Click here to switch to the map view.

The map label for this gene is lytT

Identifier: 49188279

GI number: 49188279

Start: 5179873

End: 5180613

Strand: Reverse

Name: lytT

Synonym: BAS5295

Alternate gene names: 49188279

Gene position: 5180613-5179873 (Counterclockwise)

Preceding gene: 49188280

Following gene: 49188278

Centisome position: 99.08

GC content: 33.33

Gene sequence:

>741_bases
TTGTTAAAAGTATTAGTAGTTGATGATGAAATGTTAGCACGTGATGAACTAAAGTATTTATTAGAGAGAACGAAGGAAGT
TGAGATAATTGGTGAGGCTGATTGTGTAGAGGACGCATTAGAAGAGTTAATGAAAAACAAACCAGATATTGTTTTCCTAG
ATATTCAATTATCGGATGATAACGGATTCGAAATCGCGAATATATTAAAGAAGATGAAAAATCCACCTGCAATTGTATTT
GCGACTGCCTATGATCAATACGCGTTGCAAGCATTTGAAGTAGATGCGTTAGACTATATTTTAAAGCCATTTGATGAAGA
ACGTATTGTACAAACATTAAAGAAATATAAAAAACAAAAACAATCGCAAATAGAAATGAAGCAAGAAATAAAAGGGGCAG
ATGTAACGGCAGAGATGCATAAATTAGCATTACCAATTGAGGAATCGATTGTTCTTGTAAATATTGAAGATATTGTATAT
GTAGGGCTTGTGGACGGAAAAGTGACAGTAAAAACAGTGAGGGAAACATATGTAACACACGATACGCTTGTAATTTTGGA
AAAGAAGTTGCCACAAGCAAGTTTCATGCGTGTCCATCGTAGCTTTATTGCAAATATTAATCATATTACTGAAATTCAGC
CATGGTTCAACTCTACTTATAATTTAATTATGAAAGAAGGATCAAAAGTACCTGTTAGTCGTACATATGCAAAAGAACTC
AAGAAGCTGCTTCGTATTTAA

Upstream 100 bases:

>100_bases
TTATTTGGGAAGGAAACGATGCTTCATATCGAAAGTGAAGTAAATGAGGGGACAGAGATTACTTTTGTTATTCCAAAAAA
AGTAGGGGAGGAAGAGCAGA

Downstream 100 bases:

>100_bases
GAAGCAGCTTTTGTATTTCATCCTTTTATATTTGTAACTGATTCTGTATATTTGACGTTCCGTTATGTAAACGCTTACTA
TAGCGGTTATATCCTATACA

Product: response regulator LytR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLKVLVVDDEMLARDELKYLLERTKEVEIIGEADCVEDALEELMKNKPDIVFLDIQLSDDNGFEIANILKKMKNPPAIVF
ATAYDQYALQAFEVDALDYILKPFDEERIVQTLKKYKKQKQSQIEMKQEIKGADVTAEMHKLALPIEESIVLVNIEDIVY
VGLVDGKVTVKTVRETYVTHDTLVILEKKLPQASFMRVHRSFIANINHITEIQPWFNSTYNLIMKEGSKVPVSRTYAKEL
KKLLRI

Sequences:

>Translated_246_residues
MLKVLVVDDEMLARDELKYLLERTKEVEIIGEADCVEDALEELMKNKPDIVFLDIQLSDDNGFEIANILKKMKNPPAIVF
ATAYDQYALQAFEVDALDYILKPFDEERIVQTLKKYKKQKQSQIEMKQEIKGADVTAEMHKLALPIEESIVLVNIEDIVY
VGLVDGKVTVKTVRETYVTHDTLVILEKKLPQASFMRVHRSFIANINHITEIQPWFNSTYNLIMKEGSKVPVSRTYAKEL
KKLLRI
>Mature_246_residues
MLKVLVVDDEMLARDELKYLLERTKEVEIIGEADCVEDALEELMKNKPDIVFLDIQLSDDNGFEIANILKKMKNPPAIVF
ATAYDQYALQAFEVDALDYILKPFDEERIVQTLKKYKKQKQSQIEMKQEIKGADVTAEMHKLALPIEESIVLVNIEDIVY
VGLVDGKVTVKTVRETYVTHDTLVILEKKLPQASFMRVHRSFIANINHITEIQPWFNSTYNLIMKEGSKVPVSRTYAKEL
KKLLRI

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788724, Length=246, Percent_Identity=39.0243902439024, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87082052, Length=249, Percent_Identity=35.7429718875502, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788222, Length=133, Percent_Identity=26.3157894736842, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYTT_BACAN (Q81JL3)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847837.1
- RefSeq:   YP_022736.1
- RefSeq:   YP_031532.1
- ProteinModelPortal:   Q81JL3
- EnsemblBacteria:   EBBACT00000011578
- EnsemblBacteria:   EBBACT00000015077
- EnsemblBacteria:   EBBACT00000019590
- GeneID:   1085431
- GeneID:   2818679
- GeneID:   2853102
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5691
- KEGG:   bar:GBAA_5691
- KEGG:   bat:BAS5295
- TIGR:   BA_5691
- TIGR:   GBAA_5691
- GeneTree:   EBGT00050000000047
- HOGENOM:   HBG753323
- OMA:   IYVGLVD
- ProtClustDB:   CLSK887700
- BioCyc:   BANT260799:BAS5295-MONOMER
- BioCyc:   BANT261594:GBAA5691-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789
- SMART:   SM00850
- SMART:   SM00448

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 28375; Mature: 28375

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50930 HTH_LYTTR; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVLVVDDEMLARDELKYLLERTKEVEIIGEADCVEDALEELMKNKPDIVFLDIQLSDD
CEEEEEECCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGFEIANILKKMKNPPAIVFATAYDQYALQAFEVDALDYILKPFDEERIVQTLKKYKKQK
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QSQIEMKQEIKGADVTAEMHKLALPIEESIVLVNIEDIVYVGLVDGKVTVKTVRETYVTH
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEHHEEEEEEECCEEEEHHHHHHHHCC
DTLVILEKKLPQASFMRVHRSFIANINHITEIQPWFNSTYNLIMKEGSKVPVSRTYAKEL
HHEEEEEHHCCHHHHHHHHHHHHHCCHHHHCCCHHHCCHHHHHEECCCCCCCHHHHHHHH
KKLLRI
HHHHCC
>Mature Secondary Structure
MLKVLVVDDEMLARDELKYLLERTKEVEIIGEADCVEDALEELMKNKPDIVFLDIQLSDD
CEEEEEECCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGFEIANILKKMKNPPAIVFATAYDQYALQAFEVDALDYILKPFDEERIVQTLKKYKKQK
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QSQIEMKQEIKGADVTAEMHKLALPIEESIVLVNIEDIVYVGLVDGKVTVKTVRETYVTH
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEHHEEEEEEECCEEEEHHHHHHHHCC
DTLVILEKKLPQASFMRVHRSFIANINHITEIQPWFNSTYNLIMKEGSKVPVSRTYAKEL
HHEEEEEHHCCHHHHHHHHHHHHHCCHHHHCCCHHHCCHHHHHEECCCCCCCHHHHHHHH
KKLLRI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629