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The map label for this gene is fruK [H]

Identifier: 50364996

GI number: 50364996

Start: 209217

End: 210152

Strand: Direct

Name: fruK [H]

Synonym: Mfl180

Alternate gene names: 50364996

Gene position: 209217-210152 (Clockwise)

Preceding gene: 50364995

Following gene: 50364997

Centisome position: 26.38

GC content: 25.0

Gene sequence:

>936_bases
ATGATATATACAGTAACACTAAATCCTGCTCTAGATCATATTATTGAAACTGATGGATTTAATATTGGTGAAACTAATTA
TTACAAAAATGAATATGTTGTAATTGGTGGAAAAGGTATTAATGTTTCTATTATTTTGAATAATTTAGAAGCAAAAGTTT
TATCTACTGGTATCTTGGGATCAAATAATAAAAATTCGTTTTTAGAAAAATTTGATGAAAACAATTTAAAAAACAAATTT
TTTATAAATAAAGGTGTAACAAGAACAAATTTGAAAATAAAAAACTTATCTAAGTTTGAAGAAACTGAATTAAATGGTTT
AGGTTCAACAGTAAGTTTAGAGATAATAAATGAATTAAAAACCTTTTTAAACGATAACTTAAAAAGCGGTGATATTTTAG
TTGCTGCAGGAAGTATACCAGCTGGTGTTAAAAATAATATTTATGAAGAAATAGGAAATATTGCAAATGAAAAGAATGCT
TTATTTATTTTAGACACATCAAAGGTAAACATGTTAAATGGTTTAAAAACAAAACCTTATTTAATAAAACCAAATATAGA
AGAAATATGTGAAATTTTAAATTTACCATTTAAAGAATATACTTTTGAAGAAACATGTGAAATGGTAAAAAAATTAAAAT
CATTAGGAGCTAGAAATGTTTTATTAAGCAGAGGAAGCAAAGGTAGTTATTTCTTTTCAGAAAAAGGAGAAATTTTTGAA
ACAGGAATAGCAAAAGGTAAATTAGTTAATTCAGTTGGATCTGGAGATAGTATGATTGCTGGATTCACATATGGATTATA
TAAAAATTTATCAATAGAAGAATGCCTTCAATTTGGAGCTGCAGCAGGTGGGGCAACTGCCTTTACCGAATGATTAGGAT
TAAAAGAAGACATTTTAAAATTAAAACAAGAAATTAAAGTTAACAAAATAAAATAG

Upstream 100 bases:

>100_bases
AGCTATGGTTTAGCTGACTCAAGCAAATTAGATAGAAAATCCTTCTATAAGTTCGCTGACAAAGAATCAATTAAATTAAT
ATAAAAAAAGAGGAAATAAA

Downstream 100 bases:

>100_bases
GAGATAAATATGGAATTAAAAGATTTATTTAAATCTAAAGTTTCAGTCTTCAAAGCAGATTTAAAAACAAAAGAAGAAGT
TATTAATTTTTTAGTTGATA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIYTVTLNPALDHIIETDGFNIGETNYYKNEYVVIGGKGINVSIILNNLEAKVLSTGILGSNNKNSFLEKFDENNLKNKF
FINKGVTRTNLKIKNLSKFEETELNGLGSTVSLEIINELKTFLNDNLKSGDILVAAGSIPAGVKNNIYEEIGNIANEKNA
LFILDTSKVNMLNGLKTKPYLIKPNIEEICEILNLPFKEYTFEETCEMVKKLKSLGARNVLLSRGSKGSYFFSEKGEIFE
TGIAKGKLVNSVGSGDSMIAGFTYGLYKNLSIEECLQFGAAAGGATAFTEWLGLKEDILKLKQEIKVNKIK

Sequences:

>Translated_311_residues
MIYTVTLNPALDHIIETDGFNIGETNYYKNEYVVIGGKGINVSIILNNLEAKVLSTGILGSNNKNSFLEKFDENNLKNKF
FINKGVTRTNLKIKNLSKFEETELNGLGSTVSLEIINELKTFLNDNLKSGDILVAAGSIPAGVKNNIYEEIGNIANEKNA
LFILDTSKVNMLNGLKTKPYLIKPNIEEICEILNLPFKEYTFEETCEMVKKLKSLGARNVLLSRGSKGSYFFSEKGEIFE
TGIAKGKLVNSVGSGDSMIAGFTYGLYKNLSIEECLQFGAAAGGATAFTE*LGLKEDILKLKQEIKVNKIK
>Mature_311_residues
MIYTVTLNPALDHIIETDGFNIGETNYYKNEYVVIGGKGINVSIILNNLEAKVLSTGILGSNNKNSFLEKFDENNLKNKF
FINKGVTRTNLKIKNLSKFEETELNGLGSTVSLEIINELKTFLNDNLKSGDILVAAGSIPAGVKNNIYEEIGNIANEKNA
LFILDTSKVNMLNGLKTKPYLIKPNIEEICEILNLPFKEYTFEETCEMVKKLKSLGARNVLLSRGSKGSYFFSEKGEIFE
TGIAKGKLVNSVGSGDSMIAGFTYGLYKNLSIEECLQFGAAAGGATAFTE*LGLKEDILKLKQEIKVNKIK

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=285, Percent_Identity=31.5789473684211, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788017, Length=305, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 34108; Mature: 34108

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTVTLNPALDHIIETDGFNIGETNYYKNEYVVIGGKGINVSIILNNLEAKVLSTGILG
CEEEEEECHHHHHHHHCCCCCCCCCCEECCEEEEEECCCCEEEEEEECCHHHHHHHCCCC
SNNKNSFLEKFDENNLKNKFFINKGVTRTNLKIKNLSKFEETELNGLGSTVSLEIINELK
CCCCHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHCCCCCEEHHHHHHHHH
TFLNDNLKSGDILVAAGSIPAGVKNNIYEEIGNIANEKNALFILDTSKVNMLNGLKTKPY
HHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCE
LIKPNIEEICEILNLPFKEYTFEETCEMVKKLKSLGARNVLLSRGSKGSYFFSEKGEIFE
EECCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEECCCCCCHH
TGIAKGKLVNSVGSGDSMIAGFTYGLYKNLSIEECLQFGAAAGGATAFTELGLKEDILKL
HCCCCCHHHHCCCCCCCEEEHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHCCCHHHHHHH
KQEIKVNKIK
HHHHCCCCCC
>Mature Secondary Structure
MIYTVTLNPALDHIIETDGFNIGETNYYKNEYVVIGGKGINVSIILNNLEAKVLSTGILG
CEEEEEECHHHHHHHHCCCCCCCCCCEECCEEEEEECCCCEEEEEEECCHHHHHHHCCCC
SNNKNSFLEKFDENNLKNKFFINKGVTRTNLKIKNLSKFEETELNGLGSTVSLEIINELK
CCCCHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHCCCCCEEHHHHHHHHH
TFLNDNLKSGDILVAAGSIPAGVKNNIYEEIGNIANEKNALFILDTSKVNMLNGLKTKPY
HHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCE
LIKPNIEEICEILNLPFKEYTFEETCEMVKKLKSLGARNVLLSRGSKGSYFFSEKGEIFE
EECCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEECCCCCCHH
TGIAKGKLVNSVGSGDSMIAGFTYGLYKNLSIEECLQFGAAAGGATAFTELGLKEDILKL
HCCCCCHHHHCCCCCCCEEEHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHCCCHHHHHHH
KQEIKVNKIK
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]