCEEEEEEEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHHHH
ALGTDESRKKPINRFAKNIGLITTDSGAAIKDLITTLKRRMPSVNIYLFPTMVQGETAKF
HCCCCHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEE
DIANKIQQANLFEPKLDILIVGRGGGSYEDLTFNEMKVLKAIVDSSIPVISAVGHEPDIT
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
LSDYVADLRAATPTAAAELASISTEELLKELAYNYENQIRLFKNVYNNQQLKIEEFKKQN
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHHHHCCCC
ILKINNKYDLQSLDLNYIEKSFINNINNIISRNEMFIENIESKTALLDPKKPLDKGFGLI
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCCCHHHCCCEE
MSKDKQIINSVDKVDINQEIKLVLKDGEIETIIKGVKKHGK
EECCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA