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The map label for this gene is fruR [H]

Identifier: 50364995

GI number: 50364995

Start: 208508

End: 209200

Strand: Direct

Name: fruR [H]

Synonym: Mfl179

Alternate gene names: 50364995

Gene position: 208508-209200 (Clockwise)

Preceding gene: 50364994

Following gene: 50364996

Centisome position: 26.29

GC content: 27.56

Gene sequence:

>693_bases
ATGATTAAAAAACAAAGACAATCAATAATTTTAAATTTTTTAAAGGGTAAAAAAATTGTTGCTATTGAAACCCTTTCGAA
TGAATTAAAGATTCCACTTACAACGTTAAGAAGAGACTTAGCAGAACTTGAAGAACTAAAAAAGATAGTAAAGTTACATG
GTGGAGTTGAGTACAAGGAACCCGCATTCATCTATGAAGATTTTTTTGAAAAGAAAATTAAAGATAATGTTAAGGAAAAA
GAAACAATTGCCAAGGAAGCAATAAAAAAAATCAAAAAGAACGATTCAATTTTTATTGATTCAGGTTCAAATGGTTATTT
TATTGCTAAAAATTTAAAAGCTGACCTAAATCTACAAATAGTAACAAACTCAATTTACAATATTTTGGAACTTGTAAAAA
ATGGTCACGACAATGTTTACTTACTTGGTGGTAAGTTTACTAATGTAACGGGAGCTATTTTAGGATTTGAAGCTTTAGAA
GCTTTAAAAAATTATAATTTTGATATTGCATTTTTGGGTGTTAATGCTGTTGATGAAAATGGAAACATATATACAACAAG
TCCAGAGCATGCACAAGTTAAAATCGAAGTTATTAAAAATTCAAGAGAAAGCTATGGTTTAGCTGACTCAAGCAAATTAG
ATAGAAAATCCTTCTATAAGTTCGCTGACAAAGAATCAATTAAATTAATATAA

Upstream 100 bases:

>100_bases
CATCATTTTAGATATAATTAATAAAAATAAAAAAAACAAATCAAAACTTTTGGTTTTTTTTTGGTTTTTTTTGGTAATAT
GAAATTAGAAAGGGAAATCT

Downstream 100 bases:

>100_bases
AAAAAGAGGAAATAAAATGATATATACAGTAACACTAAATCCTGCTCTAGATCATATTATTGAAACTGATGGATTTAATA
TTGGTGAAACTAATTATTAC

Product: fru repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIKKQRQSIILNFLKGKKIVAIETLSNELKIPLTTLRRDLAELEELKKIVKLHGGVEYKEPAFIYEDFFEKKIKDNVKEK
ETIAKEAIKKIKKNDSIFIDSGSNGYFIAKNLKADLNLQIVTNSIYNILELVKNGHDNVYLLGGKFTNVTGAILGFEALE
ALKNYNFDIAFLGVNAVDENGNIYTTSPEHAQVKIEVIKNSRESYGLADSSKLDRKSFYKFADKESIKLI

Sequences:

>Translated_230_residues
MIKKQRQSIILNFLKGKKIVAIETLSNELKIPLTTLRRDLAELEELKKIVKLHGGVEYKEPAFIYEDFFEKKIKDNVKEK
ETIAKEAIKKIKKNDSIFIDSGSNGYFIAKNLKADLNLQIVTNSIYNILELVKNGHDNVYLLGGKFTNVTGAILGFEALE
ALKNYNFDIAFLGVNAVDENGNIYTTSPEHAQVKIEVIKNSRESYGLADSSKLDRKSFYKFADKESIKLI
>Mature_230_residues
MIKKQRQSIILNFLKGKKIVAIETLSNELKIPLTTLRRDLAELEELKKIVKLHGGVEYKEPAFIYEDFFEKKIKDNVKEK
ETIAKEAIKKIKKNDSIFIDSGSNGYFIAKNLKADLNLQIVTNSIYNILELVKNGHDNVYLLGGKFTNVTGAILGFEALE
ALKNYNFDIAFLGVNAVDENGNIYTTSPEHAQVKIEVIKNSRESYGLADSSKLDRKSFYKFADKESIKLI

Specific function: Repressor Of The Glycerol-3-Phosphate Regulon. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=222, Percent_Identity=27.4774774774775, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1789059, Length=237, Percent_Identity=30.8016877637131, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789170, Length=220, Percent_Identity=28.6363636363636, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=26.6375545851528, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI226510968, Length=220, Percent_Identity=26.3636363636364, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=26.9565217391304, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787540, Length=221, Percent_Identity=25.3393665158371, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87082344, Length=207, Percent_Identity=25.1207729468599, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790753, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790635, Length=149, Percent_Identity=28.1879194630872, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26083; Mature: 26083

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKQRQSIILNFLKGKKIVAIETLSNELKIPLTTLRRDLAELEELKKIVKLHGGVEYKE
CCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PAFIYEDFFEKKIKDNVKEKETIAKEAIKKIKKNDSIFIDSGSNGYFIAKNLKADLNLQI
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCEEEEE
VTNSIYNILELVKNGHDNVYLLGGKFTNVTGAILGFEALEALKNYNFDIAFLGVNAVDEN
EHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECC
GNIYTTSPEHAQVKIEVIKNSRESYGLADSSKLDRKSFYKFADKESIKLI
CCEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHHHHCCCCCEECC
>Mature Secondary Structure
MIKKQRQSIILNFLKGKKIVAIETLSNELKIPLTTLRRDLAELEELKKIVKLHGGVEYKE
CCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PAFIYEDFFEKKIKDNVKEKETIAKEAIKKIKKNDSIFIDSGSNGYFIAKNLKADLNLQI
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCEEEEE
VTNSIYNILELVKNGHDNVYLLGGKFTNVTGAILGFEALEALKNYNFDIAFLGVNAVDEN
EHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECC
GNIYTTSPEHAQVKIEVIKNSRESYGLADSSKLDRKSFYKFADKESIKLI
CCEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]