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The map label for this gene is bglC [H]

Identifier: 50365129

GI number: 50365129

Start: 364183

End: 365592

Strand: Direct

Name: bglC [H]

Synonym: Mfl313

Alternate gene names: 50365129

Gene position: 364183-365592 (Clockwise)

Preceding gene: 50365128

Following gene: 50365130

Centisome position: 45.91

GC content: 25.96

Gene sequence:

>1410_bases
ATGGAAATTAAAAAACTTAAAAAATTTGATGATGATTTTTTGTGAGGCGCTTCAATTTCTGCTTTTCAGGCAGAAGGTGC
TTCAACAAAAGATGGTAAAGGTTTATCAATTCAAGATGTTAAAAAAATTAGTGAAAAATATTCTGATTTTTCAGTAGCTG
CGGATTTCTATAATAATTACAAAGAGGATATTGCTTTGCTTAAAGAAATGGGATTGTCATCTTTCAGATTTTCAATCTCT
TGAACCCGTATTATTCCTGATGGAGATGGTGAAATAAATAAAAAAGGAATTATTTTTTATCATAACTTAATAGATGAGTT
AAAGAAAAATGGGATTGAACCAATTGTTACAATATATCATTTTGACTTACCTTTTTCATTACAACAAAAAGGTGGCTGAA
GTAATCGTGATATGATAGTAAAAGCTTTCTTAAAATATTCAAAAGTGTTATTTAATGAATATGCTAAAAAAGTTAAGTAT
TGGCTAACAATAAATGAACAAAATGTCATGATAATGATAGGAAGCAAAATGAAGTTTTTAAATGGAGGAGATAAAAAATT
CAATCAAAATGAGCTTTATAATCAATCTCATAATATGTTTATTGCGCAAGCATTAGTTATGGAAGAGATGCATAATAATT
TTCCTAATTGTTTAATAGCACCTGCTTTAAACATTGTTTCAATTTATCCCAATTCAAATAAACCTCAAGATTACTTAGCA
GCAATGAATGCATCTGTTATGAGAAATTGATATTATTTAGATGCTATTGTTAGAGGCGAATATAACCCAATAATGTATAA
ATATTTAGAAGACAATAATTTTTTACCTGATTTTAGAAAAGGTGATTATGAAATTCTAAAAAAAGCTAAGCCTGATTTTA
TAGCGTTTAACTATTATACTTCTGCAACAGTAAAAAGTGAAATTAATAATTTTATTGAAGTTGAAGAATTAATTGATCAA
CAAAGATTATTTGATGTGCCTGGTATGTTTAGTTATTGTGAAAATCCAAATTTAGAAAAAACTGAATATGGTTGAGATAT
TGATTCAACTGGTTTTAGGGTAACAATGAGGGAAATGTATGAAAGATATAGACTACCTTTAATGATTACTGAAAATGGAT
TAGGACATTCAGAGCAATTAAACGAAAATAATACTGTAGATGATGATTATAGAATTCAATATTATGAAAAACATTTAAAT
GAATTAAGAAAATGTATTTCAGAAGGAATAAAAATTATCTCATATAATGCTTGAACAGCTATTGATATTGTTTCATCTCA
TCAAGGTTTTTCAAAAAGATACGGTTTTATTTATGTTGATAGAACAGAAAAAGATTTGAAGGAAATGAAAAGATATCCCA
AAAAAAGTTTTTATTGATATAAAGAATATATTAAAAAAATAAAATATTAA

Upstream 100 bases:

>100_bases
CAATTGATATAAATTACTTAATAACTGAAAAACAAGAAACATTTTTTAATCAAAAAAATGTTAAAAAAAATCTTTTAAAT
AATAGATAGAGAGAATAAAT

Downstream 100 bases:

>100_bases
TTTTTTAATTCTAATTTTAAGTGTAGTACTTATGGCATGATTTCCTAAGTACTACATTTTTGTTTAAAAGTATGAGAAAA
TTAACAAAACATGGAGAACA

Product: beta-glucosidase/alpha xylosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MEIKKLKKFDDDFLWGASISAFQAEGASTKDGKGLSIQDVKKISEKYSDFSVAADFYNNYKEDIALLKEMGLSSFRFSIS
WTRIIPDGDGEINKKGIIFYHNLIDELKKNGIEPIVTIYHFDLPFSLQQKGGWSNRDMIVKAFLKYSKVLFNEYAKKVKY
WLTINEQNVMIMIGSKMKFLNGGDKKFNQNELYNQSHNMFIAQALVMEEMHNNFPNCLIAPALNIVSIYPNSNKPQDYLA
AMNASVMRNWYYLDAIVRGEYNPIMYKYLEDNNFLPDFRKGDYEILKKAKPDFIAFNYYTSATVKSEINNFIEVEELIDQ
QRLFDVPGMFSYCENPNLEKTEYGWDIDSTGFRVTMREMYERYRLPLMITENGLGHSEQLNENNTVDDDYRIQYYEKHLN
ELRKCISEGIKIISYNAWTAIDIVSSHQGFSKRYGFIYVDRTEKDLKEMKRYPKKSFYWYKEYIKKIKY

Sequences:

>Translated_469_residues
MEIKKLKKFDDDFL*GASISAFQAEGASTKDGKGLSIQDVKKISEKYSDFSVAADFYNNYKEDIALLKEMGLSSFRFSIS
*TRIIPDGDGEINKKGIIFYHNLIDELKKNGIEPIVTIYHFDLPFSLQQKGG*SNRDMIVKAFLKYSKVLFNEYAKKVKY
WLTINEQNVMIMIGSKMKFLNGGDKKFNQNELYNQSHNMFIAQALVMEEMHNNFPNCLIAPALNIVSIYPNSNKPQDYLA
AMNASVMRN*YYLDAIVRGEYNPIMYKYLEDNNFLPDFRKGDYEILKKAKPDFIAFNYYTSATVKSEINNFIEVEELIDQ
QRLFDVPGMFSYCENPNLEKTEYG*DIDSTGFRVTMREMYERYRLPLMITENGLGHSEQLNENNTVDDDYRIQYYEKHLN
ELRKCISEGIKIISYNA*TAIDIVSSHQGFSKRYGFIYVDRTEKDLKEMKRYPKKSFY*YKEYIKKIKY
>Mature_469_residues
MEIKKLKKFDDDFL*GASISAFQAEGASTKDGKGLSIQDVKKISEKYSDFSVAADFYNNYKEDIALLKEMGLSSFRFSIS
*TRIIPDGDGEINKKGIIFYHNLIDELKKNGIEPIVTIYHFDLPFSLQQKGG*SNRDMIVKAFLKYSKVLFNEYAKKVKY
WLTINEQNVMIMIGSKMKFLNGGDKKFNQNELYNQSHNMFIAQALVMEEMHNNFPNCLIAPALNIVSIYPNSNKPQDYLA
AMNASVMRN*YYLDAIVRGEYNPIMYKYLEDNNFLPDFRKGDYEILKKAKPDFIAFNYYTSATVKSEINNFIEVEELIDQ
QRLFDVPGMFSYCENPNLEKTEYG*DIDSTGFRVTMREMYERYRLPLMITENGLGHSEQLNENNTVDDDYRIQYYEKHLN
ELRKCISEGIKIISYNA*TAIDIVSSHQGFSKRYGFIYVDRTEKDLKEMKRYPKKSFY*YKEYIKKIKY

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=474, Percent_Identity=28.9029535864979, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI32481206, Length=475, Percent_Identity=30.7368421052632, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI110681710, Length=485, Percent_Identity=29.4845360824742, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI24497614, Length=487, Percent_Identity=27.3100616016427, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI28376633, Length=462, Percent_Identity=27.7056277056277, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI2367270, Length=472, Percent_Identity=35.5932203389831, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI2367174, Length=484, Percent_Identity=34.0909090909091, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789070, Length=479, Percent_Identity=35.0730688935282, Blast_Score=262, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17552856, Length=477, Percent_Identity=29.3501048218029, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17539390, Length=481, Percent_Identity=30.1455301455301, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21356577, Length=468, Percent_Identity=26.4957264957265, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53858; Mature: 53858

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKKLKKFDDDFLGASISAFQAEGASTKDGKGLSIQDVKKISEKYSDFSVAADFYNNYK
CCCHHHHHCCHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
EDIALLKEMGLSSFRFSISTRIIPDGDGEINKKGIIFYHNLIDELKKNGIEPIVTIYHFD
HHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEEEEEC
LPFSLQQKGGSNRDMIVKAFLKYSKVLFNEYAKKVKYWLTINEQNVMIMIGSKMKFLNGG
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECCCEEECCCC
DKKFNQNELYNQSHNMFIAQALVMEEMHNNFPNCLIAPALNIVSIYPNSNKPQDYLAAMN
CCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCHHHHHHHH
ASVMRNYYLDAIVRGEYNPIMYKYLEDNNFLPDFRKGDYEILKKAKPDFIAFNYYTSATV
HHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCEEEEEEEECHHH
KSEINNFIEVEELIDQQRLFDVPGMFSYCENPNLEKTEYGDIDSTGFRVTMREMYERYRL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCC
PLMITENGLGHSEQLNENNTVDDDYRIQYYEKHLNELRKCISEGIKIISYNATAIDIVSS
CEEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECC
HQGFSKRYGFIYVDRTEKDLKEMKRYPKKSFYYKEYIKKIKY
CCCHHHCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEIKKLKKFDDDFLGASISAFQAEGASTKDGKGLSIQDVKKISEKYSDFSVAADFYNNYK
CCCHHHHHCCHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
EDIALLKEMGLSSFRFSISTRIIPDGDGEINKKGIIFYHNLIDELKKNGIEPIVTIYHFD
HHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEEEEEC
LPFSLQQKGGSNRDMIVKAFLKYSKVLFNEYAKKVKYWLTINEQNVMIMIGSKMKFLNGG
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECCCEEECCCC
DKKFNQNELYNQSHNMFIAQALVMEEMHNNFPNCLIAPALNIVSIYPNSNKPQDYLAAMN
CCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCHHHHHHHH
ASVMRNYYLDAIVRGEYNPIMYKYLEDNNFLPDFRKGDYEILKKAKPDFIAFNYYTSATV
HHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCEEEEEEEECHHH
KSEINNFIEVEELIDQQRLFDVPGMFSYCENPNLEKTEYGDIDSTGFRVTMREMYERYRL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCC
PLMITENGLGHSEQLNENNTVDDDYRIQYYEKHLNELRKCISEGIKIISYNATAIDIVSS
CEEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECC
HQGFSKRYGFIYVDRTEKDLKEMKRYPKKSFYYKEYIKKIKY
CCCHHHCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]