Click here to switch to the map view.

The map label for this gene is msrB

Identifier: 50085207

GI number: 50085207

Start: 2068670

End: 2069089

Strand: Reverse

Name: msrB

Synonym: ACIAD2086

Alternate gene names: 50085207

Gene position: 2069089-2068670 (Counterclockwise)

Preceding gene: 50085215

Following gene: 50085206

Centisome position: 57.5

GC content: 40.71

Gene sequence:

>420_bases
ATGGGAAAGCTCAATAAAACAGAAAGAGAATGGCAAAGAGAGTTATCACCAGAAGAGTACCGAATCACTAGGCAGAAAGG
TACTGAACCTGCATTTACAGGACAATACTGGAATACTAAGCAATCAGGAACCTATGTATGTCGCTGTTGTGGCACTGAGT
TGTTCTCTTCAATCAGTAAATACGATAGTGGTTGCGGATGGCCAAGCTTTTACAAACCGATTAATACCACAGCAATAGAG
GAACACGATGATTTTTCACATGGAATGGTGAGAACAGAAATTGTTTGTCATCACTGTGATGCTCATTTAGGGCATGTTTT
TGAAGATGGACCGCAGCCGACGGGATTACGCTATTGTGTCAATTCGGCATCATTACAACTAAAAACCGATGAAAAGAATG
ATGAGGAAACTTATCCATGA

Upstream 100 bases:

>100_bases
GTTTTTGTAAATTGTGAATGAAACACTAGAAATTTTAGATTGAATGACGTAAATATAGGATTATCCTATTTTAAACAGCA
AAATAGACAGGGAAATCATT

Downstream 100 bases:

>100_bases
CTAACCTTTACCAATTTGAAGCTGAGCTATTAGAAGGTGATACAAAATCACTAGCCGATTATCAGGGGAAAGTACTTTTG
ATTGTCAATACAGCCAGCAA

Product: peptide methionine sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MGKLNKTEREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQSGTYVCRCCGTELFSSISKYDSGCGWPSFYKPINTTAIE
EHDDFSHGMVRTEIVCHHCDAHLGHVFEDGPQPTGLRYCVNSASLQLKTDEKNDEETYP

Sequences:

>Translated_139_residues
MGKLNKTEREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQSGTYVCRCCGTELFSSISKYDSGCGWPSFYKPINTTAIE
EHDDFSHGMVRTEIVCHHCDAHLGHVFEDGPQPTGLRYCVNSASLQLKTDEKNDEETYP
>Mature_138_residues
GKLNKTEREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQSGTYVCRCCGTELFSSISKYDSGCGWPSFYKPINTTAIEE
HDDFSHGMVRTEIVCHHCDAHLGHVFEDGPQPTGLRYCVNSASLQLKTDEKNDEETYP

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=52.8, Blast_Score=146, Evalue=6e-36,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=52.8, Blast_Score=146, Evalue=6e-36,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=52.8, Blast_Score=146, Evalue=6e-36,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=52.8, Blast_Score=145, Evalue=7e-36,
Organism=Homo sapiens, GI117606353, Length=133, Percent_Identity=50.3759398496241, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI1788077, Length=131, Percent_Identity=54.9618320610687, Blast_Score=149, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17553450, Length=127, Percent_Identity=49.6062992125984, Blast_Score=122, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=121, Percent_Identity=49.5867768595041, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=44.8818897637795, Blast_Score=107, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=46.031746031746, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=46.031746031746, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=46.031746031746, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378664, Length=126, Percent_Identity=46.031746031746, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378662, Length=133, Percent_Identity=43.609022556391, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=42.3357664233577, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=42.3357664233577, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_ACIAD (Q6FAL8)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046717.1
- HSSP:   P54155
- ProteinModelPortal:   Q6FAL8
- SMR:   Q6FAL8
- STRING:   Q6FAL8
- GeneID:   2879149
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2086
- NMPDR:   fig|62977.3.peg.1979
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   EVRCNHC
- PhylomeDB:   Q6FAL8
- ProtClustDB:   CLSK707445
- BioCyc:   ASP62977:ACIAD2086-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 15964; Mature: 15833

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLNKTEREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQSGTYVCRCCGTELFSSISK
CCCCCCHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
YDSGCGWPSFYKPINTTAIEEHDDFSHGMVRTEIVCHHCDAHLGHVFEDGPQPTGLRYCV
HCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
NSASLQLKTDEKNDEETYP
CCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GKLNKTEREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQSGTYVCRCCGTELFSSISK
CCCCCHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
YDSGCGWPSFYKPINTTAIEEHDDFSHGMVRTEIVCHHCDAHLGHVFEDGPQPTGLRYCV
HCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
NSASLQLKTDEKNDEETYP
CCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA