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The map label for this gene is ftsX [H]

Identifier: 49188019

GI number: 49188019

Start: 4905832

End: 4906725

Strand: Reverse

Name: ftsX [H]

Synonym: BAS5033

Alternate gene names: 49188019

Gene position: 4906725-4905832 (Counterclockwise)

Preceding gene: 49188020

Following gene: 49188018

Centisome position: 93.84

GC content: 35.01

Gene sequence:

>894_bases
ATGAAGGCTAAGACCCTTAGTCGACATTTGCGAGAAGGTGTGAAAAATCTATCCCGTAACGGATGGATGACGTTTGCTTC
TGTTAGTGCAGTAACAGTTACACTATTACTTGTAGGTGTCTTTTTAACAGCGATTATGAATATGAACCATTTTGCGACGA
AAGTAGAGCAAGATGTTGAGATTCGTGTACACATTGATCCAGCAGCAAAAGAAGCTGATCAAAAGAAATTAGAAGATGAT
ATGAGTAAGATTGCAAAAGTAGAATCTATTAAATATTCTTCTAAAGAAGAAGAGTTAAAACGTTTAATTAAAAGCTTAGG
CGATAGCGGAAAGACGTTTGAGTTATTTGAACAAGATAACCCACTGAAAAACGTGTTCGTTGTAAAAGCGAAAGAACCAA
CAGATACAGCAACAATTGCGAAAAAGATTGAAAAAATGCAGTTTGTAAGTAATGTTCAGTACGGAAAAGGGCAAGTTGAA
CGATTATTTGATACTGTAAAAACTGGTCGTAACATTGGTATTGTGTTAATTGCTGGTCTTTTATTCACAGCGATGTTCTT
AATCTCTAACACAATTAAAATTACAATTTATGCTCGTAGTACAGAAATCGAAATTATGAAACTTGTAGGTGCAACAAACT
GGTTTATTCGTTGGCCGTTCTTGTTAGAGGGATTATTCCTAGGAGTATTAGGATCAATTATTCCAATTGGCTTAATTCTT
GTTACGTATAATTCACTACAAGGTATGTTTAACGAAAAACTTGGCGGAACAATTTTCGAACTTCTACCATATAGTCCGTT
CGTATTCCAATTAGCTGGTTTACTAGTATTAATTGGGGCTTTAATCGGTATGTGGGGAAGCGTAATGTCAATTCGTCGTT
TCTTAAAAGTATAA

Upstream 100 bases:

>100_bases
GCGACACATAACGCAGATATCGTAAATACAATCCGTCATCGTGTAATCGCGATTGAAGGCGGAAAAATTGTTCGAGATGA
GATTGAGGGAGGATACGGAT

Downstream 100 bases:

>100_bases
AAAGTTGCAAACATAATTCGTACAAGCTTATCATATAGTAGAAATAGGTAAAGGCATCACACGCTGTGTGATGCCTTTTG
CTACACCACCTGTGTGTTTT

Product: cell division ABC transporter permease FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKAKTLSRHLREGVKNLSRNGWMTFASVSAVTVTLLLVGVFLTAIMNMNHFATKVEQDVEIRVHIDPAAKEADQKKLEDD
MSKIAKVESIKYSSKEEELKRLIKSLGDSGKTFELFEQDNPLKNVFVVKAKEPTDTATIAKKIEKMQFVSNVQYGKGQVE
RLFDTVKTGRNIGIVLIAGLLFTAMFLISNTIKITIYARSTEIEIMKLVGATNWFIRWPFLLEGLFLGVLGSIIPIGLIL
VTYNSLQGMFNEKLGGTIFELLPYSPFVFQLAGLLVLIGALIGMWGSVMSIRRFLKV

Sequences:

>Translated_297_residues
MKAKTLSRHLREGVKNLSRNGWMTFASVSAVTVTLLLVGVFLTAIMNMNHFATKVEQDVEIRVHIDPAAKEADQKKLEDD
MSKIAKVESIKYSSKEEELKRLIKSLGDSGKTFELFEQDNPLKNVFVVKAKEPTDTATIAKKIEKMQFVSNVQYGKGQVE
RLFDTVKTGRNIGIVLIAGLLFTAMFLISNTIKITIYARSTEIEIMKLVGATNWFIRWPFLLEGLFLGVLGSIIPIGLIL
VTYNSLQGMFNEKLGGTIFELLPYSPFVFQLAGLLVLIGALIGMWGSVMSIRRFLKV
>Mature_297_residues
MKAKTLSRHLREGVKNLSRNGWMTFASVSAVTVTLLLVGVFLTAIMNMNHFATKVEQDVEIRVHIDPAAKEADQKKLEDD
MSKIAKVESIKYSSKEEELKRLIKSLGDSGKTFELFEQDNPLKNVFVVKAKEPTDTATIAKKIEKMQFVSNVQYGKGQVE
RLFDTVKTGRNIGIVLIAGLLFTAMFLISNTIKITIYARSTEIEIMKLVGATNWFIRWPFLLEGLFLGVLGSIIPIGLIL
VTYNSLQGMFNEKLGGTIFELLPYSPFVFQLAGLLVLIGALIGMWGSVMSIRRFLKV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=304, Percent_Identity=28.2894736842105, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 33214; Mature: 33214

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKTLSRHLREGVKNLSRNGWMTFASVSAVTVTLLLVGVFLTAIMNMNHFATKVEQDVE
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCE
IRVHIDPAAKEADQKKLEDDMSKIAKVESIKYSSKEEELKRLIKSLGDSGKTFELFEQDN
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
PLKNVFVVKAKEPTDTATIAKKIEKMQFVSNVQYGKGQVERLFDTVKTGRNIGIVLIAGL
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
LFTAMFLISNTIKITIYARSTEIEIMKLVGATNWFIRWPFLLEGLFLGVLGSIIPIGLIL
HHHHHHHHCCCEEEEEEEECCCHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHH
VTYNSLQGMFNEKLGGTIFELLPYSPFVFQLAGLLVLIGALIGMWGSVMSIRRFLKV
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAKTLSRHLREGVKNLSRNGWMTFASVSAVTVTLLLVGVFLTAIMNMNHFATKVEQDVE
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCE
IRVHIDPAAKEADQKKLEDDMSKIAKVESIKYSSKEEELKRLIKSLGDSGKTFELFEQDN
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
PLKNVFVVKAKEPTDTATIAKKIEKMQFVSNVQYGKGQVERLFDTVKTGRNIGIVLIAGL
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
LFTAMFLISNTIKITIYARSTEIEIMKLVGATNWFIRWPFLLEGLFLGVLGSIIPIGLIL
HHHHHHHHCCCEEEEEEEECCCHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHH
VTYNSLQGMFNEKLGGTIFELLPYSPFVFQLAGLLVLIGALIGMWGSVMSIRRFLKV
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]